Parathyroid weight estimation: beyond ellipsoid volume

A. Siperstein, E. Berber, G.F. Barbosa et al., Predicting the success of limited exploration for primary hyperparathyroidism using ultrasound, sestamibi, and intraoperative parathyroid hormone: analysis of 1158 cases. Ann. Surg. 248, 420–428 (2008). https://doi.org/10.1097/SLA.0b013e3181859f71.

Article  PubMed  Google Scholar 

R. Yeh, Y.D. Tay, L. Dercle, L. Bandeira, M.R. Parekh, J.P. Bilezikian, A simple formula to estimate parathyroid weight on 4D-CT, predict pathologic weight, and diagnose parathyroid adenoma in patients with primary hyperparathyroidism. AJNR Am. J. Neuroradiol. 41, 1690–1697 (2020). https://doi.org/10.3174/ajnr.A6687.

Article  CAS  PubMed  PubMed Central  Google Scholar 

S. Mori, Parenchymal weight of the parathyroid gland and the kidney in chronic glomerulonephritis. Tohoku J. Exp. Med. 125, 85–91 (1978). https://doi.org/10.1620/tjem.125.85.

Article  CAS  PubMed  Google Scholar 

G. Akerstrom, L. Grimelius, H. Johansson, H. Lundqvist, Estimation of the parenchymal-cell content of the parathyroid gland, using density-gradient columns. Preliminary report. Acta Pathol. Microbiol. Scand. A 85, 555–557 (1977). https://doi.org/10.1111/j.1699-0463.1977.tb03888.x.

Article  CAS  PubMed  Google Scholar 

C.A. Wang, S.V. Rieder, A density test for the intraoperative differentiation of parathyroid hyperplasia from neoplasia. Ann. Surg. 187, 63–67 (1978).

Article  CAS  PubMed  PubMed Central  Google Scholar 

L. Grimelius, L. Bondeson, Histopathological diagnosis of parathyroid diseases. Pathol. Res. Pract. 191, 353–365 (1995). https://doi.org/10.1016/S0344-0338(11)80889-7.

Article  CAS  PubMed  Google Scholar 

L. Grimelius, G. Akerstrom, H. Johansson, H. Lundqvist, Estimation of parenchymal cell content of human parathyroid glands using the image analyzing computer technique. Am. J. Pathol. 93, 793–800 (1978).

CAS  PubMed  PubMed Central  Google Scholar 

J.W. Kunstman, J.D. Kirsch, A. Mahajan, R. Udelsman, Clinical review: parathyroid localization and implications for clinical management. J. Clin. Endocrinol. Metab. 98, 902–912 (2013). https://doi.org/10.1210/jc.2012-3168.

Article  CAS  PubMed  Google Scholar 

R. Naples, J.D. Thomas, R. Monteiro et al., Preoperative calcium and parathyroid hormone values are poor predictors of gland volume and multigland disease in primary hyperparathyroidism: a review of 2000 consecutive patients. Endocr. Pract. 28, 77–82 (2022). https://doi.org/10.1016/j.eprac.2021.08.003.

Article  PubMed  Google Scholar 

V. Bindlish, J.L. Freeman, I.J. Witterick, S.L. Asa, Correlation of biochemical parameters with single parathyroid adenoma weight and volume. Head. Neck 24, 1000–1003 (2002). https://doi.org/10.1002/hed.10165.

Article  PubMed  Google Scholar 

M. Milas, K. Wagner, K.A. Easley, A. Siperstein, C.J. Weber, Double adenomas revisited: nonuniform distribution favors enlarged superior parathyroids (fourth pouch disease). Surgery 134, 995–1003 (2003). https://doi.org/10.1016/j.surg.2003.07.009.

Article  PubMed  Google Scholar 

J. Kirkby-Bott, Z. El-Khatib, B. Soudan, R. Caiazzo, L. Arnalsteen, B. Carnaille, 25-hydroxy vitamin D deficiency causes parathyroid incidentalomas. Langenbecks Arch. Surg. 395, 919–924 (2010). https://doi.org/10.1007/s00423-010-0692-4.

Article  PubMed  Google Scholar 

E. Rezkallah, A. Elsaify, R. Hanna, W. Elsaify, Correlation between preoperative calcium and parathormone levels with parathyroid gland volume. Endocr. Regul. 57, 12–17 (2023). https://doi.org/10.2478/enr-2023-0002.

Article  PubMed  Google Scholar 

C. Dubost, P.J. Bordier, J. Ferry, J. Gueris, The estimation of parathormone in primary hyperparathyroidism (author’s transl). Nouv. Presse Med. 7, 21–25 (1978).

CAS  PubMed  Google Scholar 

P.K. Wagner, M. Rothmund, Correlation of tumor weight and typical pathologic laboratory parameters in primary and secondary hyperparathyroidism. Langenbecks Arch. Chir. 360, 133–139 (1983). https://doi.org/10.1007/bf01254921.

Article  CAS  PubMed  Google Scholar 

R. Rutledge, M. Stiegel, C.G. Thomas Jr., R.E. Wild, The relation of serum calcium and immunoparathormone levels to parathyroid size and weight in primary hyperparathyroidism. Surgery 98, 1107–1112 (1985).

CAS  PubMed  Google Scholar 

G. Hedbäck, A. Odén, L.E. Tisell, Parathyroid adenoma weight and the risk of death after treatment for primary hyperparathyroidism. Surgery 117, 134–139 (1995). https://doi.org/10.1016/s0039-6060(05)80076-5.

Article  PubMed  Google Scholar 

P.S. Randhawa, A.D. Mace, S.A. Nouraei, M.P. Stearns, Primary hyperparathyroidism: do perioperative biochemical variables correlate with parathyroid adenoma weight or volume?. Clin. Otolaryngol. 32, 179–184 (2007). https://doi.org/10.1111/j.1365-2273.2007.01447.x.

Article  CAS  PubMed  Google Scholar 

J.G. Williams, M.H. Wheeler, J.P. Aston, R.C. Brown, J.S. Woodhead, The relationship between adenoma weight and intact (1–84) parathyroid hormone level in primary hyperparathyroidism. Am. J. Surg. 163, 301–304 (1992). https://doi.org/10.1016/0002-9610(92)90007-e.

Article  CAS  PubMed  Google Scholar 

P.A. Harris, R. Taylor, B.L. Minor et al., The REDCap consortium: building an international community of software partners. J. Biomed. Inf. 95, 103208 (2019). https://doi.org/10.1016/j.jbi.2019.103208.

Article  Google Scholar 

P. Bankhead, M.B. Loughrey, J.A. Fernández et al., QuPath: open source software for digital pathology image analysis. Sci. Rep. 7, 16878 (2017). https://doi.org/10.1038/s41598-017-17204-5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

H. Wickham, M. Averick, J. Bryan et al., Welcome to the tidyverse. J. Open. Source Softw. 4, 1686 (2019).

Article  Google Scholar 

H. Wickham, in ggplot2: Elegant Graphics for Data Analysis (Springer-Verlag, New York, 2016).

Book  Google Scholar 

D. Gohel, P. Skintzos, flextable: Functions for tabular reporting. Secondary Flextable: Functions for Tabular Reporting (2023). Accessed 1/12/2025. https://CRAN.R-project.org/package=flextable.

D. Gohel, officer: Manipulation of microsoft word and powerpoint documents. Secondary Officer: Manipulation of Microsoft Word and Powerpoint Documents (2023). Accessed 1/12/2025. https://CRAN.R-project.org/package=officer.

W. Chang, J. Cheng, J. Allaire, et al, shiny: Web Application Framework for R. Secondary shiny: Web Application Framework for R (2024). Accessed 1/12/2025. https://github.com/rstudio/shiny, https://shiny.posit.co/.

G. Akerström, L. Grimelius, H. Johansson, H. Pertoft, H. Lundqvist, Estimation of the parathyroid parenchymal cell mass by density gradients. Am. J. Pathol. 99, 685–694 (1980).

PubMed  PubMed Central  Google Scholar 

K.R. Anderson, B.H. Heidinger, Y. Chen, A.A. Bankier, P.A. VanderLaan, Measurement bias of gross pathologic compared with radiologic tumor size of resected lung adenocarcinomas: implications for the T-stage revisions in the eighth edition of the American joint committee on cancer staging manual. Am. J. Clin. Pathol. 147, 641–648 (2017). https://doi.org/10.1093/ajcp/aqx036.

Article  PubMed  Google Scholar 

B. Behjatnia, J. Sim, L.W. Bassett, N.A. Moatamed, S.K. Apple, Does size matter? comparison study between MRI, gross, and microscopic tumor sizes in breast cancer in lumpectomy specimens. Int. J. Clin. Exp. Pathol. 3, 303–309 (2010).

PubMed  PubMed Central  Google Scholar 

B.H. Yeap, S. Muniandy, S.K. Lee, S. Sabaratnam, M. Singh, Specimen shrinkage and its influence on margin assessment in breast cancer. Asian J. Surg. 30, 183–187 (2007). https://doi.org/10.1016/s1015-9584(08)60020-2.

Article  PubMed  Google Scholar 

K.A. Baugh, L. Yip, K.M. Ramonell, S.E. Carty, K.L. McCoy, Outcomes of subtotal parathyroidectomy for renal hyperparathyroidism. Surgery 175, 788–793 (2024). https://doi.org/10.1016/j.surg.2023.09.016.

Article  PubMed  Google Scholar 

S. Kurtom, S.E. Carty, Primary hyperparathyroidism: part two: surgical management. Surg. Clin. North. Am. 104, 799–809 (2024). https://doi.org/10.1016/j.suc.2024.02.009.

Article  PubMed  Google Scholar 

S.E. Rodgers, S.E. Carty, Primary hyperparathyroidism. In Fischer’s Mastery of Surgery: E.C. Ellison, G.R. Upchurch, (eds.), 8th ed (2023).

S.H. You, S.I. Suh, I.S. Ryoo et al., Assessing the accuracy and reliability of ultrasonographic three-dimensional parathyroid volume measurement in a patient with secondary hyperparathyroidism: a comparison with the two-dimensional conventional method. Ultrasonography 36, 17–24 (2017). https://doi.org/10.14366/usg.16022.

Article  PubMed 

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