Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018;7:1535750. https://doi.org/10.1080/20013078.2018.1535750.
Article PubMed PubMed Central Google Scholar
Caby M-P, Lankar D, Vincendeau-Scherrer C, Raposo G, Bonnerot C. Exosomal-like vesicles are present in human blood plasma. Int Immunol. 2005;17:879–87. https://doi.org/10.1093/intimm/dxh267.
Article CAS PubMed Google Scholar
Pisitkun T, Shen R-F, Knepper MA. Identification and proteomic profiling of exosomes in human urine. Proc Natl Acad Sci USA. 2004;101:13368–73. https://doi.org/10.1073/pnas.0403453101.
Article CAS PubMed PubMed Central Google Scholar
Colombo M, Raposo G, Théry C. Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. Annu Rev Cell Dev Biol. 2014;30:255–89. https://doi.org/10.1146/annurev-cellbio-101512-122326.
Article CAS PubMed Google Scholar
Liu A, Hefley B, Escandon P, Nicholas SE, Karamichos D. Salivary exosomes in health and disease: future prospects in the eye. Int J Mol Sci. 2023;24:6363. https://doi.org/10.3390/ijms24076363.
Article CAS PubMed PubMed Central Google Scholar
Vallabhajosyula P, Korutla L, Habertheuer A, Reddy S, Schaufler C, Lasky J, et al. Ex vivo lung perfusion model to study pulmonary tissue extracellular microvesicle profiles. Ann Thorac Surg. 2017;103:1758–66. https://doi.org/10.1016/j.athoracsur.2016.11.074.
Article PubMed PubMed Central Google Scholar
Eapen MS, Hansbro PM, Larsson-Callerfelt A-K, Jolly MK, Myers S, Sharma P, et al. Chronic obstructive pulmonary disease and lung cancer: underlying pathophysiology and new therapeutic modalities. Drugs. 2018;78:1717–40. https://doi.org/10.1007/s40265-018-1001-8.
Woud WW, Merino A, Hoogduijn MJ, Boer K, van den Hoogen MWF, Baan CC, et al. Nanoparticle release by extended criteria donor kidneys during normothermic machine perfusion. Transplantation. 2019;103: e110. https://doi.org/10.1097/TP.0000000000002642.
Woud WW, Arykbaeva AS, Alwayn IPJ, Baan CC, Minnee RC, Hoogduijn MJ, et al. Extracellular vesicles released during normothermic machine perfusion are associated with human donor kidney characteristics. Transplantation. 2022;106:2360–9. https://doi.org/10.1097/TP.0000000000004215.
Article CAS PubMed PubMed Central Google Scholar
Ma L, Li Y, Peng J, Wu D, Zhao X, Cui Y, et al. Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration. Cell Res. 2015;25:24–38. https://doi.org/10.1038/cr.2014.135.
Article CAS PubMed Google Scholar
Rawal SU, Patel BM, Patel MM. New drug delivery systems developed for brain targeting. Drugs. 2022;82:749–92. https://doi.org/10.1007/s40265-022-01717-z.
Article CAS PubMed Google Scholar
Buzas EI. The roles of extracellular vesicles in the immune system. Nat Rev Immunol. 2023;23:236–50. https://doi.org/10.1038/s41577-022-00763-8.
Article CAS PubMed Google Scholar
Bansal S, Rahman M, Ravichandran R, Canez J, Fleming T, Mohanakumar T. Extracellular vesicles in transplantation: friend or foe. Transplantation. 2024;108:374. https://doi.org/10.1097/TP.0000000000004693.
Del Vecchio L, Allinovi M, Comolli S, Peiti S, Rimoldi C, Locatelli F. Drugs in development to treat IgA nephropathy. Drugs. 2024;84:503–25. https://doi.org/10.1007/s40265-024-02036-1.
Article CAS PubMed Google Scholar
Duneton C, Winterberg PD, Ford ML. Activation and regulation of alloreactive T cell immunity in solid organ transplantation. Nat Rev Nephrol. 2022;18:663–76. https://doi.org/10.1038/s41581-022-00600-0.
Article CAS PubMed PubMed Central Google Scholar
Marino J, Babiker-Mohamed MH, Crosby-Bertorini P, Paster JT, LeGuern C, Germana S, et al. Donor exosomes rather than passenger leukocytes initiate alloreactive T cell responses after transplantation. Sci Immunol. 2016;1:aaf8759. https://doi.org/10.1126/sciimmunol.aaf8759.
Article PubMed PubMed Central Google Scholar
Liu Q, Rojas-Canales DM, Divito SJ, Shufesky WJ, Stolz DB, Erdos G, et al. Donor dendritic cell–derived exosomes promote allograft-targeting immune response. J Clin Invest. 2016;126:2805–20. https://doi.org/10.1172/JCI84577.
Article PubMed PubMed Central Google Scholar
Wahlgren J, Karlson TDL, Glader P, Telemo E, Valadi H. Activated human T cells secrete exosomes that participate in IL-2 mediated immune response signaling. PLoS ONE. 2012;7: e49723. https://doi.org/10.1371/journal.pone.0049723.
Article CAS PubMed PubMed Central Google Scholar
Cui B, Chen X-J, Sun J, Li S-P, Zhou G-P, Sun L-Y, et al. Dendritic cells originating exosomal miR-193b-3p induces regulatory T cells to alleviate liver transplant rejection. Int Immunopharmacol. 2023;114: 109541. https://doi.org/10.1016/j.intimp.2022.109541.
Article CAS PubMed Google Scholar
Sigdel TK, Ng YW, Lee S, Nicora CD, Qian W-J, Smith RD, et al. Perturbations in the urinary exosome in transplant rejection. Front Med (Lausanne). 2015;1:57. https://doi.org/10.3389/fmed.2014.00057.
Lim J-H, Lee C-H, Kim KY, Jung H-Y, Choi J-Y, Cho J-H, et al. Novel urinary exosomal biomarkers of acute T cell-mediated rejection in kidney transplant recipients: a cross-sectional study. PLoS ONE. 2018;13: e0204204. https://doi.org/10.1371/journal.pone.0204204.
Article CAS PubMed PubMed Central Google Scholar
Tower CM, Reyes M, Nelson K, Leca N, Kieran N, Muczynski K, et al. Plasma C4d+ endothelial microvesicles increase in acute antibody-mediated rejection. Transplantation. 2017;101:2235–43. https://doi.org/10.1097/TP.0000000000001572.
Article CAS PubMed Google Scholar
Zhang H, Huang E, Kahwaji J, Nast CC, Li P, Mirocha J, et al. Plasma exosomes from HLA-sensitized kidney transplant recipients contain mRNA transcripts which predict development of antibody-mediated rejection. Transplantation. 2017;101:2419–28. https://doi.org/10.1097/TP.0000000000001834.
Article CAS PubMed Google Scholar
Woud WW, Hesselink DA, Hoogduijn MJ, Baan CC, Boer K. Direct detection of circulating donor-derived extracellular vesicles in kidney transplant recipients. Sci Rep. 2022;12:21973. https://doi.org/10.1038/s41598-022-26580-6.
Article CAS PubMed PubMed Central Google Scholar
Gunasekaran M, Xu Z, Nayak D, Sharma M, Hachem R, Walia R, et al. Donor-derived exosomes with lung self-antigens in human lung allograft rejection. Am J Transplant. 2017;17:474–84. https://doi.org/10.1111/ajt.13915.
Article CAS PubMed Google Scholar
Wojciechowski D, Wiseman A. Long-term immunosuppression management. Clin J Am Soc Nephrol. 2021;16:1264–71. https://doi.org/10.2215/CJN.15040920.
Article CAS PubMed PubMed Central Google Scholar
van Niel G, D’Angelo G, Raposo G. Shedding light on the cell biology of extracellular vesicles. Nat Rev Mol Cell Biol. 2018;19:213–28. https://doi.org/10.1038/nrm.2017.125.
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