S.L. Cohn, A.D. Pearson, W.B. London, T. Monclair, P.F. Ambros, G.M. Brodeur, A. Faldum, B. Hero, T. Iehara, D. Machin, V. Mosseri, T. Simon, A. Garaventa, V. Castel, K.K. Matthay, I.T. Force, The international neuroblastoma risk group (INRG) classification system: An INRG task Force report. J Clin Oncol 27, 289–297 (2009)

Article  PubMed  PubMed Central  Google Scholar 

J.M. Maris, Recent advances in neuroblastoma. N Engl J Med 362, 2202–2211 (2010)

Article  CAS  PubMed  PubMed Central  Google Scholar 

C.P. Reynolds, K.K. Matthay, J.G. Villablanca, B.J. Maurer, Retinoid therapy of high-risk neuroblastoma. Cancer Lett 197, 185–192 (2003)

Article  CAS  PubMed  Google Scholar 

K.K. Matthay, C.P. Reynolds, R.C. Seeger, H. Shimada, E.S. Adkins, D. Haas-Kogan, R.B. Gerbing, W.B. London, J.G. Villablanca, Long-term results for children with high-risk neuroblastoma treated on a randomized trial of myeloablative therapy followed by 13-cis-retinoic acid: A children's oncology group study. J Clin Oncol 27, 1007–1013 (2009)

Article  CAS  PubMed  PubMed Central  Google Scholar 

S. Hatakeyama, TRIM proteins and cancer. Nat Rev Cancer 11, 792–804 (2011)

Article  CAS  PubMed  Google Scholar 

B. Le Douarin, C. Zechel, J.M. Garnier, Y. Lutz, L. Tora, P. Pierrat, D. Heery, H. Gronemeyer, P. Chambon, R. Losson, The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J 14, 2020–2033 (1995)

Article  PubMed  PubMed Central  Google Scholar 

B. Le Douarin, A.L. Nielsen, J.M. Garnier, H. Ichinose, F. Jeanmougin, R. Losson, P. Chambon, A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J 15, 6701–6715 (1996)

Article  PubMed  PubMed Central  Google Scholar 

W.W. Tsai, Z. Wang, T.T. Yiu, K.C. Akdemir, W. Xia, S. Winter, C.Y. Tsai, X. Shi, D. Schwarzer, W. Plunkett, B. Aronow, O. Gozani, W. Fischle, M.C. Hung, D.J. Patel, M.C. Barton, TRIM24 links a non-canonical histone signature to breast cancer. Nature. 468, 927–932 (2010)

Article  CAS  PubMed  PubMed Central  Google Scholar 

L.H. Zhang, A.A. Yin, J.X. Cheng, H.Y. Huang, X.M. Li, Y.Q. Zhang, N. Han, X. Zhang, TRIM24 promotes glioma progression and enhances chemoresistance through activation of the PI3K/Akt signaling pathway. Oncogene. 34, 600–610 (2015)

Article  CAS  PubMed  Google Scholar 

D. Lv, Y. Li, W. Zhang, A.A. Alvarez, L. Song, J. Tang, W.Q. Gao, B. Hu, S.Y. Cheng, H. Feng, TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma. Nat Commun 8, 1454 (2017)

Article  PubMed  PubMed Central  Google Scholar 

G. Zhao, C. Liu, X. Wen, G. Luan, L. Xie, X. Guo, The translational values of TRIM family in pan-cancers: From functions and mechanisms to clinics. Pharmacol Ther 227, 107881 (2021)

Article  CAS  PubMed  Google Scholar 

K. Allton, A.K. Jain, H.M. Herz, W.W. Tsai, S.Y. Jung, J. Qin, A. Bergmann, R.L. Johnson, M.C. Barton, Trim24 targets endogenous p53 for degradation. Proc Natl Acad Sci U S A 106, 11612–11616 (2009)

Article  CAS  PubMed  PubMed Central  Google Scholar 

A.C. Groner, L. Cato, J. de Tribolet-Hardy, T. Bernasocchi, H. Janouskova, D. Melchers, R. Houtman, A.C.B. Cato, P. Tschopp, L. Gu, A. Corsinotti, Q. Zhong, C. Fankhauser, C. Fritz, C. Poyet, U. Wagner, T. Guo, R. Aebersold, L.A. Garraway, et al., TRIM24 is an oncogenic transcriptional activator in prostate Cancer. Cancer Cell 29, 846–858 (2016)

Article  CAS  PubMed  PubMed Central  Google Scholar 

K. Khetchoumian, M. Teletin, J. Tisserand, M. Mark, B. Herquel, M. Ignat, J. Zucman-Rossi, F. Cammas, T. Lerouge, C. Thibault, D. Metzger, P. Chambon, R. Losson, Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha. Nat Genet 39, 1500–1506 (2007)

Article  CAS  PubMed  Google Scholar 

J. Tisserand, K. Khetchoumian, C. Thibault, D. Dembele, P. Chambon, R. Losson, Tripartite motif 24 (Trim24/Tif1alpha) tumor suppressor protein is a novel negative regulator of interferon (IFN)/signal transducers and activators of transcription (STAT) signaling pathway acting through retinoic acid receptor alpha (Raralpha) inhibition. J Biol Chem 286, 33369–33379 (2011)

Article  CAS  PubMed  PubMed Central  Google Scholar 

H. Feng, B. Hu, K.W. Liu, Y. Li, X. Lu, T. Cheng, J.J. Yiin, S. Lu, S. Keezer, T. Fenton, F.B. Furnari, R.L. Hamilton, K. Vuori, J.N. Sarkaria, M. Nagane, R. Nishikawa, W.K. Cavenee, S.Y. Cheng, Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRalpha-stimulated glioma tumorigenesis in mice and humans. J Clin Invest 121, 4670–4684 (2011)

Article  CAS  PubMed  PubMed Central  Google Scholar 

Y. Hu, G.K. Smyth, ELDA: Extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays. J Immunol Methods 347, 70–78 (2009)

Article  CAS  PubMed  Google Scholar 

K.W. Liu, H. Feng, R. Bachoo, A. Kazlauskas, E.M. Smith, K. Symes, R.L. Hamilton, M. Nagane, R. Nishikawa, B. Hu, S.Y. Cheng, SHP-2/PTPN11 mediates gliomagenesis driven by PDGFRA and INK4A/ARF aberrations in mice and humans. J Clin Invest 121, 905–917 (2011)

Article  CAS  PubMed  PubMed Central  Google Scholar 

G. Yu, L.-G. Wang, Y. Han, Q.-Y. He, clusterProfiler: An R package for comparing biological themes among gene clusters. OMICS. 16, 284–287 (2012)

Article  CAS  PubMed  PubMed Central  Google Scholar 

N.J. Balamuth, A. Wood, Q. Wang, J. Jagannathan, P. Mayes, Z. Zhang, Z. Chen, E. Rappaport, J. Courtright, B. Pawel, B. Weber, R. Wooster, E.O. Sekyere, G.M. Marshall, J.M. Maris, Serial transcriptome analysis and cross-species integration identifies centromere-associated protein E as a novel neuroblastoma target. Cancer Res 70, 2749–2758 (2010)

Article  CAS  PubMed  PubMed Central  Google Scholar 

I. Janoueix-Lerosey, D. Lequin, L. Brugières, A. Ribeiro, L. de Pontual, V. Combaret, V. Raynal, A. Puisieux, G. Schleiermacher, G. Pierron, D. Valteau-Couanet, T. Frebourg, J. Michon, S. Lyonnet, J. Amiel, O. Delattre, Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature. 455, 967–970 (2008)

Article  CAS  PubMed  Google Scholar 

P. Rajbhandari, G. Lopez, C. Capdevila, B. Salvatori, J. Yu, R. Rodriguez-Barrueco, D. Martinez, M. Yarmarkovich, N. Weichert-Leahey, B.J. Abraham, M.J. Alvarez, A. Iyer, J.L. Harenza, D. Oldridge, K. De Preter, J. Koster, S. Asgharzadeh, R.C. Seeger, J.S. Wei, et al., Cross-cohort analysis identifies a TEAD4-MYCN positive feedback loop as the Core regulatory element of high-risk neuroblastoma. Cancer Discov 8, 582–599 (2018)

Article  CAS  PubMed  PubMed Central  Google Scholar 

S.M.-I. Consortium, A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the sequencing quality control consortium. Nat Biotechnol 32, 903–914 (2014)

Article  Google Scholar 

X. Han, B. Gui, C. Xiong, L. Zhao, J. Liang, L. Sun, X. Yang, W. Yu, W. Si, R. Yan, X. Yi, D. Zhang, W. Li, L. Li, J. Yang, Y. Wang, Y.E. Sun, D. Zhang, A. Meng, Y. Shang, Destabilizing LSD1 by Jade-2 promotes neurogenesis: An antibraking system in neural development. Mol Cell 55, 482–494 (2014)

Article  CAS  PubMed  Google Scholar 

S. Amente, G. Milazzo, M.C. Sorrentino, S. Ambrosio, G. Di Palo, L. Lania, G. Perini, B. Majello, Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma. Oncotarget. 6, 14572–14583 (2015)

Article  PubMed  PubMed Central  Google Scholar 

M.G. Lee, C. Wynder, N. Cooch, R. Shiekhattar, An essential role for CoREST in nucleosomal histone 3 lysine 4 demethylation. Nature. 437, 432–435 (2005)

Article  CAS  PubMed  Google Scholar 

J. Wysocka, T.A. Milne, C.D. Allis, Taking LSD 1 to a new high. Cell. 122, 654–658 (2005)

Article  CAS  PubMed  Google Scholar 

B. Lakowski, I. Roelens, S. Jacob, CoREST-like complexes regulate chromatin modification and neuronal gene expression. J Mol Neurosci 29, 227–239 (2006)

Article  CAS  PubMed  Google Scholar 

Y. Song, L. Dagil, L. Fairall, N. Robertson, M. Wu, T.J. Ragan, C.G. Savva, A. Saleh, N. Morone, M.B.A. Kunze, A.G. Jamieson, P.A. Cole, D.F. Hansen, J.W.R. Schwabe, Mechanism of crosstalk between the LSD1 demethylase and HDAC1 deacetylase in the CoREST complex. Cell Rep 30, 2699–2711 (2020)

Article  CAS  PubMed  PubMed Central  Google Scholar 

J.H. Schulte, S. Lim, A. Schramm, N. Friedrichs, J. Koster, R. Versteeg, I. Ora, K. Pajtler, L. Klein-Hitpass, S. Kuhfittig-Kulle, E. Metzger, R. Schule, A. Eggert, R. Buettner, J. Kirfel, Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: Implications for therapy. Cancer Res 69, 2065–2071 (2009)

Article  CAS  PubMed  Google Scholar 

N. Bayeva, E. Coll, O. Piskareva, Differentiating neuroblastoma: A systematic review of the retinoic acid, its derivatives, and synergistic interactions. J Pers Med 11, 211 (2021)

Article  PubMed  PubMed Central  Google Scholar 

K. Chen, Y. Cai, C. Cheng, J. Zhang, F. Lv, G. Xu, P. Duan, Y. Wu, Z. Wu, MYT1 attenuates neuroblastoma cell differentiation by interacting with the LSD1/CoREST complex. Oncogene. 39, 4212–4226 (2020)

Article