J.M. Webster, C.G. Fenton, R. Langen, R.S. Hardy, Exploring the interface between inflammatory and therapeutic glucocorticoid induced bone and muscle loss. Int. J. Mol. Sci. 20, 5768 (2019). https://doi.org/10.3390/ijms20225768

Article  CAS  PubMed  PubMed Central  Google Scholar 

G. Mazziotti, A. Angeli, J.P. Bilezikian, E. Canalis, A. Giustina, Glucocorticoid-induced osteoporosis: an update. Trends Endocrinol. Metab. 17, 144–149 (2006). https://doi.org/10.1016/j.tem.2006.03.009

Article  CAS  PubMed  Google Scholar 

G. Mazziotti, A. Giustina, E. Canalis, J.P. Bilezikian, Glucocorticoid-induced osteoporosis: clinical and therapeutic aspects. Arq. Bras. Endocrinol. Metabol. 51, 1404–1412 (2007). https://doi.org/10.1590/s0004-27302007000800028

Article  PubMed  Google Scholar 

S. Pal, N. Mittapelly, A. Husain, S. Kushwaha, S. Chattopadhyay, P. Kumar, E. Ramakrishna, S. Kumar, R. Maurya, S. Sanyal, J.R. Gayen, P.R. Mishra, N. Chattopadhyay, A butanolic fraction from the standardized stem extract of Cassia occidentalis L delivered by a self-emulsifying drug delivery system protects rats from glucocorticoid-induced osteopenia and muscle atrophy. Sci. Rep. 10, 195 (2020). https://doi.org/10.1038/s41598-019-56853-6

Article  CAS  PubMed  PubMed Central  Google Scholar 

M. Arazzi, G. Di Fulvio Di, L.O. Pietro, X. Grabocka, M.O. Longo, G. Micioni, A. Pezzutto, L. Piscitani, A. Schiazza, S. Silvestri, G. Vigilante, L. Amoroso, M. Bonomini, [Therapy of glucocorticoid induced osteoporosis]. Giornale italiano di nefrologia: organo ufficiale della Societa italiana di nefrologia. 34, (2017).

S. Pal, P. Kumar, E. Ramakrishna, S. Kumar, K. Porwal, B. Kumar, K.R. Arya, R. Maurya, N. Chattopadhyay, Extract and fraction of Cassia occidentalis L. (a synonym of Senna occidentalis) have osteogenic effect and prevent glucocorticoid-induced osteopenia. J. Ethnopharmacol. 235, 8–18 (2019). https://doi.org/10.1016/j.jep.2019.01.029

Article  CAS  PubMed  Google Scholar 

G. Russow, D. Jahn, J. Appelt, S. Märdian, S. Tsitsilonis, J. Keller, Anabolic therapies in osteoporosis and bone regeneration. Int. J. Mol. Sci. 20, 83 (2018). https://doi.org/10.3390/ijms20010083

Article  CAS  PubMed  PubMed Central  Google Scholar 

S. Pal, S. Sharma, K. Porwal, M. Riyazuddin, C. Kulkarni, S. Chattopadhyay, S. Sanyal, J.R. Gayen, N. Chattopadhyay, Oral administration of isovitexin, a naturally occurring apigenin derivative showed osteoanabolic effect in ovariectomized mice: a comparative study with teriparatide. Calcif. Tissue Int. 111, 196–210 (2022). https://doi.org/10.1007/s00223-022-00979-9

Article  CAS  PubMed  Google Scholar 

S.P. China, S. Pal, S. Chattopadhyay, K. Porwal, S. Kushwaha, S. Bhattacharyya, M. Mittal, A.A. Gurjar, T. Barbhuyan, A.K. Singh, A.K. Trivedi, J.R. Gayen, S. Sanyal, N. Chattopadhyay, Globular adiponectin reverses osteo-sarcopenia and altered body composition in ovariectomized rats. Bone 105, 75–86 (2017). https://doi.org/10.1016/j.bone.2017.08.005

Article  CAS  PubMed  Google Scholar 

S. Rajput, C. Kulkarni, S. Sharma, M.S. Tomar, S. Khatoon, A. Gupta, S. Sanyal, A. Shrivastava, J.K. Ghosh, N. Chattopadhyay, Osteogenic effect of an adiponectin-derived short peptide that rebalances bone remodeling: a potential disease-modifying approach for postmenopausal osteoporosis therapy. Arch. Pharmacal. Res. 47, 736–755 (2024). https://doi.org/10.1007/s12272-024-01509-x

Article  CAS  Google Scholar 

M. Okada-Iwabu, T. Yamauchi, M. Iwabu, T. Honma, K. Hamagami, K. Matsuda, M. Yamaguchi, H. Tanabe, T. Kimura-Someya, M. Shirouzu, H. Ogata, K. Tokuyama, K. Ueki, T. Nagano, A. Tanaka, S. Yokoyama, T. Kadowaki, A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity. Nature 503, 493–499 (2013). https://doi.org/10.1038/nature12656

Article  CAS  PubMed  Google Scholar 

S.K. Choi, Y. Kwon, S. Byeon, C.E. Haam, Y.H. Lee, AdipoRon, adiponectin receptor agonist, improves vascular function in the mesenteric arteries of type 2 diabetic mice. PLoS One 15, e0230227 (2020). https://doi.org/10.1371/journal.pone.0230227

Article  CAS  PubMed  PubMed Central  Google Scholar 

A.K. Singh, A.A. Joharapurkar, M.P. Khan, J.S. Mishra, N. Singh, M. Yadav, Z. Hossain, K. Khan, S. Kumar, N.A. Dhanesha, D.P. Mishra, R. Maurya, S. Sharma, M.R. Jain, A.K. Trivedi, M.M. Godbole, J.R. Gayen, N. Chattopadhyay, S. Sanyal, Orally active osteoanabolic agent GTDF binds to adiponectin receptors, with a preference for AdipoR1, induces adiponectin-associated signaling, and improves metabolic health in a rodent model of diabetes. Diabetes 63, 3530–3544 (2014). https://doi.org/10.2337/db13-1619

Article  CAS  PubMed  Google Scholar 

A.K. Singh, S. Shree, S. Chattopadhyay, S. Kumar, A. Gurjar, S. Kushwaha, H. Kumar, A.K. Trivedi, N. Chattopadhyay, R. Maurya, R. Ramachandran, S. Sanyal, Small molecule adiponectin receptor agonist GTDF protects against skeletal muscle atrophy. Mol. Cell. Endocrinol. 439, 273–285 (2017). https://doi.org/10.1016/j.mce.2016.09.013

Article  CAS  PubMed  Google Scholar 

S. Pal, M. Singh, K. Porwal, S. Rajak, N. Das, S. Rajput, A.K. Trivedi, R. Maurya, R.A. Sinha, M.I. Siddiqi, S. Sanyal, N. Chattopadhyay, Adiponectin receptors by increasing mitochondrial biogenesis and respiration promote osteoblast differentiation: Discovery of isovitexin as a new class of small molecule adiponectin receptor modulator with potential osteoanabolic function. Eur. J. Pharmacol. 913, 174634 (2021). https://doi.org/10.1016/j.ejphar.2021.174634

Article  CAS  PubMed  Google Scholar 

S. Khatoon, N. Das, S. Chattopadhyay, A. Joharapurkar, A. Singh, V. Patel, A. Nirwan, A. Kumar, M.N. Mugale, D.P. Mishra, J. Kumaravelu, R. Guha, M.R. Jain, N. Chattopadhyay, S. Sanyal, Apigenin-6-C-glucoside ameliorates MASLD in rodent models via selective agonism of adiponectin receptor 2. Eur. J. Pharmacol. 978, 176800 (2024). https://doi.org/10.1016/j.ejphar.2024.176800

Article  CAS  PubMed  Google Scholar 

D. Hou, L. Yousaf, Y. Xue, J. Hu, J. Wu, X. Hu, N. Feng, Q. Shen, Mung Bean (Vigna radiata L.): bioactive polyphenols, polysaccharides, peptides, and health benefits. Nutrients 11, 1238 (2019). https://doi.org/10.3390/nu11061238

Article  CAS  PubMed  PubMed Central  Google Scholar 

J.P. Kalinová, N. Vrchotová, J. Tříska, Vitexin and isovitexin levels in sprouts of selected plants. J. Food Composition Anal. 100, 103895 (2021)

Article  Google Scholar 

S. Khole, S. Chatterjee, P. Variyar, A. Sharma, T. Devasagayam, S. Ghaskadbi, Bioactive constituents of germinated fenugreek seeds with strong antioxidant potential. J. Funct. Foods 6, 270–279 (2014)

Article  CAS  Google Scholar 

L.F. Laurindo, S.M. Barbalho, A.C. Araújo, E.L. Guiguer, A. Mondal, G. Bachtel, A. Bishayee, Açaí (Euterpe oleracea Mart.) in health and disease: a critical review. Nutrients 15, 989 (2023). https://doi.org/10.3390/nu15040989

Article  CAS  PubMed  PubMed Central  Google Scholar 

T. Rho, M.S. Choi, M. Jung, H.W. Kil, Y.D. Hong, K.D. Yoon, Identification of fermented tea (Camellia sinensis) polyphenols and their inhibitory activities against amyloid-beta aggregation. Phytochemistry 160, 11–18 (2019). https://doi.org/10.1016/j.phytochem.2018.12.013

Article  CAS  PubMed  Google Scholar 

C. Kulkarni, S. Sharma, P.S. Bora, S. Verma, S. Rajput, K. Porwal, S.K. Rath, J.R. Gayen, U. Sharma, N. Chattopadhyay, A novel extraction method enhanced the osteogenic and anti-osteoporosis effect of tea extract without any hepatotoxicity in ovariectomized rats. Front. Endocrinol. 13, 951800 (2022). https://doi.org/10.3389/fendo.2022.951800

Article  Google Scholar 

K. Porwal, S. Pal, C. Kulkarni, P. Singh, S. Sharma, P. Singh, G. Prajapati, J.R. Gayen, R.S. Ampapathi, A. Mullick, N. Chattopadhyay, A prebiotic, short-chain fructo-oligosaccharides promotes peak bone mass and maintains bone mass in ovariectomized rats by an osteogenic mechanism. Biomed. Pharmacother. 129, 110448 (2020). https://doi.org/10.1016/j.biopha.2020.110448

Article  CAS  PubMed  Google Scholar 

C. Kulkarni, S. Sharma, K. Porwal, S. Rajput, S. Sadhukhan, V. Singh, A. Singh, S. Baranwal, S. Kumar, A. Girme, A.R. Pandey, S.P. Singh, K.V. Sashidhara, N. Kumar, L. Hingorani, N. Chattopadhyay, A standardized extract of Coleus forskohlii root protects rats from ovariectomy-induced loss of bone mass and strength, and impaired bone material by osteogenic and anti-resorptive mechanisms. Front. Endocrinol. 14, 1130003 (2023). https://doi.org/10.3389/fendo.2023.1130003

Article  Google Scholar 

P. Sihota, R.N. Yadav, R. Dhaliwal, J.C. Bose, V. Dhiman, D. Neradi, S. Karn, S. Sharma, S. Aggarwal, V.G. Goni, V. Mehandia, D. Vashishth, S.K. Bhadada, N. Kumar, Investigation of mechanical, material, and compositional determinants of human trabecular bone quality in type 2 diabetes. J. Clin. Endocrinol. Metab. 106, e2271–e2289 (2021). https://doi.org/10.1210/clinem/dgab027

Article  PubMed  Google Scholar 

K. Porwal, S. Sharma, S. Kumar, M.S. Tomar, S. Sadhukhan, S. Rajput, C. Kulkarni, A. Shrivastava, N. Kumar, N. Chattopadhyay, Hormonal and non-hormonal oral contraceptives given long-term to pubertal rats differently affect bone mass, quality and metabolism. Front. Endocrinol. 14, 1233613 (2023). https://doi.org/10.3389/fendo.2023.1233613

Article  Google Scholar 

K.R. Washimkar, M.S. Tomar, S. Ishteyaque, A. Kumar, A. Shrivastava, M.N. Mugale, Benzo[a]pyrene treatment modulates Nrf2/Keap1 axis and changes the metabolic profile in rat lung cancer. Chemico-Biological Interact. 373, 110373 (2023). https://doi.org/10.1016/j.cbi.2023.110373

Article