Xuan, C., Jin, C., Jin, Z. & Chi, Y. The protective effects of glutamine against bronchopulmonary dysplasia are associated with MKP-1/MAPK/cPLA2 signaling-mediated NF-kappaB pathway. Gen. Physiol. Biophys. 42, 229–239 (2023).
Zhu, Y. et al. ILC2 regulates hyperoxia-induced lung injury via an enhanced Th17 cell response in the BPD mouse model. BMC Pulm. Med. 23, 188 (2023).
PubMed PubMed Central CAS Google Scholar
Zhang, Q., Ran, X., He, Y., Ai, Q. & Shi, Y. Acetate downregulates the activation of NLRP3 inflammasomes and attenuates lung injury in neonatal mice with Bronchopulmonary Dysplasia. Front. Pediatr. 8, 595157 (2020).
Zhang, L. et al. Nesfatin-1 alleviates hyperoxia-induced bronchopulmonary dysplasia (BPD) via the nuclear factor-kappaB (NF-kappaB) p65 signaling pathway. J. Biochem. Mol. Toxicol. 38, e23680 (2024).
Yang, M., Chen, Y., Huang, X., Shen, F. & Meng, Y. ETS1 Ameliorates Hyperoxia-induced bronchopulmonary dysplasia in mice by activating Nrf2/HO-1 mediated ferroptosis. Lung 201, 425–441 (2023).
PubMed PubMed Central CAS Google Scholar
Zang, L. et al. SIRT3 improves alveolar epithelial cell damage caused by bronchopulmonary dysplasia through deacetylation of FOXO1. Allergol. Immunopathol.51, 191–204 (2023).
Cai, X. et al. GLP-1 treatment protects endothelial cells from oxidative stress-induced autophagy and endothelial dysfunction. Int. J. Biol. Sci. 14, 1696–1708 (2018).
PubMed PubMed Central CAS Google Scholar
Xia, J. et al. A GLP-1 analog liraglutide reduces intimal hyperplasia after coronary stent implantation via regulation of glycemic variability and NLRP3 Inflammasome/IL-10 signaling in diabetic swine. Front. Pharmacol. 11, 372 (2020).
PubMed PubMed Central CAS Google Scholar
Yu, X. et al. Liraglutide ameliorates non-alcoholic steatohepatitis by inhibiting NLRP3 inflammasome and pyroptosis activation via mitophagy. Eur. J. Pharmacol. 864, 172715 (2019).
Guo J. et al. Liraglutide alleviates sepsis-induced acute lung injury by regulating pulmonary surfactant through inhibiting autophagy. Immunopharmacol. Immunotoxicol. 2024:1–10.
Zhou, F., Zhang, Y., Chen, J., Hu, X. & Xu, Y. Liraglutide attenuates lipopolysaccharide-induced acute lung injury in mice. Eur. J. Pharmacol. 791, 735–740 (2016).
Dowell, J., Bice, Z., Yan, K. & Konduri, G. G. Hyperoxia-induced airflow restriction and Renin-Angiotensin System expression in a bronchopulmonary dysplasia mouse model. Physiol. Rep. 12, e15895 (2024).
PubMed PubMed Central CAS Google Scholar
Zhang, M., Gao, Y., Zhao, W., Yu, G. & Jin, F. ACE-2/ANG1-7 ameliorates ER stress-induced apoptosis in seawater aspiration-induced acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol. 315, L1015–L1027 (2018).
Meng, Y. et al. Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-kappaB pathway. Am. J. Respir. Cell Mol. Biol. 50, 723–736 (2014).
Liu, J. et al. Sini decoction alleviates E. coli induced acute lung injury in mice via equilibrating ACE-AngII-AT1R and ACE2-Ang-(1-7)-Mas axis. Life Sci. 208, 139–148 (2018).
Baer, B. et al. Liraglutide pretreatment attenuates sepsis-induced acute lung injury. Am. J. Physiol. Lung Cell Mol. Physiol. 325, L368–L384 (2023).
PubMed PubMed Central CAS Google Scholar
Lan, J. et al. Self-assembled miR-134-5p inhibitor nanoparticles ameliorate experimental bronchopulmonary dysplasia (BPD) via suppressing ferroptosis. Mikrochim. Acta 190, 491 (2023).
PubMed PubMed Central CAS Google Scholar
Zhou, W. et al. Glucagon-like peptide-1 receptor mediates the beneficial effect of liraglutide in an acute lung injury mouse model involving the thioredoxin-interacting protein. Am. J. Physiol. Endocrinol. Metab. 319, E568–E578 (2020).
PubMed PubMed Central CAS Google Scholar
Guo, J. et al. Liraglutide alleviates acute lung injury and mortality in Pneumonia-induced sepsis through regulating surfactant protein expression and secretion. Shock 61, 601–610 (2024).
Kua, K. P. & Lee, S. W. Systematic review and meta-analysis of clinical outcomes of early caffeine therapy in preterm neonates. Br. J. Clin. Pharmacol. 83, 180–191 (2017).
DeMauro, S. B. Neurodevelopmental outcomes of infants with bronchopulmonary dysplasia. Pediatr. Pulmonol. 56, 3509–3517 (2021).
Chen, Q. F. et al. Lipoxin A(4) attenuates LPS-induced acute lung injury via activation of the ACE2-Ang-(1-7)-Mas axis. Innate Immun. 24, 285–296 (2018).
PubMed PubMed Central CAS Google Scholar
Gao, Y. L. et al. Role of Renin-Angiotensin system in acute lung injury caused by viral infection. Infect. Drug Resist. 13, 3715–3725 (2020).
PubMed PubMed Central CAS Google Scholar
He, Y. et al. ACE2 improves endothelial cell function and reduces acute lung injury by downregulating FAK expression. Int. Immunopharmacol. 128, 111535 (2024).
Fandino, J. et al. Liraglutide enhances the activity of the ACE-2/Ang(1-7)/Mas Receptor pathway in lungs of male pups from food-restricted mothers and prevents the reduction of SP-A. Int. J. Endocrinol. 2018, 6920620 (2018).
PubMed PubMed Central CAS Google Scholar
Wu, Y., Yang, X., Ju, Y. & Zhao, F. Fraxinol attenuates LPS-induced acute lung injury by equilibrating ACE-Ang II-AT1R and ACE2-Ang (1-7)-Mas and inhibiting NLRP3. Pharm. Biol. 60, 979–989 (2022).
PubMed PubMed Central CAS Google Scholar
Meng, Y. et al. The angiotensin-converting enzyme 2/angiotensin (1-7)/Mas axis protects against lung fibroblast migration and lung fibrosis by inhibiting the NOX4-derived ROS-mediated RhoA/Rho kinase pathway. Antioxid. Redox Signal. 22, 241–258 (2015).
PubMed PubMed Central CAS Google Scholar
Li, R. J., Wu, C. Y., Ke, H. L., Wang, X. P. & Zhang, Y. W. Qing Fei Hua Xian Decoction ameliorates bleomycin-induced pulmonary fibrosis by suppressing oxidative stress through balancing ACE-AngII-AT1R/ACE2-Ang-(1-7)-Mas axis. Iran. J. Basic Med. Sci. 26, 107–113 (2023).
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