Down regulation of the inverse relationship between parathyroid hormone and irisin in male vitamin D-sufficient HIV patients

Li F, Li Y, Duan Y, Hu CA, Tang Y, Yin Y (2017) Myokines and adipokines: Involvement in the crosstalk between skeletal muscle and adipose tissue. Cytokine Growth Factor Rev 33:73–82. https://doi.org/10.1016/j.cytogfr.2016.10.003

Article  CAS  PubMed  Google Scholar 

Chen W, Wang L, You W, Shan T (2021) Myokines mediate the cross talk between skeletal muscle and other organs. J Cell Physiol 236:2393–2412. https://doi.org/10.1002/jcp.30033

Article  CAS  PubMed  Google Scholar 

Leal LG, Lopes MA, Batista ML Jr (2018) Physical exercise-induced myokines and muscle-adipose tissue crosstalk: a review of current knowledge and the implications for health and metabolic diseases. Front Physiol 9:1307. https://doi.org/10.3389/fphys.2018.01307

Article  PubMed  PubMed Central  Google Scholar 

Karras SN, Koufakis T, Adamidou L, Dimakopoulos G, Karalazou P, Thisiadou K, Makedou K, Zebekakis P, Kotsa K (2022) Implementation of Christian Orthodox fasting improves plasma adiponectin concentrations compared with time-restricted eating in overweight premenopausal women. Int J Food Sci Nutr 73:210–220. https://doi.org/10.1080/09637486.2021.1941803

Article  PubMed  Google Scholar 

Krause MP, Milne KJ, Hawke TJ (2019) Adiponectin-consideration for its role in skeletal muscle health. Int J Mol Sci 20:1528. https://doi.org/10.3390/ijms20071528

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nawrocki AR, Scherer PE (2004) The delicate balance between fat and muscle: adipokines in metabolic disease and musculoskeletal inflammation. Curr Opin Pharmacol 4:281–289. https://doi.org/10.1016/j.coph.2004.03.003

Article  CAS  PubMed  Google Scholar 

Waseem R, Shamsi A, Mohammad T, Hassan MI, Kazim SN, Chaudhary AA, Rudayni HA, Al-Zharani M, Ahmad F, Islam A (2022) FNDC5/irisin: physiology and pathophysiology. Molecules 27:1118. https://doi.org/10.3390/molecules27031118

Article  CAS  PubMed  PubMed Central  Google Scholar 

Maak S, Norheim F, Drevon CA, Erickson HP (2021) Progress and challenges in the biology of FNDC5 and Irisin. Endocr Rev 42:436–456. https://doi.org/10.1210/endrev/bnab003

Article  PubMed  PubMed Central  Google Scholar 

Cho E, Jeong DY, Kim JG, Lee S (2021) The acute effects of swimming exercise on PGC-1α-FNDC5/irisin-UCP1 expression in male C57BL/6J mice. Metabolites 11:111. https://doi.org/10.3390/metabo11020111

Article  CAS  PubMed  PubMed Central  Google Scholar 

Estell EG, Le PT, Vegting Y, Kim H, Wrann C, Bouxsein ML, Nagano K, Baron R, Spiegelman BM, Rosen CJ (2020) Irisin directly stimulates osteoclastogenesis and bone resorption in vitro and in vivo. Elife 9:e58172. https://doi.org/10.7554/eLife.58172

Article  CAS  PubMed  PubMed Central  Google Scholar 

Kawao N, Kawaguchi M, Ohira T, Ehara H, Mizukami Y, Takafuji Y, Kaji H (2022) Renal failure suppresses muscle irisin expression, and irisin blunts cortical bone loss in mice. J Cachexia Sarcopenia Muscle 13:758–771. https://doi.org/10.1002/jcsm.12892

Article  PubMed  PubMed Central  Google Scholar 

Luo Y, Ma Y, Qiao X, Zeng R, Cheng R, Nie Y, Li S, Shen X, Yang M, Xu CC, Xu L (2020) Irisin ameliorates bone loss in ovariectomized mice. Climacteric 23:496–504. https://doi.org/10.1080/13697137.2020.1745768

Article  CAS  PubMed  Google Scholar 

Colaianni G, Cuscito C, Mongelli T, Pignataro P, Buccoliero C, Liu P, Lu P, Sartini L, Di Comite M, Mori G, Di Benedetto A, Brunetti G, Yuen T, Sun L, Reseland JE, Colucci S, New MI, Zaidi M, Cinti S, Grano M (2015) The myokine irisin increases cortical bone mass. Proc Natl Acad Sci U S A 112:12157–12162. https://doi.org/10.1073/pnas.1516622112

Article  CAS  PubMed  PubMed Central  Google Scholar 

Freitas P, Carvalho D, Santos AC, Madureira AJ, Martinez E, Pereira J, Sarmento A, Medina JL (2014) Adipokines, hormones related to body composition, and insulin resistance in HIV fat redistribution syndrome. BMC Infect Dis 14:347. https://doi.org/10.1186/1471-2334-14-347

Article  CAS  PubMed  PubMed Central  Google Scholar 

Tsiodras S, Mantzoros C (2006) Leptin and adiponectin in the HIV associated metabolic syndrome: physiologic and therapeutic implications. Am J Infect Dis 2:141–152. https://doi.org/10.3844/ajidsp.2006.141.152

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nix LM, Tien PC (2014) Metabolic syndrome, diabetes, and cardiovascular risk in HIV. Curr HIV/AIDS Rep 11:271–278. https://doi.org/10.1007/s11904-014-0219-7

Article  PubMed  PubMed Central  Google Scholar 

Biver E (2022) Osteoporosis and HIV Infection. Calcif Tissue Int 110:624–640. https://doi.org/10.1007/s00223-022-00946-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Premaor MO, Compston JE (2020) People living with HIV and fracture risk. Osteoporos Int 31:1633–1644. https://doi.org/10.1007/s00198-020-05350-y

Article  CAS  PubMed  Google Scholar 

Food Processor Analysis Software. 2018. https://www.esha.com/products/food-processor/. Accessed July 2 2022.

Papathanasiou G, Georgoudis G, Papandreou M, Spyropoulos P, Georgakopoulos D, Kalfakakou V, Evangelou A (2009) Reliability measures of the short International Physical Activity Questionnaire (IPAQ) in Greek young adults. Hellenic J Cardiol 50:283–294

PubMed  Google Scholar 

Mitsionis G, Pakos EE, Stafilas KS, Paschos N, Papakostas T, Beris AE (2009) Normative data on hand grip strength in a Greek adult population. Int Orthop 33:713–717. https://doi.org/10.1007/s00264-008-0551-x

Article  PubMed  Google Scholar 

Scherzer R, Shen W, Heymsfield SB, Lewis CE, Kotler DP, Punyanitya M, Bacchetti P, Shlipak MG, Grunfeld C (2011) Study of fat redistribution and metabolic change in HIV infection (FRAM). Intermuscular adipose tissue and metabolic associations in HIV infection. Obesity (Silver Spring) 19:283–291. https://doi.org/10.1038/oby.2010.115

Article  CAS  PubMed  Google Scholar 

Karras SN, Koufakis T, Tsekmekidou X, Antonopoulou V, Zebekakis P, Kotsa K (2020) Increased parathyroid hormone is associated with higher fasting glucose in individuals with normocalcemic primary hyperparathyroidism and prediabetes: a pilot study. Diabetes Res Clin Pract 160:107985. https://doi.org/10.1016/j.diabres.2019.107985

Article  CAS  PubMed  Google Scholar 

Sajid S, Zariwala MG, Mackenzie R, Turner M, Nell T, Bellary S, Renshaw D (2022) Suppression of anti-inflammatory mediators in metabolic disease may be driven by overwhelming pro-inflammatory drivers. Nutrients 14:2360. https://doi.org/10.3390/nu14112360

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu MV, Bikopoulos G, Hung S, Ceddia RB (2014) Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: impact on whole-body energy expenditure. J Biol Chem 289:34129–34140. https://doi.org/10.1074/jbc.M114.591008

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rendina-Ruedy E, Rosen CJ (2022) Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks. Mol Metab. 60:101480. https://doi.org/10.1016/j.molmet.2022.101480

Article  CAS  PubMed  PubMed Central  Google Scholar 

Addy CL, Gavrila A, Tsiodras S, Brodovicz K, Karchmer AW, Mantzoros CS (2003) Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy. J Clin Endocrinol Metab 88:627–636. https://doi.org/10.1210/jc.2002-020795

Article  CAS  PubMed  Google Scholar 

Mynarcik DC, McNurlan MA, Steigbigel RT, Fuhrer J, Gelato MC (2000) Association of severe insulin resistance with both loss of limb fat and elevated serum tumor necrosis factor receptor levels in HIV lipodystrophy. J Acquir Immune Defic Syndr 25:312–321. https://doi.org/10.1097/00042560-200012010-00004

Article  CAS  PubMed  Google Scholar 

Ledru E, Christeff N, Patey O, de Truchis P, Melchior JC, Gougeon ML (2000) Alteration of tumor necrosis factor-alpha T-cell homeostasis following potent antiretroviral therapy: contribution to the development of human immunodeficiency virus-associated lipodystrophy syndrome. Blood 95:3191–3198

Article  CAS  PubMed  Google Scholar 

Jan V, Cervera P, Maachi M, Baudrimont M, Kim M, Vidal H, Girard PM, Levan P, Rozenbaum W, Lombès A, Capeau J, Bastard JP (2004) Altered fat differentiation and adipocytokine expression are inter-related and linked to morphological changes and insulin resistance in HIV-1-infected lipodystrophic patients. Antivir Ther 9:555–564

Article  CAS  PubMed  Google Scholar 

Kinlaw WB, Marsh B (2004) Adiponectin and HIV-lipodystrophy: taking HAART. Endocrinology 145:484–486. https://doi.org/10.1210/en.2003-1513

Article  CAS  PubMed  Google Scholar 

Tong Q, Sankalé JL, Hadigan CM, Tan G, Rosenberg ES, Kanki PJ, Grinspoon SK, Hotamisligil GS (2003) Regulation of adiponectin in human immunodeficiency virus-infected patients: relationship to body composition and metabolic indices. J Clin Endocrinol Metab 88:1559–1564. https://doi.org/10.1210/jc.2002-021600

Article  CAS 

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