Zhang X, Yang B, Li N, Li H. Prevalence and risk factors for erectile dysfunction in chinese adult males. J Sex Med. 2017;14:1201–8. https://doi.org/10.1016/j.jsxm.2017.08.009.

Article  PubMed  Google Scholar 

NIH Consensus Conference. Impotence. NIH consensus development panel on impotence. JAMA. 1993;270:83–90. https://doi.org/10.1001/jama.1993.03510010089036.

Article  Google Scholar 

McCabe MP, Sharlip ID, Lewis R, Atalla E, Balon R, Fisher AD, et al. Incidence and prevalence of sexual dysfunction in women and men: a consensus statement from the fourth international consultation on sexual medicine 2015. J Sex Med. 2016;13:144–52. https://doi.org/10.1016/j.jsxm.2015.12.034.

Article  PubMed  Google Scholar 

Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile Dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int. 1999;84:50–56. https://doi.org/10.1046/j.1464-410x.1999.00142.x.

Article  PubMed  Google Scholar 

Sheng Z. Psychological consequences of erectile dysfunction. Trends Urol Mens Health. 2021;12:19–22. https://doi.org/10.1002/tre.827.

Article  Google Scholar 

Delrue C, Speeckaert MM. Vitamin D and Vitamin D-binding protein in health and disease. Int J Mol Sci. 2023;24:4642 https://doi.org/10.3390/ijms24054642.

Article  PubMed  PubMed Central  Google Scholar 

DeLuca HF. Vitamin D endocrinology. Ann Intern Med. 1976;85:367–77. https://doi.org/10.7326/0003-4819-85-3-367.

Article  PubMed  Google Scholar 

Farag YMK, Guallar E, Zhao D, Kalyani RR, Blaha MJ, Feldman DI, et al. Vitamin D deficiency is independently associated with greater prevalence of erectile dysfunction: the national health and nutrition examination survey (NHANES) 2001-4. Atherosclerosis. 2016;252:61–67. https://doi.org/10.1016/j.atherosclerosis.2016.07.921.

Article  PubMed  PubMed Central  Google Scholar 

Horsanalı MO, Eren H, Dil E, Caglayan A, Erdogan O, Ekren F. Novel predictive risk factor of erectile dysfunction: Serum 25‐hydroxy vitamin D. Andrologia. 2020;52:e13767 https://doi.org/10.1111/and.13767.

Article  PubMed  Google Scholar 

Crafa A, Cannarella R, Condorelli RA, La Vignera S, Calogero AE. Is there an association between vitamin D deficiency and erectile dysfunction? a systematic review and meta-analysis. Nutrients. 2020;12:1411 https://doi.org/10.3390/nu12051411.

Article  PubMed  PubMed Central  Google Scholar 

Duarte Romero B, Waterhouse M, Baxter C, McLeod DSA, English DR, Armstrong BK, et al. The effect of three years of vitamin D supplementation on erectile dysfunction: results from the randomized placebo-controlled D-Health Trial. Clin Nutr ESPEN. 2024;60:109–15. https://doi.org/10.1016/j.clnesp.2024.01.011.

Article  PubMed  Google Scholar 

Elshahid AR, Zaky AM, Goda YMH, Ismail NF. Relationship between vitamin D receptors gene polymorphism and arteriogenic erectile dysfunction. Urologia. 2024;91:592–7. https://doi.org/10.1177/03915603241241430.

Article  PubMed  Google Scholar 

Crafa A, Cannarella R, Barbagallo F, Leanza C, Palazzolo R, Flores HA, et al. Mechanisms suggesting a relationship between vitamin D and erectile dysfunction: an overview. Biomolecules. 2023;13:930 https://doi.org/10.3390/biom13060930.

Article  PubMed  PubMed Central  Google Scholar 

Wang R, Zheng T, Zhang TB, Li R, Wang ZL, Yang F, et al. Efficacy and safety of sildenafil citrate in treatment of erectile dysfunction. Natl J Androl. 2019;25:603–7. https://doi.org/10.13263/j.cnki.nja.2019.07.005. Article in Chinese].

Article  Google Scholar 

Rosen RC, Cappelleri JC, Smith MD, Lipsky J, Peña BM. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res. 1999;11:319–26. https://doi.org/10.1038/sj.ijir.3900472.

Article  PubMed  Google Scholar 

Chinese Urological Association. Diagnosis and treatment guidelines for erectile dysfunction. Chin J Androl. 2022;28:722–55. https://doi.org/10.13263/j.cnki.nja.2022.08.009. Article in Chinese].

Article  Google Scholar 

Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab. 1999;84:3666–72. https://doi.org/10.1210/jcem.84.10.6079.

Article  PubMed  Google Scholar 

Rosen RC, Allen KR, Ni X, Araujo AB. Minimal clinically important differences in the erectile function domain of the international index of erectile function scale. Eur Urol. 2011;60:1010–6. https://doi.org/10.1016/j.eururo.2011.07.053.

Article  PubMed  Google Scholar 

Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011;96:1911–30. https://doi.org/10.1210/jc.2011-0385.

Article  PubMed  Google Scholar 

Portest S. A primer on model selection using the akaike information criterion. Infect Dis Model. 2020;5:111–28. https://doi.org/10.1016/j.idm.2019.12.010.

Article  Google Scholar 

Marrie RA, Dawson NV, Garland A. Quantile regression and restricted cubic splines are useful for exploring relationships between continuous variables. J Clin Epidemiol. 2009;62:511–.e1. https://doi.org/10.1016/j.jclinepi.2008.05.015.

Article  PubMed  Google Scholar 

MacDonald SM, Burnett AL. Physiology of erection and pathophysiology of erectile dysfunction. Urol Clin North Am. 2021;48:513–25. https://doi.org/10.1016/j.ucl.2021.06.009.

Article  PubMed  Google Scholar 

Toda N, Ayajiki K, Okamura T. Nitric oxide and penile erectile function. Pharmacol Ther. 2005;106:233–66. https://doi.org/10.1016/j.pharmthera.2004.11.011.

Article  PubMed  Google Scholar 

Andrukhova O, Slavic S, Zeitz U, Riesen SC, Heppelmann MS, Ambrisko TD, et al. Vitamin D is a regulator of endothelial nitric oxide synthase and arterial stiffness in mice. Mol Endocrinol. 2014;28:53–64. https://doi.org/10.1210/me.2013-1252.

Article  PubMed  Google Scholar 

Molinari C, Uberti F, Grossini E, Vacca G, Carda S, Invernizzi M, et al. 1α,25-Dihydroxycholecalciferol induces nitric oxide production in cultured endothelial cells. Cell Physiol Biochem. 2011;27:661–8. https://doi.org/10.1159/000330075.

Article  PubMed  Google Scholar 

Lin CS, Lin G, Xin ZC, Lue TF. Expression, distribution and regulation of phosphodiesterase 5. Curr Pharm Des. 2006;12:3439–57. https://doi.org/10.2174/138161206778343064.

Article  PubMed  Google Scholar 

Grossman E. The role of tadalafil in treated hypertensive patients with erectile dysfunction. J Clin Hypertens. 2022;24:182–3. https://doi.org/10.1111/jch.14434.

Article  Google Scholar 

Taskiran M, Dogan K. The efficacy of systemic inflammatory response and oxidative stress in erectile dysfunction through multi-inflammatory index: a prospective cross-sectional analysis. J Sex Med. 2023;20:591–6. https://doi.org/10.1093/jsxmed/qdad037.

Article  PubMed  Google Scholar 

Querfeld U. Vitamin D and inflammation. Pediatr Nephrol. 2013;28:605–10. https://doi.org/10.1007/s00467-012-2377-4.

Article  PubMed  Google Scholar 

De Vita F, Lauretani F, Bauer J, Bautmans I, Shardell M, Cherubini A, et al. Relationship between vitamin D and inflammatory markers in older individuals. Age. 2014;36:9694 https://doi.org/10.1007/s11357-014-9694-4.

Article  PubMed  PubMed Central  Google Scholar 

Defeudis G, Mazzilli R, Tenuta M, Rossini G, Zamponi V, Olana S, et al. Erectile dysfunction and diabetes: A melting pot of circumstances and treatments. Diabetes Metab Res Rev. 2021;38:e3494 https://doi.org/10.1002/dmrr.3494.

Article  PubMed  PubMed Central  Google Scholar 

Ma WJ, Qin M, Cui TW, Zhang XP, Ke ZH, Pan ZK, et al. Relationship between the risk factors of cardiovascular disease by testing biochemical markers and young men with erectile dysfunction: a case-control study. Transl Androl Urol. 2021;10:724 https://doi.org/10.21037/tau-20-1056.

Article  PubMed  PubMed Central