Freeman R. Autonomic Peripheral Neuropathy. Contin Lifelong Learn Neurol. 2020;26(1):58. https://doi.org/10.1212/CON.0000000000000825.
Mendoza-Velásquez JJ, Flores-Vázquez JF, Barrón-Velázquez E, Sosa-Ortiz AL, Illigens B-MW, Siepmann T. Autonomic Dysfunction in α-Synucleinopathies. Front Neurol. 2019;10:363. https://doi.org/10.3389/fneur.2019.00363.
Article PubMed PubMed Central Google Scholar
Fedorowski A, et al. Orthostatic Hypotension: Management of a Complex, But Common, Medical Problem. Circ Arrhythm Electrophysiol. 2022;15(3): e010573. https://doi.org/10.1161/CIRCEP.121.010573.
Article PubMed PubMed Central Google Scholar
Freeman R, et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin Auton Res Off J Clin Auton Res Soc. 2011;21(2):69–72. https://doi.org/10.1007/s10286-011-0119-5.
Juraschek SP, et al. Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults. JAMA Intern Med. 2017;177(9):1316–23. https://doi.org/10.1001/jamainternmed.2017.2937.
Article PubMed PubMed Central Google Scholar
Raj SR, et al. Sodium paradoxically reduces the gastropressor response in patients with orthostatic hypotension. Hypertens. 2006;48(2):329–34. https://doi.org/10.1161/01.HYP.0000229906.27330.4f.
Z’Graggen WJ, Hess CW, Humm AM. Acute fluid ingestion in the treatment of orthostatic intolerance - important implications for daily practice. Eur J Neurol. 2010;17(11):1370–6. https://doi.org/10.1111/j.1468-1331.2010.03030.x.
Eschlböck S, Wenning G, and Fanciulli A “Correction to: Evidence-based treatment of neurogenic orthostatic hypotension and related symptoms,” J. Neural Transm. Vienna Austria 1996 2018;125(2): 273–274 https://doi.org/10.1007/s00702-017-1814-8.
Tutaj M, Marthol H, Berlin D, Brown CM, Axelrod FB, Hilz MJ. Effect of physical countermaneuvers on orthostatic hypotension in familial dysautonomia. J Neurol. 2006;253(1):65–72. https://doi.org/10.1007/s00415-005-0928-3.
Smit AAJ, et al. Use of lower abdominal compression to combat orthostatic hypotension in patients with autonomic dysfunction. Clin Auton Res Off J Clin Auton Res Soc. 2004;14(3):167–75. https://doi.org/10.1007/s10286-004-0187-x.
Fanciulli A, et al. Elastic Abdominal Binders Attenuate Orthostatic Hypotension in Parkinson’s Disease. Mov Disord Clin Pract. 2016;3(2):156–60. https://doi.org/10.1002/mdc3.12270.
Shibata S, Fu Q, Bivens TB, Hastings JL, Wang W, Levine BD. Short-term exercise training improves the cardiovascular response to exercise in the postural orthostatic tachycardia syndrome. J Physiol. 2012;590(15):3495–505. https://doi.org/10.1113/jphysiol.2012.233858.
Article PubMed PubMed Central CAS Google Scholar
Gonçalves Leite Rocco P, Reategui-Rivera CM, and Finkelstein J “Exercise Interventions in the Management of Postural Orthostatic Tachycardia Syndrome: A Scoping Review,” J. Multidiscip. Healthc 2024;17: 5867–5885 https://doi.org/10.2147/JMDH.S495088.
Liu H, et al. Effectiveness and safety of acupuncture combined with Madopar for Parkinson’s disease: a systematic review with meta-analysis. Acupunct Med J Br Med Acupunct Soc. 2017;35(6):404–12. https://doi.org/10.1136/acupmed-2016-011342.
Freeman R. Treatment of orthostatic hypotension. Semin Neurol. 2003;23(4):435–42. https://doi.org/10.1055/s-2004-817727.
Oelkers W, Buchen S, Diederich S, Krain J, Muhme S, Schöneshöfer M. Impaired renal 11 beta-oxidation of 9 alpha-fluorocortisol: an explanation for its mineralocorticoid potency. J Clin Endocrinol Metab. 1994;78(4):928–32. https://doi.org/10.1210/jcem.78.4.8157723.
Article PubMed CAS Google Scholar
“A highly sensitive method for the quantification of fludrocortisone in human plasma using ultra-high-performance liquid chromatography tandem mass spectrometry and its pharmacokinetic application - PubMed.” Accessed: Dec. 16, 2024.[Online]. Available: https://pubmed.ncbi.nlm.nih.gov/25611194/
Hamitouche N, Comets E, Ribot M, Alvarez J-C, Bellissant E, Laviolle B. Population Pharmacokinetic-Pharmacodynamic Model of Oral Fludrocortisone and Intravenous Hydrocortisone in Healthy Volunteers. AAPS J. 2017;19(3):727–35. https://doi.org/10.1208/s12248-016-0041-9.
Article PubMed CAS Google Scholar
Davies IB, Bannister RG, Sever PS, Wilcox CS. Fludrocortisone in the treatment of postural hypotension: altered sensitivity to pressor agents[proceedings]. Br J Clin Pharmacol. 1978;6(5):444P-445P.
Article PubMed CAS Google Scholar
Chobanian AV, Volicer L, Tifft CP, Gavras H, Liang CS, Faxon D. Mineralocorticoid-induced hypertension in patients with orthostatic hypotension. N Engl J Med. 1979;301(2):68–73. https://doi.org/10.1056/NEJM197907123010202.
Article PubMed CAS Google Scholar
van Lieshout JJ, ten Harkel AD, Wieling W. Fludrocortisone and sleeping in the head-up position limit the postural decrease in cardiac output in autonomic failure. Clin Auton Res Off J Clin Auton Res Soc. 2000;10(1):35–42. https://doi.org/10.1007/BF02291388.
Distler A, et al. Sympathetic tone and pressor response to noradrenaline during mineralocorticoid-induced blood pressure rise in man. J Hypertens Suppl Off J Int Soc Hypertens. 1985;3(4):S27-32.
Jankovic J, Hallett M, Okun MS, Comella C, Fahn S, and Goldman J “Chapter 9 - Atypical parkinsonism, parkinsonism-plus syndromes and secondary parkinsonian disorders,” In Principles and Practice of Movement Disorders (Third Edition), J. Jankovic, M. Hallett, M. S. Okun, C. Comella, S. Fahn, and J. Goldman, Eds., London: Elsevier, 2021, pp. 249–295.e17. https://doi.org/10.1016/B978-0-323-31071-0.00009-3.
“Fludrocortisone.” Accessed: Dec. 16, 2024.[Online]. Available: https://go.drugbank.com/drugs/DB00687
Smith W, Wan H, Much D, Robinson AG, Martin P. Clinical benefit of midodrine hydrochloride in symptomatic orthostatic hypotension: a phase 4, double-blind, placebo-controlled, randomized, tilt-table study. Clin Auton Res Off J Clin Auton Res Soc. 2016;26(4):269–77. https://doi.org/10.1007/s10286-016-0363-9.
Byun J-I, et al. Efficacy of single or combined midodrine and pyridostigmine in orthostatic hypotension. Neurology. 2017;89(10):1078–86. https://doi.org/10.1212/WNL.0000000000004340.
Article PubMed CAS Google Scholar
Byun J-I, et al. Efficacy of atomoxetine versus midodrine for neurogenic orthostatic hypotension. Ann Clin Transl Neurol. 2020;7(1):112–20. https://doi.org/10.1002/acn3.50968.
Article PubMed CAS Google Scholar
“Midodrine.” Accessed: Dec. 16, 2024.[Online]. Available: https://go.drugbank.com/drugs/DB00211
Mathias CJ. L-dihydroxyphenylserine (Droxidopa) in the treatment of orthostatic hypotension. Clin Auton Res. 2008;18(1):25–9. https://doi.org/10.1007/s10286-007-1005-z.
“Drugs@FDA: FDA-Approved Drugs; NORTHERA® (droxidopa).” Accessed: Dec. 21, 2024.[Online]. Available: https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=203202
Goldstein DS. L-Dihydroxyphenylserine (L-DOPS): A Norepinephrine Prodrug. Cardiovasc Drug Rev. 2006;24(3–4):189–203. https://doi.org/10.1111/j.1527-3466.2006.00189.x.
Article PubMed CAS Google Scholar
Chen JJ, Hewitt LA. Comparison of the Pharmacokinetics of Droxidopa After Dosing in the Fed Versus Fasted State and with 3-Times-Daily Dosing in Healthy Elderly Subjects. Drugs RD. 2018;18(1):77–86. https://doi.org/10.1007/s40268-018-0226-z.
Isaacson S, Shill HA, Vernino S, Ziemann A, Rowse GJ. Safety and Durability of Effect with Long-Term, Open-Label Droxidopa Treatment in Patients with Symptomatic Neurogenic Orthostatic Hypotension (NOH303). J Park Dis. 2016;6(4):751–9. https://doi.org/10.3233/JPD-160860.
Biaggioni I, Arthur Hewitt L, Rowse GJ. and Kaufmann H “Integrated analysis of droxidopa trials for neurogenic orthostatic hypotension.” BMC Neurol. 2017;17(1):90. https://doi.org/10.1186/s12883-017-0867-5.
Article PubMed PubMed Central Google Scholar
Hauser RA, Isaacson S, Lisk JP, Hewitt LA, Rowse G. Droxidopa for the Short-Term Treatment of Symptomatic Neurogenic Orthostatic Hypotension in Parkinson’s Disease (nOH306B). Mov Disord. 2015;30(5):646–54. https://doi.org/10.1002/mds.26086.
Article PubMed CAS Google Scholar
Kaufmann H, et al. Droxidopa for neurogenic orthostatic hypotension. Neurology. 2014;83(4):328–35. https://doi.org/10.1212/WNL.0000000000000615.
Comments (0)