Inflammatory and lipemic response to red meat intake in women with and without Rheumatoid Arthritis: a single meal study within a randomized controlled trial

Smolen JS, Aletaha D, McInnes IB. Rheumatoid arthritis. Lancet. 2016;388(10055):2023. https://doi.org/10.1016/S0140-6736(16)30173-8.

Article  PubMed  CAS  Google Scholar 

Black RJ, Cross M, Haile LM, Culbreth GT, Steinmetz JD, Hagins H, et al. Global, regional, and national burden of rheumatoid arthritis, 1990–2020, and projections to 2050: a systematic analysis of the Global Burden of Disease Study 2021. Lancet Rheumatol. 2023;5(10):e594–610. https://doi.org/10.1016/S2665-9913(23)00211-4.

Article  Google Scholar 

Matcham F, Scott IC, Rayner L, Hotopf M, Kingsley GH, Norton S, et al. The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: a systematic review and meta-analysis. Semin Arthritis Rheum. 2014;44(2):123–30. https://doi.org/10.1016/j.semarthrit.2014.05.001.

Article  PubMed  Google Scholar 

Avina-Zubieta JA, Thomas J, Sadatsafavi M, Lehman AJ, Lacaille D. Risk of incident cardiovascular events in patients with rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis. 2012;71(9):1524–9. https://doi.org/10.1136/annrheumdis-2011-200726.

Article  PubMed  Google Scholar 

England BR, Thiele GM, Anderson DR, Mikuls TR. Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications. BMJ. 2018;361:k1036-k. https://doi.org/10.1136/bmj.k1036.

Article  PubMed  PubMed Central  Google Scholar 

Borén J, Chapman MJ, Krauss RM, Packard CJ, Bentzon JF, Binder CJ, et al. Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2020;41(24):2313–30. https://doi.org/10.1093/eurheartj/ehz962.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Ginsberg HN, Packard CJ, Chapman MJ, Borén J, Aguilar-Salinas CA, Averna M, et al. Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society. Eur Heart J. 2021;42(47):4791–806. https://doi.org/10.1093/eurheartj/ehab551.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Nordestgaard BG, Langsted A, Mora S, Kolovou G, Baum H, Bruckert E, et al. Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine. Eur Heart J. 2016;37(25):1944–58. https://doi.org/10.1093/eurheartj/ehw152.

Article  PubMed  PubMed Central  Google Scholar 

Van Oostrom AJ, Castro Cabezas M, Ribalta J, Masana L, Twickler TB, Remijnse TA, et al. Diurnal triglyceride profiles in healthy normolipidemic male subjects are associated to insulin sensitivity, body composition and diet. Eur J Clin Invest. 2000;30(11):964–71. https://doi.org/10.1046/j.1365-2362.2000.00732.x.

Article  PubMed  Google Scholar 

Keirns BH, Sciarrillo CM, Poindexter KL, Emerson SR. Daily Triglyceride Kinetics When Consuming a Realistic Western Diet in at-Risk Individuals across the Metabolic Spectrum: A Case Study. Obesities. 2021;1(2):107–12. https://doi.org/10.3390/obesities1020010.

Article  Google Scholar 

Borén J, Matikainen N, Adiels M, Taskinen M-R. Postprandial hypertriglyceridemia as a coronary risk factor. Clin Chim Acta. 2014;431:131–42. https://doi.org/10.1016/j.cca.2014.01.015.

Article  PubMed  CAS  Google Scholar 

Nakamura K, Miyoshi T, Yunoki K, Ito H. Postprandial hyperlipidemia as a potential residual risk factor. J Cardiol. 2016;67(4):335–9. https://doi.org/10.1016/j.jjcc.2015.12.001.

Article  PubMed  Google Scholar 

Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, et al. Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013;65(12):2046–50. https://doi.org/10.1002/acr.22091.

Article  PubMed  CAS  Google Scholar 

Tang MW, Koopman FA, Visscher JPM, de Hair MJ, Gerlag DM, Tak PP. Hormone, metabolic peptide, and nutrient levels in the earliest phases of rheumatoid arthritis—contribution of free fatty acids to an increased cardiovascular risk during very early disease. Clin Rheumatol. 2017;36(2):269–78. https://doi.org/10.1007/s10067-016-3456-x.

Myasoedova E, Crowson CS, Kremers HM, Fitz-Gibbon PD, Therneau TM, Gabriel SE. Total cholesterol and LDL levels decrease before rheumatoid arthritis. Ann Rheum Dis. 2010;69(7):1310–4. https://doi.org/10.1136/ard.2009.122374.

Article  PubMed  CAS  Google Scholar 

McGrath CM, Young SP. Lipid and Metabolic Changes in Rheumatoid Arthritis. Curr Rheumatol Rep. 2015;17(9):57. https://doi.org/10.1007/s11926-015-0534-z.

Article  PubMed  CAS  Google Scholar 

Mena-Vázquez N, Rojas-Gimenez M, Jimenez Nuñez FG, Manrique-Arija S, Rioja J, Ruiz-Limón P, et al. Postprandial Apolipoprotein B48 is Associated with Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis. J Clin Med. 2020;9(8):2483. https://doi.org/10.3390/jcm9082483.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Herieka M, Erridge C. High-fat meal induced postprandial inflammation. Mol Nutr Food Res. 2014;58(1):136–46. https://doi.org/10.1002/mnfr.201300104.

Article  PubMed  CAS  Google Scholar 

Meessen ECE, Warmbrunn MV, Nieuwdorp M, Soeters MR. Human postprandial nutrient metabolism and low-grade inflammation: A narrative review. Nutrients. 2019;11(12):3000. https://doi.org/10.3390/nu11123000.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005;352(16):1685–95. https://doi.org/10.1056/NEJMra043430.

Article  PubMed  CAS  Google Scholar 

Emerson SR, Kurti SP, Harms CA, Haub MD, Melgarejo T, Logan C, et al. Magnitude and Timing of the Postprandial Inflammatory Response to a High-Fat Meal in Healthy Adults: A Systematic Review. Adv Nutr. 2017;8(2):213–25. https://doi.org/10.3945/an.116.014431.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Salminen E, Heikkila S, Poussa T, Lagstrom H, Saario R, Salminen S. Female patients tend to alter their diet following the diagnosis of rheumatoid arthritis and breast cancer. Prev Med. 2002;34(5):529–35. https://doi.org/10.1006/pmed.2002.1015.

Article  PubMed  Google Scholar 

Tedeschi SK, Frits M, Cui J, Zhang ZZ, Mahmoud T, Iannaccone C, et al. Diet and Rheumatoid Arthritis Symptoms: Survey Results From a Rheumatoid Arthritis Registry. Arthritis Care Res (Hoboken). 2017;69(12):1920–5. https://doi.org/10.1002/acr.23225.

Article  PubMed  CAS  Google Scholar 

Meinilä J, Virtanen JK. Meat and meat products - a scoping review for Nordic Nutrition Recommendations 2023. Food Nutr Res. 2024;68. https://doi.org/10.29219/fnr.v68.10538.

Ley SH, Sun Q, Willett WC, Eliassen AH, Wu K, Pan A, et al. Associations between red meat intake and biomarkers of inflammation and glucose metabolism in women. Am J Clin Nutr. 2014;99(2):352–60. https://doi.org/10.3945/ajcn.113.075663.

Article  PubMed  CAS  Google Scholar 

Papier K, Hartman L, Tong TYN, Key TJ, Knuppel A. Higher Meat Intake Is Associated with Higher Inflammatory Markers, Mostly Due to Adiposity: Results from UK Biobank. J Nutr. 2022;152(1):183–9. https://doi.org/10.1093/jn/nxab314.

Article  PubMed  Google Scholar 

Zhang B, Pu L, Zhao T, Wang L, Shu C, Xu S, et al. Global Burden of Cardiovascular Disease from 1990 to 2019 Attributable to Dietary Factors. J Nutr. 2023;153(6):1730–41. https://doi.org/10.1016/j.tjnut.2023.03.031.

Article  PubMed  Google Scholar 

Guasch-Ferré M, Satija A, Blondin SA, Janiszewski M, Emlen E, O’Connor LE, et al. Meta-Analysis of Randomized Controlled Trials of Red Meat Consumption in Comparison With Various Comparison Diets on Cardiovascular Risk Factors. Circulation. 2019;139(15):1828–45. https://doi.org/10.1161/circulationaha.118.035225.

Article  PubMed  Google Scholar 

Hulander E, Bärebring L, Winkvist A, Gjertsson I, Lindqvist HM. A randomized controlled cross-over trial investigating the acute inflammatory and metabolic response after meals based on red meat, fatty fish, or soy protein: the postprandial inflammation in rheumatoid arthritis (PIRA) trial. Eur J Nutr. 2024. https://doi.org/10.1007/s00394-024-03451-6.

Article  PubMed  PubMed Central 

Comments (0)

No login
gif