Mecoli, C. A., Rosen, A., Casciola-Rosen, L. & Shah, A. A. Advances at the interface of cancer and systemic sclerosis. J. Scleroderma Relat. Disord. 6, 50–57 (2021).
Artlett, C. M., Black, C. M., Briggs, D. C., Stephens, C. & Welsh, K. I. DNA allelic alterations within VNTR loci of scleroderma families. Br. J. Rheumatol. 35, 1216–1222 (1996).
Article CAS PubMed Google Scholar
Artlett, C. M., Black, C. M., Briggs, D. C., Stevens, C. O. & Welsh, K. I. Telomere reduction in scleroderma patients: a possible cause for chromosomal instability. Br. J. Rheumatol. 35, 732–737 (1996).
Article CAS PubMed Google Scholar
Vijayraghavan, S. et al. Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis. Nat. Commun. 15, 8889 (2024).
Article CAS PubMed PubMed Central Google Scholar
Torreggiani, S., Castellan, F. S., Aksentijevich, I. & Beck, D. B. Somatic mutations in autoinflammatory and autoimmune disease. Nat. Rev. Rheumatol. 20, 683–698 (2024).
Nonaka, T. et al. Involvement of activation-induced cytidine deaminase in skin cancer development. J. Clin. Invest. 126, 1367–1382 (2016).
Article PubMed PubMed Central Google Scholar
Paul, S. et al. Centromere defects, chromosome instability, and cGAS-STING activation in systemic sclerosis. Nat. Commun. 13, 7074 (2022).
Article CAS PubMed PubMed Central Google Scholar
Artlett, C. M. et al. The inflammasome activating caspase-1 mediates fibrosis and myofibroblast differentiation in systemic sclerosis. Arthritis Rheum. 63, 3563–3574 (2011).
Article CAS PubMed Google Scholar
Wyman, A. E. & Atamas, S. P. Sirtuins and accelerated aging in scleroderma. Curr. Rheumatol. Rep. 20, 16 (2018).
Article PubMed PubMed Central Google Scholar
Yun, J. H. et al. Clonal somatic mutations in chronic lung diseases are associated with reduced lung function. Am. J. Respir. Crit. Care Med. 208, 1196–1205 (2023).
Comments (0)