A home-based model of hypertension care can lower blood pressure (BP) in patients with hypertension compared with standard care in the clinic, according to the IMPACT-BP trial. This trial was performed in a rural setting in South Africa and presented at the ESC Congress 2025. “When we take hypertension care out of the clinics, which are often far for patients, expensive to get to, overburdened and understaffed, we make health care convenient for patients, which can have major impacts on BP control,” says lead investigator Mark Siedner.

The trial included 774 adults with hypertension from public-sector clinics in a rural region of South Africa. The patients were randomly assigned to one of three groups: a home-based care model that included patient monitoring of BP, home visits by a community health worker (CHW) to collect data and deliver medication, and remote nurse-led decision-making supported by a mobile health application (CHW group); home-based care with the same elements but with BP readings transmitted automatically (enhanced-CHW group); or standard clinic-based care.