Thatch KA, Schwartz MZ, Yoo EY, Mendelson KG, Duke DS (2008) Modulation of the inflammatory response and apoptosis using epidermal growth factor and hepatocyte growth factor in a liver injury model: a potential approach to the management and treatment of cholestatic liver disease. J Pediatr Surg 43(12):2169–2173

Article  PubMed  Google Scholar 

Sugimoto T, Yamashita S, Ishigami M, Sakai N, Hirano K, Tahara M, Matsumoto K, Nakamura T, Matsuzawa Y (2002) Decreased microsomal triglyceride transfer protein activity contributes to initiation of alcoholic liver steatosis in rats. J Hepatol 36(2):157–162

Article  CAS  PubMed  Google Scholar 

Kosone T, Takagi H, Horiguchi N, Ariyama Y, Otsuka T, Sohara N, Kakizaki S, Sato K, Mori M (2007) HGF ameliorates a high-fat diet-induced fatty liver. Am J Physiol Gastrointest Liver Physiol 293(1):G204-210

Article  CAS  PubMed  Google Scholar 

Matsukubo M, Yano K, Kaji T, Sugita K, Onishi S, Harumatsu T, Nagano A, Matsui M, Murakami M, Yamada K, Yamada W, Muto M, Kumagai K, Ido A, Ieiri S (2021) The administration of hepatocyte growth factor prevents total parenteral nutrition-induced hepatocellular injury in a rat model. Pediatr Surg Int 37(3):353–361

Article  PubMed  Google Scholar 

Yano K, Kaji T, Onishi S, Machigashira S, Nagai T, Harumatsu T, Yamada K, Yamada W, Muto M, Nakame K, Mukai M, Ieiri S (2019) Novel effect of glucagon-like peptide-2 for hepatocellular injury in a parenterally fed rat model of short bowel syndrome. Pediatr Surg Int 35(12):1345–1351

Article  PubMed  Google Scholar 

Yano K, Sugita K, Muto M, Matsukubo M, Onishi S, Kedoin C, Matsui M, Murakami M, Harumatsu T, Yamada K, Yamada W, Kumagai K, Ido A, Kaji T, Ieiri S (2022) The preventive effect of recombinant human hepatocyte growth factor for hepatic steatosis in a rat model of short bowel syndrome. J Pediatr Surg 57(7):1286–1292

Article  PubMed  Google Scholar 

Sugita K, Kaji T, Yano K, Matsukubo M, Nagano A, Matsui M, Murakami M, Harumatsu T, Onishi S, Yamada K, Yamada W, Muto M, Kumagai K, Ido A, Ieiri S (2021) The protective effects of hepatocyte growth factor on the intestinal mucosal atrophy induced by total parenteral nutrition in a rat model. Pediatr Surg Int 37(12):1743–1753

Article  PubMed  PubMed Central  Google Scholar 

Nabeshima A, Yamada S, Guo X, Tanimoto A, Wang KY, Shimajiri S, Kimura S, Tasaki T, Noguchi H, Kitada S, Watanabe T, Fujii J, Kohno K, Sasaguri Y (2013) Peroxiredoxin 4 protects against nonalcoholic steatohepatitis and type 2 diabetes in a nongenetic mouse model. Antioxid Redox Signal 19(17):1983–1998

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nishikoba N, Kumagai K, Kanmura S, Nakamura Y, Ono M, Eguchi H, Kamibayashiyama T, Oda K, Mawatari S, Tanoue S, Hashimoto S, Tsubouchi H, Ido A (2020) HGF-MET signaling shifts m1 macrophages toward an M2-like phenotype through PI3K-mediated induction of arginase-1 expression. Front Immunol 11:2135

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kanda Y (2013) Investigation of the freely available easy-to-use software “EZR” for medical statistics. Bone Marrow Transplant 48(3):452–458

Article  CAS  PubMed  Google Scholar 

Katz MS, Thatch KA, Schwartz MZ (2010) Dose variation of hepatocyte growth factor and its effects on an animal model of TPN-induced liver injury. J Surg Res 163(2):294–298

Article  CAS  PubMed  Google Scholar 

Gao M, Fan S, Goldberg ID, Laterra J, Kitsis RN, Rosen EM (2001) Hepatocyte growth factor/scatter factor blocks the mitochondrial pathway of apoptosis signaling in breast cancer cells. J Biol Chem 276(50):47257–47265

Article  CAS  PubMed  Google Scholar 

Puche JE, Saiman Y, Friedman SL (2013) Hepatic stellate cells and liver fibrosis. Compr Physiol 3(4):1473–1492

Article  PubMed  Google Scholar 

Narmada BC, Chia SM, Tucker-Kellogg L, Yu H (2013) HGF regulates the activation of TGF-beta1 in rat hepatocytes and hepatic stellate cells. J Cell Physiol 228(2):393–401

Article  CAS  PubMed  Google Scholar 

Tanaka S, Hikita H, Tatsumi T, Sakamori R, Nozaki Y, Sakane S, Shiode Y, Nakabori T, Saito Y, Hiramatsu N, Tabata K, Kawabata T, Hamasaki M, Eguchi H, Nagano H, Yoshimori T, Takehara T (2016) Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice. Hepatology 64(6):1994–2014

Article  CAS  PubMed  Google Scholar 

Moumen A, Patane S, Porras A, Dono R, Maina F (2007) Met acts on Mdm2 via mTOR to signal cell survival during development. Development 134(7):1443–1451

Article  CAS  PubMed  Google Scholar 

Gallo S, Gatti S, Sala V, Albano R, Costelli P, Casanova E, Comoglio PM, Crepaldi T (2014) Agonist antibodies activating the Met receptor protect cardiomyoblasts from cobalt chloride-induced apoptosis and autophagy. Cell Death Dis 5(4):e1185

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bagias G, Misiakos EP, Charalampopoulos A, Zavras N, Sakellariou S, Schizas D, Sukhotnik I, Giamarelos E, Pikoulis E (2023) The effect of hepatocyte growth factor on intestinal adaption in an experimental model of short bowel syndrome. Pediatr Surg Int 39(1):80

Article  PubMed  Google Scholar 

Schwartz MZ, Kato Y, Yu D, Lukish JR (2000) Growth-factor enhancement of compromised gut function following massive small-bowel resection. Pediatr Surg Int 16(3):174–175

Article  CAS  PubMed  Google Scholar 

Kato Y, Yu D, Schwartz MZ (1998) Enhancement of intestinal adaptation by hepatocyte growth factor. J Pediatr Surg 33(2):235–239

Article  CAS  PubMed  Google Scholar 

Kato Y, Yu D, Schwartz MZ (1998) Hepatocyte growth factor up-regulates SGLT1 and GLUT5 gene expression after massive small bowel resection. J Pediatr Surg 33(1):13–15

Article  CAS  PubMed  Google Scholar 

Kato Y, Yu D, Lukish JR, Schwartz MZ (1997) Hepatocyte growth factor enhances intestinal mucosal cell function and mass in vivo. J Pediatr Surg 32(7):991–994

Article  CAS  PubMed  Google Scholar 

Fafalios A, Ma J, Tan X, Stoops J, Luo J, Defrances MC, Zarnegar R (2011) A hepatocyte growth factor receptor (Met)-insulin receptor hybrid governs hepatic glucose metabolism. Nat Med 17(12):1577–1584

Article  CAS  PubMed  PubMed Central  Google Scholar