Prevalence of beta thalassemia carriers in India: a systematic review and meta-analysis

Achoubi N, Asghar M, Saraswathy KN, Murry B (2012) Prevalence of β-thalassemia and hemoglobin E in two migrant populations of Manipur, North East India. Genet Test Mol Biomarkers 16:1195–1200. https://doi.org/10.1089/gtmb.2011.0373

Article  CAS  PubMed  Google Scholar 

Allagh KP, Shamanna BR, Murthy GVS, Ness AR, Doyle P, Neogi SB, Pant HB (2015) Birth prevalence of neural tube defects and orofacial clefts in India: a systematic review and meta-analysis. PLoS ONE 10:e0118961. https://doi.org/10.1371/journal.pone.0118961

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ambekar SS, Phadke MA, Balpande DN, Mokashi GD, Khedkar VA (2001) The prevalence and heterogeneity of beta thalassemia mutations in the Western Maharashtra Population : a hospital based study. Indian J Hum Genet 1:219–223

Article  Google Scholar 

Balgir RS (2005a) The spectrum of haemoglobin variants in two scheduled tribes of Sundargarh district in north-western Orissa, India. Ann Hum Biol 32:560–573. https://doi.org/10.1080/03014460500228741

Article  CAS  PubMed  Google Scholar 

Balgir RS (2005b) Spectrum of hemoglobinopathies in the state of Orissa, India: a ten years cohort study. J Assoc Physicians India 53:1021–1026

CAS  PubMed  Google Scholar 

Balgir RS (2010) Genetic diversity of hemoglobinopathies, G6PD deficiency, and ABO and Rhesus blood groups in two isolates of a primitive Kharia Tribe in Sundargarh District of Northwestern Orissa, India. J Community Genet 1:117–123. https://doi.org/10.1007/s12687-010-0016-y

Article  CAS  PubMed  PubMed Central  Google Scholar 

Balgir RS, Murmu B, Dash BP (1999) Hereditary hemolytic disorders among the Ashram school children in Mayurbhanj district of Orissa. J Assoc Physicians India 47:987–990

CAS  PubMed  Google Scholar 

Baruah MK, Saikia M, Baruah A (2014) Pattern of hemoglobinopathies and thalassemias in upper Assam region of North Eastern India : high performance liquid chromatography studies in 9000 patients. Indian J Pathol Microbiol 57:236–243. https://doi.org/10.4103/0377-4929.134680

Article  PubMed  Google Scholar 

Baxi A, Manila K, Kadhi P, Heena B (2013) Carrier screening for β thalassemia in pregnant Indian women: experience at a single center in Madhya Pradesh. Indian J Hematol Blood Transfus 29:71–74. https://doi.org/10.1007/s12288-012-0165-8

Article  PubMed  Google Scholar 

Bhargava M, Kumar V, Pandey H, Singh V, Misra V, Gupta P (2020) Role of hematological indices as a screening tool of beta thalassemia trait in Eastern Uttar Pradesh: an institutional study. Indian J Hematol Blood Transfus 36:719–724. https://doi.org/10.1007/s12288-020-01282-z

Article  PubMed  PubMed Central  Google Scholar 

Bhide P, Kar A (2018) A national estimate of the birth prevalence of congenital anomalies in India: systematic review and meta-analysis. BMC Pediatr 18:1–10. https://doi.org/10.1186/s12887-018-1149-0

Article  Google Scholar 

Bhukhanvala DS, Sorathiya SM, Shah AP, Patel AG, Gupte SC (2012) Prevalence and hematological profile of β-thalassemia and sickle cell anemia in four communities of Surat city. Indian J Hum Genet 18:167–171. https://doi.org/10.4103/0971-6866.100752

Article  CAS  PubMed  PubMed Central  Google Scholar 

Bhukhanvala DS, Sorathiya SM, Sawant P, Colah R, Ghosh K, Gupte SC (2013) Antenatal screening for identification of couples for prenatal diagnosis of severe hemoglobinopathies in Surat, South gujarat. J Obstet Gynaecol India 63:123–127. https://doi.org/10.1007/s13224-012-0271-4

Article  PubMed  Google Scholar 

Chandrashekar V, Soni M (2011) Hemoglobin disorders in South India. ISRN Hematol 748939:1–6. https://doi.org/10.5402/2011/748939

Article  Google Scholar 

Chatterjee T, Chakravarty A, Chakravarty S (2015) Population screening and prevention strategies for thalassemias and other hemoglobinopathies of Eastern India : experience of 18,166 cases. Hemoglobin 39:384–388. https://doi.org/10.3109/03630269.2015.1068799

Article  CAS  PubMed  Google Scholar 

Chhotray GP, Dash BP, Ranjit M (2004) Spectrum of hemoglobinopathies in Orissa, India. Hemoglobin 28:117–122. https://doi.org/10.1081/HEM-120034244

Article  CAS  PubMed  Google Scholar 

Choubisa SL (1985) Erythrocyte glucose-6-phosphate dehydrogenase deficiency & thalassemic genes in scheduled castes of Rajasthan. Indian J Med Res 82:554–558

CAS  PubMed  Google Scholar 

Choubisa SL (1991) Abnormal haemoglobins, thalassaemia and G-6-PD enzyme deficiency in Rajasthan (western-India). Haematologia (budap) 24:153–165

CAS  PubMed  Google Scholar 

Choubisa SL (2006) Erythrocyte mutant genes in inhabitants of arid-environment of Western Rajasthan (India). Indian J Phys Anthropol Hum Genet 25:15–30

Google Scholar 

Choubisa SL (2009) Sickle cell haemoglobin, thalassaemia and G-6-PD enzyme deficiency genes in Garasiya tribe inhabited malaria endemic areas of Sirohi District, Rajasthan (India). J Commun Dis 41:13–18

CAS  PubMed  Google Scholar 

Choubisa SL, Choubisa D, Choubisa L (2004) Erythrocyte genetic disorders in inhabitants of Aravali Hilly-Environment of Rajasthan (India). Indian J Phys Anthropol Hum Genet 23:145–159

Google Scholar 

Choudhuri S, Sen A, Ghosh MK, Misra S (2015) Effectiveness of prenatal screening for hemoglobinopathies in a developing country. Hemoglobin 39:380–383. https://doi.org/10.3109/03630269.2014.1003564

Article  CAS  PubMed  Google Scholar 

Colah R, Surve R, Wadia M, Solanki P, Mayekar P, Thomas M, Gorakshakar A, Dastur A, Mohanty D (2008) Carrier screening for β -thalassemia during pregnancy in India : a 7-year evaluation. Genet Test 12:181–186

Article  PubMed  Google Scholar 

Colah R, Gorakshakar A, Phanasgaonkar S, D’Souza E, Nadkarni A, Surve R, Sawant P, Master D, Patel R, Ghosh K, Mohanty D (2010) Epidemiology of β-thalassaemia in Western India: mapping the frequencies and mutations in sub-regions of Maharashtra and Gujarat. Br J Haematol 149:739–747. https://doi.org/10.1111/j.1365-2141.2010.08131.x

Article  CAS  PubMed  Google Scholar 

De M, Halder A, Podder S, Sen R, Chakrabarty S, Sengupta B, Chakraborty T, Das U, Talukder G (2006) Anemia and hemoglobinopathies in tribal population of Eastern and North-eastern India. Hematology 11:371–373. https://doi.org/10.1080/10245330600840180

Article  CAS  PubMed  Google Scholar 

Dolai TK, Dutta S, Bhattacharyya M, Ghosh MK (2012) Prevalence of hemoglobinopathies in rural Bengal, India. Hemoglobin 36:57–63

Article  CAS  PubMed  Google Scholar 

Gajra B, Chakraborti S, Sengupta B (2002) Prenatal Diagnosis of thalassaemias. Int J Hum Genet 2:173–178

Article  Google Scholar 

Galanello R, Origa R (2010) Beta-thalassemia. Orphanet J Rare Dis 5:1–15. https://doi.org/10.1186/1750-1172-5-11

Article  Google Scholar 

Ghosh K, Mukherjee MB, Shankar U, Kote SL, Nagtilak SB, Kolah RB, Surve RR, Tamankar AA, Sukumar S, Mohanty (2002) Clinical examination and hematological data in asymptomatic & apparently healthy school children in a boarding school in a tribal area. Indian J Public Health 46:61–65

CAS  PubMed  Google Scholar 

Gosavi M, Chavan R, Bellad MB (2021) NESTROFT—A Cost-Effective Mass Screening Tool for the Detection of β-Thalassemia Carrier Status in Anemic Pregnant Women: A Step Toward Reducing the National Disease Burden. J Lab Physicians 13:368–373. https://doi.org/10.1055/s-0041-1732493

Article  CAS  PubMed  PubMed Central  Google Scholar 

Gupta PK, Kumar H, Kumar S, Jaiprakash M (2009) Cation exchange high performance liquid chromatography for diagnosis of haemoglobinopathies. Med J Armed Forces India 65:33–37

Article  CAS  PubMed  Google Scholar 

Hickman M, Modell B, Greengross P, Chapman C, Layton M, Falconer S, Davies SC (1999) Mapping the prevalence of sickle cell and beta thalassaemia in England: estimating and validating ethnic-specific rates. Br J Haematol 104:860–867

Article  CAS  PubMed  Google Scholar 

International Committee for Standardization in Haematology (1978) Recommendations for selected methods for quantitative estimation of Hb A2 and for Hb A2 reference preparation. Br J Haematol 38:573–578

Article  Google Scholar 

Jain R, Mehta N, Joshi K, Gupta O, Andrew A (1981) Sickle cell trait, thalassemia and glucose-6-phosphate dehydrogenase deficiency in Bhil tribe of southern Rajasthan. Indian J Med Res 73:548–553

CAS  PubMed  Google Scholar 

Jain R, Andrew A, Choubisa SL (1983) Sickle cell & thalassaemic genes in the tribal population of Rajasthan. Indian J Med Res 78:836–840

CAS  PubMed  Google Scholar 

Jain BB, Roy RN, Ghosh S, Ghosh T, Banerjee U, Bhattacharya SK (2012) Screening for thalassemia and other hemoglobinopathies in a tertiary care hospital of West Bengal : implications for population screening. Indian J Public Health 56:297–300. https://doi.org/10.4103/0019-557X.106419

Article  PubMed  Google Scholar 

Jawahirani A, Mamtani M, Das K, Rughwani V, Kulkarni H (2007) Prevalence of beta-thalassaemia in subcastes of Indian Sindhis: Results from a two-phase survey. Public Health 121:193–198. https://doi.org/10.1016/j.puhe.2006.10.017

Article  CAS  PubMed  Google Scholar 

Kulkarni P, Masthi NRR, Niveditha S, Suvarna R (2013) The prevalence of the beta thalassemia trait among the pregnant women who attended the ANC Clinic in a PHC, by using the NESTROF test in Bangalore, Karnataka. J Clin Diagnostic Res 7:1414–1417. https://doi.org/10.7860/JCDR/2013/5286.3149

Article 

Comments (0)

No login
gif