Agirman, G., Yu, K. B., & Hsiao, E. Y. (2021). Signaling inflammation across the gut-brain axis. Science, 374, 1087–1092.
Article CAS PubMed Google Scholar
Ahola, V., Saraste, M., Nylund, M., Matilainen, M., Luoma, A., Vuorimaa, A., Lehto, J., Laaksonen, S., Brockmann, E. C., Kuhle, J., Leppert, D., Soukka, T., Lamminmaki, U., & Airas, L. (2025). Plasma CHI3L1 associates with brain volume loss and glial activation in multiple sclerosis. Journal of Neurology, Neurosurgery and Psychiatry.
Barnes, P. J. (2018). Targeting cytokines to treat asthma and chronic obstructive pulmonary disease. Nature Reviews Immunology, 18, 454–466.
Article CAS PubMed Google Scholar
Bin, N. R., Prescott, S. L., Horio, N., Wang, Y., Chiu, I. M., & Liberles, S. D. (2023). An airway-to-brain sensory pathway mediates influenza-induced sickness. Nature, 615, 660–667.
Article CAS PubMed PubMed Central Google Scholar
Borovikova, L. V., Ivanova, S., Zhang, M., Yang, H., Botchkina, G. I., Watkins, L. R., Wang, H., Abumrad, N., Eaton, J. W., & Tracey, K. J. (2000). Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature, 405, 458–462.
Article CAS PubMed Google Scholar
Bowden, J., Davey, S. G., & Burgess, S. (2015). Mendelian randomization with invalid instruments: Effect estimation and bias detection through egger regression. International Journal of Epidemiology, 44, 512–525.
Article PubMed PubMed Central Google Scholar
Bowden, J., Del, G. M. F., Minelli, C., Davey, S. G., Sheehan, N., & Thompson, J. (2017). A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization. Statistics in Medicine, 36, 1783–1802.
Article PubMed PubMed Central Google Scholar
Brion, M. J., Shakhbazov, K., & Visscher, P. M. (2013). Calculating statistical power in Mendelian randomization studies. International Journal of Epidemiology, 42, 1497–1501.
Brouwer, R. M., Klein, M., Grasby, K. L., Schnack, H. G., Jahanshad, N., Teeuw, J., Thomopoulos, S. I., Sprooten, E., Franz, C. E., Gogtay, N., Kremen, W. S., Panizzon, M. S., Olde, L. L., Whelan, C. D., Aghajani, M., Alloza, C., Alnaes, D., Artiges, E., Ayesa-Arriola, R., … Hulshoff, P. M. (2022). PH genetic variants associated with longitudinal changes in brain structure across the lifespan. Nature Neuroscience, 25, 421–432.
Article CAS PubMed PubMed Central Google Scholar
Buckley, P. F. (2019). Neuroinflammation and schizophrenia. Current Psychiatry Reports, 21, Article 72.
Burdo, T. H., Robinson, J. A., Cooley, S., Smith, M. D., Flynn, J., Petersen, K. J., Nelson, B., Westerhaus, E., Wisch, J., & Ances, B. M. (2023). Increased peripheral inflammation is associated with structural brain changes and reduced blood flow in people with virologically controlled HIV. The Journal of Infectious Diseases, 228, 1071–1079.
Article PubMed PubMed Central Google Scholar
Channer, B., Matt, S. M., Nickoloff-Bybel, E. A., Pappa, V., Agarwal, Y., Wickman, J., & Gaskill, P. J. (2023). Dopamine, immunity, and disease. Pharmacological Reviews, 75, 62–158.
Article CAS PubMed PubMed Central Google Scholar
Cui, L. B., Wang, X. Y., Fu, Y. F., Liu, X. F., Wei, Y., Zhao, S. W., Gu, Y. W., Fan, J. W., Wu, W. J., Gong, H., Lin, B. D., Yin, H., Guan, F., & Chang, X. (2023). Transcriptional level of inflammation markers associates with short-term brain structural changes in first-episode schizophrenia. BMC Medicine, 21, Article 250.
Article CAS PubMed PubMed Central Google Scholar
Cusack, R. P., Whetstone, C. E., Xie, Y., Ranjbar, M., & Gauvreau, G. M. (2021). Regulation of eosinophilia in asthma-New therapeutic approaches for asthma treatment (p. 10). CELLS-BASEL.
Czapski, G. A., Cakala, M., Chalimoniuk, M., Gajkowska, B., & Strosznajder, J. B. (2007). Role of nitric oxide in the brain during lipopolysaccharide-evoked systemic inflammation. Journal of Neuroscience Research, 85, 1694–1703.
Article CAS PubMed Google Scholar
Czapski, G. A., Gajkowska, B., & Strosznajder, J. B. (2010). Systemic administration of lipopolysaccharide induces molecular and morphological alterations in the hippocampus. Brain Research, 1356, 85–94.
Article CAS PubMed Google Scholar
Davey, S. G., & Hemani, G. (2014). Mendelian randomization: Genetic anchors for causal inference in epidemiological studies. Human Molecular Genetics, 23, R89–R98.
Ebrahim, S., & Davey, S. G. (2008). Mendelian randomization: Can genetic epidemiology help redress the failures of observational epidemiology? Human Genetics, 123, 15–33.
Ezeomah, C., Cunningham, K. A., Stutz, S. J., Fox, R. G., Bukreyeva, N., Dineley, K. T., Paessler, S., & Cisneros, I. E. (2020). Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain, Behavior, and Immunity, 87, 725–738.
Article CAS PubMed Google Scholar
Flores-Martinez, Y. M., Fernandez-Parrilla, M. A., Ayala-Davila, J., Reyes-Corona, D., Blanco-Alvarez, V. M., Soto-Rojas, L. O., Luna-Herrera, C., Gonzalez-Barrios, J. A., Leon-Chavez, B. A., Gutierrez-Castillo, M. E., Martinez-Davila, I. A., & Martinez-Fong, D. (2018). Acute neuroinflammatory response in the substantia nigra pars compacta of rats after a local injection of lipopolysaccharide. Journal of Immunology Research, 2018, Article 1838921.
Article PubMed PubMed Central Google Scholar
Green, C., Shen, X., Stevenson, A. J., Conole, E., Harris, M. A., Barbu, M. C., Hawkins, E. L., Adams, M. J., Hillary, R. F., Lawrie, S. M., Evans, K. L., Walker, R. M., Morris, S. W., Porteous, D. J., Wardlaw, J. M., Steele, J. D., Waiter, G. D., Sandu, A. L., Campbell, A., … Whalley, H. C. (2021). Structural brain correlates of serum and epigenetic markers of inflammation in major depressive disorder. Brain, Behavior, and Immunity, 92, 39–48.
Article CAS PubMed PubMed Central Google Scholar
Gu, Y., Vorburger, R., Scarmeas, N., Luchsinger, J. A., Manly, J. J., Schupf, N., Mayeux, R., & Brickman, A. M. (2017). Circulating inflammatory biomarkers in relation to brain structural measurements in a non-demented elderly population. Brain, Behavior, and Immunity, 65, 150–160.
Article CAS PubMed PubMed Central Google Scholar
Hayek, D., Ziegler, G., Kleineidam, L., Brosseron, F., Nemali, A., Vockert, N., Ravichandran, K. A., Betts, M. J., Peters, O., Schneider, L. S., Wang, X., Priller, J., Altenstein, S., Schneider, A., Fliessbach, K., Wiltfang, J., Bartels, C., Rostamzadeh, A., Glanz, W., Buerger, K., Janowitz, D., Perneczky, R., Rauchmann, B. S., Teipel, S., Kilimann, I., Laske, C., Mengel, D., Synofzik, M., Munk, M. H., Spottke, A., Roy, N., Roeske, S., Kuhn, E., Ramirez, A., Dobisch, L., Schmid, M., Berger, M., Wolfsgruber, S., Yakupov, R., Hetzer, S., Dechent, P., Ewers, M., Scheffler, K., Schott, B. H., Schreiber, S., Orellana, A., de Rojas, I., Marquie, M., Boada, M., Sotolongo, O., Gonzalez, P. G., Puerta, R., Duzel, E., Jessen, F., Wagner, M., Ruiz, A., Heneka, M. T., & Maass, A. (2024). Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Molecular Psychiatry, 29, 992–1004.
Hemani, G., Zheng, J., Elsworth, B., Wade, K. H., Haberland, V., Baird, D., Laurin, C., Burgess, S., Bowden, J., Langdon, R., Tan, V. Y., Yarmolinsky, J., Shihab, H. A., Timpson, N. J., Evans, D. M., Relton, C., Martin, R. M., Davey, S. G., Gaunt, T. R., & Haycock, P. C. (2018). The MR-Base platform supports systematic causal inference across the human phenome. ELIFE 7.
Heming, N., Mazeraud, A., Verdonk, F., Bozza, F. A., Chretien, F., & Sharshar, T. (2017). Neuroanatomy of sepsis-associated encephalopathy. Critical Care, 21, 65.
Article PubMed PubMed Central Google Scholar
Hosseini, S., Wilk, E., Michaelsen-Preusse, K., Gerhauser, I., Baumgartner, W., Geffers, R., Schughart, K., & Korte, M. (2018). Long-term neuroinflammation induced by influenza A virus infection and the impact on hippocampal neuron morphology and function. The Journal of Neuroscience, 38, 3060–3080.
Article CAS PubMed PubMed Central Google Scholar
Ilanges, A., Shiao, R., Shaked, J., Luo, J. D., Yu, X., & Friedman, J. M. (2022). Brainstem ADCYAP1(+) neurons control multiple aspects of sickness behaviour. Nature, 609, 761–771.
Article CAS PubMed PubMed Central Google Scholar
Janowitz, D., Habes, M., Toledo, J. B., Hannemann, A., Frenzel, S., Terock, J., Davatzikos, C., Hoffmann, W., & Grabe, H. J. (2020). Inflammatory markers and imaging patterns of advanced brain aging in the general population. Brain Imaging and Behavior, 14, 1108–1117.
Article PubMed PubMed Central Google Scholar
Jin, H., Li, M., Jeong, E., Castro-Martinez, F., & Zuker, C. S. (2024). A body-brain circuit that regulates body inflammatory responses. Nature, 630, 695–703.
Comments (0)