Winter HS, Madara JL, Stafford RJ et al. Intraepithelial eosinophils: a new diagnostic criterion for reflux esophagitis. Gastroenterology. 1982;83:818–823.

Article  CAS  PubMed  Google Scholar 

Attwood SE, Smyrk TC, Demeester TR et al. Esophageal eosinophilia with dysphagia. A distinct clinicopathologic syndrome. Dig Dis Sci. 1993;38:109–116.

Article  CAS  PubMed  Google Scholar 

Straumann A, Spichtin HP, Bernoulli R et al. Idiopathic eosinophilic esophagitis: a frequently overlooked disease with typical clinical aspects and discrete endoscopic findings. Schweiz Med Wochenschr. 1994;124:1419–1429.

CAS  PubMed  Google Scholar 

Kelly KJ, Lazenby AJ, Rowe PC et al. Eosinophilic esophagitis attributed to gastroesophageal reflux: improvement with an amino acid-based formula. Gastroenterology. 1995;109:1503–1512.

Article  CAS  PubMed  Google Scholar 

Furuta GT, Liacouras CA, Collins MH et al. Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology. 2007;133:1342–1363.

Article  CAS  PubMed  Google Scholar 

Rothenberg ME, Hogan SP. The eosinophil. Annu Rev Immunol. 2006;24:147–174.

Article  CAS  PubMed  Google Scholar 

Collins MH. Histopathologic features of eosinophilic esophagitis and eosinophilic gastrointestinal diseases. Gastroenterol Clin North Am. 2014;43:257–268.

Article  PubMed  Google Scholar 

Liacouras CA, Furuta GT, Hirano I et al. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol. 2011;128:3–20.

Article  PubMed  Google Scholar 

Dellon ES, Gonsalves N, Hirano I et al. ACG Clinical Guideline: evidence based approach to the diagnosis and management of esophageal eosinophilia and eosinophilic esophagitis. Am J Gastroenterol. 2013;108:679–692.

Article  PubMed  Google Scholar 

Lucendo AJ, Molina-Infante J, Arias A et al. Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and management in children and adults. United European Gastroenterol J. 2017;5:335–358.

Article  PubMed  PubMed Central  Google Scholar 

Dellon ES, Liacouras CA, Molina-Infante J et al. Updated international consensus diagnostic criteria for eosinophilic esophagitis: proceedings of the AGREE conference. Gastroenterology. 2018;155:1022–1033.

Article  PubMed  Google Scholar 

Dellon ES, Speck O, Woodward K et al. Distribution and variability of esophageal eosinophilia in patients undergoing upper endoscopy. Mod Pathol. 2015;28:383–390.

Article  PubMed  Google Scholar 

Dellon ES, Gupta SK. A conceptual approach to understanding treatment response in eosinophilic esophagitis. Clin Gastroenterol Hepatol. 2019;17:2149–2160.

Article  PubMed  PubMed Central  Google Scholar 

Reed CC, Wolf WA, Cotton CC et al. Optimal histologic cutpoints for treatment response in patients with eosinophilic esophagitis: analysis of data from a prospective cohort study. Clin Gastroenterol Hepatol. 2018;16:226–233.

Article  PubMed  Google Scholar 

Dellon ES, Aderoju A, Woosley JT et al. Variability in diagnostic criteria for eosinophilic esophagitis: a systematic review. Am J Gastroenterol. 2007;102:2300–2313.

Article  PubMed  Google Scholar 

Collins MH, Martin LJ, Alexander ES et al. Newly developed and validated eosinophilic esophagitis histology scoring system and evidence that it outperforms peak eosinophil count for disease diagnosis and monitoring. Dis Esophagus. 2017;30:1–8.

CAS  PubMed  Google Scholar 

Dellon ES. The pathogenesis of eosinophilic esophagitis: beyond the eosinophil. Dig Dis Sci. 2013;58:1445–1448.

Article  PubMed  PubMed Central  Google Scholar 

O’Shea KM, Aceves SS, Dellon ES et al. Pathophysiology of eosinophilic esophagitis. Gastroenterology. 2018;154:333–345.

Article  CAS  PubMed  Google Scholar 

Kottyan LC, Parameswaran S, Weirauch MT et al. The genetic etiology of eosinophilic esophagitis. J Allergy Clin Immunol. 2020;145:9–15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wen T, Aronow BJ, Rochman Y et al. Single-cell RNA sequencing identifies inflammatory tissue T cells in eosinophilic esophagitis. J Clin Invest. 2019;129:2014–2028.

Article  PubMed  PubMed Central  Google Scholar 

Abonia JP, Blanchard C, Butz BB et al. Involvement of mast cells in eosinophilic esophagitis. J Allergy Clin Immunol. 2010;126:140–149.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Abonia JP, Franciosi JP, Rothenberg ME. TGF-beta1: mediator of a feedback loop in eosinophilic esophagitis–or should we really say mastocytic esophagitis? J Allergy Clin Immunol. 2010;126:1205–1207.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Aceves SS, Chen D, Newbury RO et al. Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-beta1, and increase esophageal smooth muscle contraction. J Allergy Clin Immunol. 2010;126:1198–1204.

Article  CAS  PubMed  Google Scholar 

Lucendo AJ, Navarro M, Comas C et al. Immunophenotypic characterization and quantification of the epithelial inflammatory infiltrate in eosinophilic esophagitis through stereology: an analysis of the cellular mechanisms of the disease and the immunologic capacity of the esophagus. Am J Surg Pathol. 2007;31:598–606.

Article  PubMed  Google Scholar 

Dellon ES, Speck O, Woodward K et al. Markers of eosinophilic inflammation for diagnosis of eosinophilic esophagitis and proton pump inhibitor-responsive esophageal eosinophilia: a prospective study. Clin Gastroenterol Hepatol. 2014;12:2015–2022.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tappata M, Eluri S, Perjar I et al. Association of mast cells with clinical, endoscopic, and histologic findings in adults with eosinophilic esophagitis. Allergy. 2018;73:2088–2092.

Article  PubMed  Google Scholar 

Doyle AD, Masuda MY, Pyon GC et al. Detergent exposure induces epithelial barrier dysfunction and eosinophilic inflammation in the esophagus. Allergy. 2023;78:192–201.

Article  CAS  PubMed  Google Scholar 

Doyle LA, Odze RD. Eosinophilic esophagitis without abundant eosinophils? The expanding spectrum of a disease that is difficult to define. Dig Dis Sci. 2011;56:1923–1925.

Article  PubMed  Google Scholar 

Pasricha S, Gupta A, Reed CC et al. Lymphocytic esophagitis: an emerging clinicopathologic disease associated with dysphagia. Dig Dis Sci. 2016;61:2935–2941.

Article  PubMed  PubMed Central  Google Scholar 

Straumann A, Blanchard C, Radonjic-Hoesli S et al. A new eosinophilic esophagitis (EoE)-like disease without tissue eosinophilia found in EoE families. Allergy. 2016;71:889–900.

Article  CAS  PubMed  Google Scholar 

Greuter T, Straumann A, Fernandez-Marrero Y et al. Characterization of eosinophilic esophagitis variants by clinical, histological, and molecular analyses: a cross-sectional multi-center study. Allergy. 2022;77:2520–2533.

Article  CAS  PubMed  Google Scholar 

Ishimura N, Sumi S, Okada M et al. Is asymptomatic esophageal eosinophilia the same disease entity as eosinophilic esophagitis? Clin Gastroenterol Hepatol. 2019;17:1405–1407.

Article  PubMed  Google Scholar 

Ocampo AA, Genta RM, Dellon ES. Mast cell esophagitis: a novel entity in patients with unexplained esophageal symptoms. Dysphagia. 2023 Aug 21. Online ahead of print.

Safroneeva E, Straumann A, Coslovsky M et al. Symptoms have modest accuracy in detecting endoscopic and histologic remission in adults with eosinophilic esophagitis. Gastroenterology. 2016;150:581–590.

Article  PubMed  Google Scholar 

von Arnim U, Biedermann L, Aceves SS et al. Monitoring patients with eosinophilic esophagitis in routine clinical practice - international expert recommendations. Clin Gastroenterol Hepatol. 2023;21:2526–2533.

Article  PubMed  Google Scholar 

Runge TM, Eluri S, Woosley JT et al. Control of inflammation decreases the need for subsequent esophageal dilation in patients with eosinophilic esophagitis. Dis Esoph. 2017;30:1–7.

Article  CAS  Google Scholar 

Hirano I, Furuta GT. Approaches and challenges to management of pediatric and adult patients with eosinophilic esophagitis. Gastroenterology. 2020;158:840–851.

Article  CAS  PubMed  Google Scholar 

Liu Z, Hu Y, Yu X et al. Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus. Am J Physiol Gastrointest Liver Physiol. 2015;308:G482–G488.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Schoepfer AM, Simko A, Bussmann C et al. Eosinophilic esophagitis: relationship of subepithelial eosinophilic inflammation with epithelial histology, endoscopy, blood eosino