Anger HO. Scintillation camera. Rev Sci Instrum. 1958;29:27–33.
Cassen B, Curtis L, Reed C, Libby R. Instrumentation for I-131 use in medical studies. Nucleonics. 1951;9:46–50.
Tollefson J. Reactor shutdown threatens world’s medical-isotope supply. Nature. 2016;12.
Rivard MJ, Bobek LM, Butler RA, Garland MA, Hill DJ, Krieger JK, et al. The US national isotope program: current status and strategy for future success. Appl Radiat Isot. 2005;63:157–78.
Sasaki Y. Nuclear oncology as seen by me in Japan: a historical review and future perspective. Ann Nucl Med. 2020;34:1–12.
Baidoo KE, Yong K, Brechbiel MW. Molecular pathways: targeted α-particle radiation therapy. Clin Cancer Res. 2013;19:530–7.
Poty S, Francesconi LC, McDevitt MR, Morris MJ, Lewis JS. α-emitters for radiotherapy: from basic radiochemistry to clinical studies—part 2. J Nucl Med. 2018;59:1020–7.
CAS PubMed PubMed Central Google Scholar
Scheinberg A. R McDevitt M. Actinium-225 in targeted alpha-particle therapeutic applications. Curr Radiopharm. 2011;4:306–20.
CAS PubMed PubMed Central Google Scholar
McDevitt MR, Finn RD, Ma D, Larson SM, Scheinberg DA. Preparation of α-emitting 213Bi-labeled antibody constructs for clinical use. J Nucl Med. 1999;40:1722–7.
Nilsson S, Larsen RH, Fosså SD, Balteskard L, Borch KW, Westlin J-E, et al. First clinical experience with α-emitting radium-223 in the treatment of skeletal metastases. Clin Cancer Res. 2005;11:4451–9.
García-Toraño E, Medina VP, Romero E, Roteta M. Measurement of the half-life of 68Ga. Appl Radiat Isot. 2014;87:122–5.
Lepareur N. Cold kit labeling: the future of 68Ga radiopharmaceuticals? Front Med. 2022;9:812050.
Mettler F, Guiberteau M. Radioactivity, radionuclides, and radiopharmaceuticals. Essentials of nuclear medicine and molecular imaging. Philadelphia: Elsevier; 2019.
Forgacs P. The gallium scan and inflammatory lesions. Arch Intern Med. 1982;142:231.
Zuckier LS, Valdivia AY, Zamora E. Does gallium-citrate have yet another story to tell? Lessons relevant to the COVID-19 era. Eur J Nucl Med Mol Imaging. 2020;47:2059–61.
CAS PubMed PubMed Central Google Scholar
George K, Borjian S, Cross M, Hicks J, Schaffer P, Kovacs M. Expanding the PET radioisotope universe utilizing solid targets on small medical cyclotrons. RSC Adv. 2021;11:31098–123.
CAS PubMed PubMed Central Google Scholar
Rinne SS, Abouzayed A, Gagnon K, Tolmachev V, Orlova A. 66Ga-PET-imaging of GRPR-expression in prostate caproductionuction and characterization of [66Ga] Ga-NOTA-PEG2-RM26. Sci Rep. 2021;11:3631.
CAS PubMed PubMed Central Google Scholar
Kossert K, Schrader H. Activity standardization by liquid scintillation counting and half-life measurements of 90Y. Appl Radiat Isot. 2004;60:741–9.
Yoo J, Tang L, Perkins TA, Rowland DJ, Laforest R, Lewis JS, et al. Preparation of high specific activity 86Y using a small biomedical cyclotron. Nucl Med Biol. 2005;32:891–7.
Braad P, Hansen S, Thisgaard H, Høilund-Carlsen P. PET imaging with the non-pure positron emitters: 55Co, 86Y and 124I. Phys Med Biol. 2015;60:3479.
Dash A, Pillai MRA, Knapp FF. Production of 177Lu for targeted radionuclide therapy: available options. Nucl Med Mol Imaging (2010). 2015;49:85–107.
de Aguiar Ferreira C, Fuscaldi LL, Townsend DM, Rubello D, de Barros ALB. Radiolabeled bombesin derivatives for preclinical oncological imaging. Biomed Pharmacother. 2017;87:58–72.
Hong JH. An update of prostate-specific membrane antigen theranostics in prostate cancer. Korean J Urol Oncol. 2022;20:207–22.
Pommé S, Marouli M, Suliman G, Dikmen H, Van Ammel R, Jobbágy V, et al. Measurement of the 225Ac half-life. Appl Radiat Isot. 2012;70:2608–14.
Hassan M, Bokhari TH, Lodhi NA, Khosa MK, Usman M. A review of recent advancements in Actinium-225 labeled compounds and biomolecules for therapeutic purposes. Chem Biol Drug Des. 2023;102:1276–92.
Rahman AR, Babu MH, Ovi MK, Zilani MM, Eithu IS, Chakraborty A. Actinium-225 in targeted alpha therapy. J Med Phys. 2024;49:137–47.
PubMed PubMed Central Google Scholar
Jurisson SS, Lydon JD. Potential technetium small molecule radiopharmaceuticals. Chem Rev. 1999;99:2205–18.
Green CH. Technetium-99m production issues in the United Kingdom. J Med Phys. 2012;37:66–71.
PubMed PubMed Central Google Scholar
Wenzl M, Colombo F, Guanais F, Lopert R, Paris V, Pearson M, et al. The supply of Medical isotopes: an economic diagnosis and possible solutions. OECD; 2019.
Lederer CM, Hollander JM, Perlman I, Segrè EG. Table of isotopes. Phys Today. 1967;20:97–9.
Parker C, Heidenreich A, Nilsson S, Shore N. Current approaches to incorporation of radium-223 in clinical practice. Prostate Cancer Prostatic Dis. 2018;21:37–47.
CAS PubMed PubMed Central Google Scholar
Abou DS, Ulmert D, Doucet M, Hobbs RF, Riddle RC, Thorek DL. Whole-body and microenvironmental localization of radium-223 in naive and mouse models of prostate cancer metastasis. J Natl Cancer Inst. 2016;108:djv380.
Basch E, Loblaw DA, Oliver TK, Carducci M, Chen RC, Frame JN, et al. Systemic therapy in men with metastatic castration-resistant prostate cancer: American Society of Clinical Oncology and Cancer Care Ontario clinical practice guideline. J Clin Oncol. 2014;32:3436–48.
CAS PubMed PubMed Central Google Scholar
Ahenkorah S, Cassells I, Deroose CM, Cardinaels T, Burgoyne AR, Bormans G, et al. Bismuth-213 for targeted radionuclide therapy: from atom to bedside. Pharmaceutics. 2021;13:599.
CAS PubMed PubMed Central Google Scholar
Franchi S, Di Marco V, Tosato M. Bismuth chelation for targeted alpha therapy: current state of the art. Nucl Med Biol. 2022;114:168–88.
Knapp FF, Dash A. Radiopharmaceuticals for therapy. Springer; 2016.
Jurcic JG, Larson SM, Sgouros G, McDevitt MR, Finn RD, Divgi CR, et al. Targeted α particle immunotherapy for myeloid leukemia. Blood. 2002;100:1233–9.
Allen BJ, Raja C, Rizvi S, Li Y, Tsui W, Graham P, et al. Intralesional targeted alpha therapy for metastatic melanoma. Cancer Biol Ther. 2005;4:1318–24.
Chan HS, De Blois E, Morgenstern A, Bruchertseifer F, De Jong M, Breeman W, et al. In Vitro comparison of 213Bi-and 177Lu-radiation for peptide receptor radionuclide therapy. PLoS ONE. 2017;12:e0181473.
PubMed PubMed Central Google Scholar
Gustafsson-Lutz A, Bäck T, Aneheim E, Hultborn R, Palm S, Jacobsson L, et al. Therapeutic efficacy of α-radioimmunotherapy with different activity levels of the 213Bi-labeled monoclonal antibody MX35 in an ovarian cancer model. EJNMMI Res. 2017;7:1–8.
Fichou N, Gouard S, Maurel C, Barbet J, Ferrer L, Morgenstern A, et al. Single-dose anti-CD138 radioimmunotherapy: bismuth-213 is more efficient than lutetium-177 for treatment of multiple myeloma in a preclinical model. Front Med. 2015;2:76.
Królicki L, Bruchertseifer F, Kunikowska J, Koziara H, Królicki B, Jakuciński M, et al. Safety and efficacy of targeted alpha therapy with 213Bi-DOTA-substance P in recurrent glioblastoma. Eur J Nucl Med Mol Imaging. 2019;46:614–22.
Holland JP, Ferdani R, Anderson CJ, Lewis JS. Copper-64 radiopharmaceuticals for oncologic imaging. PET Clin. 2009;4:49–67.
PubMed PubMed Central Google Scholar
Nedrow JR, White AG, Modi J, Nguyen K, Chang AJ, Anderson CJ. Positron emission tomographic imaging of copper 64–and gallium 68–labeled chelator conjugates of the somatostatin agonist Tyr3-octreotate. Mol Imaging. 2014;13:1–13.
Braune A, Oehme L, Freudenberg R, Hofheinz F, van den Hoff J, Kotzerke J, et al. Comparison of image quality and spatial resolution between 18F, 68Ga, and 64Cu phantom measurements using a digital Biograph Vision PET/CT. EJNMMI Phys. 2022;9:58.
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