Atalayer, D., Pantazatos, S. P., Gibson, C. D., McOuatt, H., Puma, L., Astbury, N. M., & Geliebter, A. (2014). Sexually dimorphic functional connectivity in response to high vs. low energy-dense food cues in obese humans: An fMRI study. NeuroImage, 100, 405–413. https://doi.org/10.1016/j.neuroimage.2014.05.054
Babayan, A., Erbey, M., Kumral, D., Reinelt, J. D., Reiter, A. M. F., Röbbig, J., & Villringer, A. (2019). A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adults. Scientific Data, 6(1), 180308. https://doi.org/10.1038/sdata.2018.308
Article PubMed PubMed Central Google Scholar
Beyer, F., Kharabian Masouleh, S., Huntenburg, J. M., Lampe, L., Luck, T., Riedel-Heller, S. G., & Witte, A. V. (2017). Higher body mass index is associated with reduced posterior default mode connectivity in older adults. Human Brain Mapping, 38(7), 3502–3515. https://doi.org/10.1002/hbm.23605
Article PubMed PubMed Central Google Scholar
Brooks, S. J., Cedernaes, J., & Schiöth, H. B. (2013). Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: A meta-analysis of fMRI studies. PLoS One, 8(4), e60393. https://doi.org/10.1371/journal.pone.0060393
Article CAS PubMed PubMed Central Google Scholar
Cerit, H., Davidson, P., Hye, T., Moondra, P., Haimovici, F., Sogg, S., & Holsen, L. M. (2019). Resting-state brain connectivity predicts weight loss and cognitive control of eating behavior after vertical sleeve gastrectomy. Obesity (Silver Spring, Md.), 27(11), 1846–1855. https://doi.org/10.1002/oby.22607
Contreras-Rodríguez, O., Martín-Pérez, C., Vilar-López, R., & Verdejo-Garcia, A. (2017a). Ventral and dorsal striatum networks in obesity: Link to food craving and weight gain. Biological Psychiatry, 81(9), 789–796. https://doi.org/10.1016/j.biopsych.2015.11.020
Contreras-Rodríguez, O., Vilar-López, R., Andrews, Z. B., Navas, J. F., Soriano-Mas, C., & Verdejo-García, A. (2017b). Altered cross-talk between the hypothalamus and non-homeostatic regions linked to obesity and difficulty to lose weight. Scientific Reports, 7(1), 9951. https://doi.org/10.1038/s41598-017-09874-y
Article CAS PubMed PubMed Central Google Scholar
Coveleskie, K., Gupta, A., Kilpatrick, L. A., Mayer, E. D., Ashe-McNalley, C., Stains, J., & Mayer, E. A. (2015). Altered functional connectivity within the central reward network in overweight and obese women. Nutrition & Diabetes, 5, e148. https://doi.org/10.1038/nutd.2014.45
Ding, Y., Ji, G., Li, G., Zhang, W., Hu, Y., Liu, L., & Zhang, Y. (2020). Altered interactions among resting-state networks in individuals with obesity. Obesity (Silver Spring, Md.), 28(3), 601–608. https://doi.org/10.1002/oby.22731
Doucet, G. E., Rasgon, N., McEwen, B. S., Micali, N., & Frangou, S. (2017). Elevated body mass index is associated with increased integration and reduced cohesion of sensory-driven and internally guided resting-state functional brain networks. Cerebral Cortex, 28(3), 988–997. https://doi.org/10.1093/cercor/bhx008
Article PubMed Central Google Scholar
Faul, L., Fogleman, N. D., Mattingly, K. M., & Depue, B. E. (2019). Inhibitory control mediates a negative relationship between body mass index and intelligence: A neurocognitive investigation. Cognitive, Affective, & Behavioral Neuroscience, 19(2), 392–408. https://doi.org/10.3758/s13415-019-00695-2
Gupta, A., Mayer, E. A., Labus, J. S., Bhatt, R. R., Ju, T., Love, A., & Kilpatrick, L. A. (2018). Sex commonalities and differences in obesity-related alterations in intrinsic brain activity and connectivity. Obesity, 26(2), 340–350. https://doi.org/10.1002/oby.22060
Kahnt, T., Chang, L. J., Park, S. Q., Heinzle, J., & Haynes, J. D. (2012). Connectivity-based parcellation of the human orbitofrontal cortex. The Journal of Neuroscience, 32(18), 6240–6250.
Article CAS PubMed PubMed Central Google Scholar
Kullmann, S., Heni, M., Veit, R., Ketterer, C., Schick, F., Haering, H. U., & Preissl, H. (2012). The obese brain: Association of body mass index and insulin sensitivity with resting state network functional connectivity. Human Brain Mapping, 33(5), 1052–1061. https://doi.org/10.1002/hbm.21268
Kullmann, S., Pape, A. A., Heni, M., Ketterer, C., Schick, F., Häring, H. U., & Veit, R. (2013). Functional network connectivity underlying food processing: Disturbed salience and visual processing in overweight and obese adults. Cerebral Cortex, 23(5), 1247–1256. https://doi.org/10.1093/cercor/bhs124
Kullmann, S., Heni, M., Linder, K., Zipfel, S., Häring, H. U., Veit, R., & Preissl, H. (2014). Resting-state functional connectivity of the human hypothalamus. Human Brain Mapping, 35(12), 6088–6096. https://doi.org/10.1002/hbm.22607
Article PubMed PubMed Central Google Scholar
Liem, F., Varoquaux, G., Kynast, J., Beyer, F., Kharabian Masouleh, S., Huntenburg, J. M., & Margulies, D. S. (2017). Predicting brain-age from multimodal imaging data captures cognitive impairment. Neuroimage, 148, 179–188. https://doi.org/10.1016/j.neuroimage.2016.11.005
Lips, M. A., Wijngaarden, M. A., van der Grond, J., van Buchem, M. A., de Groot, G. H., Rombouts, S. A. R. B., & Veer, I. M. (2014). Resting-state functional connectivity of brain regions involved in cognitive control, motivation, and reward is enhanced in obese females1234. The American Journal of Clinical Nutrition, 100(2), 524–531. https://doi.org/10.3945/ajcn.113.080671
Article CAS PubMed Google Scholar
Maldjian, J. A., Laurienti, P. J., Kraft, R. A., & Burdette, J. H. (2003). An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets. Neuroimage, 19(3), 1233–1239. https://doi.org/10.1016/S1053-8119(03)00169-1
Menon, V. (2025). Insular cortex: A hub for saliency, cognitive control, and interoceptive awareness. In J. H. Grafman (Ed.), Encyclopedia of the human brain (Second Edition) (pp. 159–183). Elsevier.
Murphy, M. J. M., & Deutch, A. Y. (2018). Organization of afferents to the orbitofrontal cortex in the rat. Journal of Comparative Neurology, 526(9), 1498–1526. https://doi.org/10.1002/cne.24424
Nooner, K. B., Colcombe, S., Tobe, R., Mennes, M., Benedict, M., Moreno, A., & Milham, M. (2012). The NKI-Rockland sample: A model for accelerating the pace of discovery science in psychiatry. Frontiers in Neuroscience, 6, Article 152. https://doi.org/10.3389/fnins.2012.00152
Article PubMed PubMed Central Google Scholar
Park, B., Seo, J., Yi, J., & Park, H. (2015). Structural and functional brain connectivity of people with obesity and prediction of body mass index using connectivity. PLoS One, 10(11), Article e0141376. https://doi.org/10.1371/journal.pone.0141376
Article CAS PubMed PubMed Central Google Scholar
Rolls, E. T., Vatansever, D., Li, Y., Cheng, W., & Feng, J. (2020). Rapid rule-based reward reversal and the lateral orbitofrontal cortex. Cerebral Cortex Communications. https://doi.org/10.1093/texcom/tgaa087
Article PubMed PubMed Central Google Scholar
Rosenberg, M. D., Finn, E. S., Scheinost, D., Papademetris, X., Shen, X., Constable, R. T., & Chun, M. M. (2016). A neuromarker of sustained attention from whole-brain functional connectivity. Nature Neuroscience, 19(1), 165–171. https://doi.org/10.1038/nn.4179
Article CAS PubMed Google Scholar
Saruco, E., & Pleger, B. (2021). A systematic review of obesity and binge eating associated impairment of the cognitive inhibition system. Frontiers in Nutrition. https://doi.org/10.3389/fnut.2021.609012
Article PubMed PubMed Central Google Scholar
Scharnowski, F., Nicholson, A. A., Pichon, S., Rosa, M. J., Rey, G., Eickhoff, S. B., & Koush, Y. (2020). The role of the subgenual anterior cingulate cortex in dorsomedial prefrontal–amygdala neural circuitry during positive-social emotion regulation. Human Brain Mapping, 41(11), 3100–3118. https://doi.org/10.1002/hbm.25001
Article PubMed PubMed Central Google Scholar
Seabrook, L. T., & Borgland, S. L. (2020). The orbitofrontal cortex, food intake and obesity. Journal of Psychiatry & Neuroscience, 45(5), 304–312. https://doi.org/10.1503/jpn.190163
Seabrook, L. T., Naef, L., Baimel, C., Judge, A. K., Kenney, T., Ellis, M., & Borgland, S. L. (2023). Disinhibition of the orbitofrontal cortex biases decision-making in obesity. Nature Neuroscience, 26(1), 92–106. https://doi.org/10.1038/s41593-022-01210-6
Comments (0)