Coeliac disease: complications and comorbidities

Lebwohl, B., Sanders, D. S. & Green, P. H. R. Coeliac disease. Lancet 391, 70–81 (2018).

Article  PubMed  Google Scholar 

Ludvigsson, J. F. et al. The Oslo definitions for coeliac disease and related terms. Gut 62, 43–52 (2013).

Article  PubMed  Google Scholar 

Al-Toma, A. et al. European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders. U Eur. Gastroenterol. J. 7, 583–613 (2019).

Article  Google Scholar 

Rubio-Tapia, A., Hill, I. D., Semrad, C., Kelly, C. P. & Lebwohl, B. American College of Gastroenterology guidelines update: diagnosis and management of celiac disease. Am. J. Gastroenterol. 118, 59–76 (2023).

Article  PubMed  CAS  Google Scholar 

Lebwohl, B., Green, P. H. R., Söderling, J., Roelstraete, B. & Ludvigsson, J. F. Association between celiac disease and mortality risk in a Swedish population. JAMA 323, 1277–1285 (2020).

Article  PubMed  PubMed Central  Google Scholar 

Elfström, P., Sundström, J. & Ludvigsson, J. F. Systematic review with meta-analysis: associations between coeliac disease and type 1 diabetes. Aliment. Pharmacol. Ther. 40, 1123–1132 (2014).

Article  PubMed  Google Scholar 

Elfstrom, P., Montgomery, S. M., Kampe, O., Ekbom, A. & Ludvigsson, J. F. Risk of thyroid disease in individuals with celiac disease. J. Clin. Endocrinol. Metab. 93, 3915–3921 (2008).

Article  PubMed  Google Scholar 

Wang, Q., Jia, S., Lu, Q. & Zhao, M. Systemic lupus erythematosus is associated with the risk of coeliac disease: a Mendelian randomisation study. Autoimmunity 56, 2250103 (2023).

Article  PubMed  Google Scholar 

Haggård, L. et al. High prevalence of celiac disease in autoimmune hepatitis: systematic review and meta-analysis. Liver Int. 41, 2693–2702 (2021).

Article  PubMed  Google Scholar 

Ludvigsson, J. F., Rubio-Tapia, A., Chowdhary, V., Murray, J. A. & Simard, J. F. Increased risk of systemic lupus erythematosus in 29,000 patients with biopsy-verified celiac disease. J. Rheumatol. 39, 1964–1970 (2012).

Article  PubMed  PubMed Central  Google Scholar 

Emilsson, L., Semrad, C., Lebwohl, B., Green, P. H. R. & Ludvigsson, J. F. Risk of small bowel adenocarcinoma, adenomas, and carcinoids in a nationwide cohort of individuals with celiac disease. Gastroenterology 159, 1686–1694 (2020).

Article  PubMed  Google Scholar 

Elfström, P. et al. Risk of lymphoproliferative malignancy in relation to small intestinal histopathology among patients with celiac disease. J. Natl Cancer Inst. 103, 436–444 (2011).

Article  PubMed  Google Scholar 

Lebwohl, B. et al. Psychiatric disorders in patients with a diagnosis of celiac disease during childhood from 1973 to 2016. Clin. Gastroenterol. Hepatol. 19, 2093–2101 (2021).

Article  PubMed  Google Scholar 

Abdul Sultan, A. et al. Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England. Am. J. Gastroenterol. 109, 1653–1661 (2014).

Article  PubMed  Google Scholar 

Marild, K. et al. Costs and use of health care in patients with celiac disease: a population-based longitudinal study. Am. J. Gastroenterol. 115, 1253–1263 (2020).

Article  PubMed  Google Scholar 

Bozorg, S. R. et al. Work loss in patients with celiac disease: a population-based longitudinal study. Clin. Gastroenterol. Hepatol. 20, 1068–1076 (2022).

Article  PubMed  CAS  Google Scholar 

Singh, P. et al. Global prevalence of celiac disease: systematic review and meta-analysis. Clin. Gastroenterol. Hepatol. 16, 823–836 (2018).

Article  PubMed  Google Scholar 

King, J. A. et al. Incidence of celiac disease is increasing over time: a systematic review and meta-analysis. Am. J. Gastroenterol. 115, 507–525 (2020).

Article  PubMed  Google Scholar 

Bergman, D. et al. Two waves of coeliac disease incidence in Sweden: a nationwide population-based cohort study from 1990 to 2015. Gut 71, 1088–1094 (2022).

Article  PubMed  Google Scholar 

Ludvigsson, J. F. et al. Increasing incidence of celiac disease in a North American population. Am. J. Gastroenterol. 108, 818–824 (2013).

Article  PubMed  PubMed Central  Google Scholar 

Godfrey, J. D. et al. Morbidity and mortality among older individuals with undiagnosed celiac disease. Gastroenterology 139, 763–769 (2010).

Article  PubMed  Google Scholar 

Sevilla, W. M. A. Nutritional considerations in pediatric chronic disease. Pediatr. Rev. 38, 343–352 (2017).

Article  PubMed  Google Scholar 

Tapsas, D., Hollen, E., Stenhammar, L. & Falth-Magnusson, K. The clinical presentation of coeliac disease in 1030 Swedish children: changing features over the past four decades. Dig. Liver Dis. 48, 16–22 (2016).

Article  PubMed  Google Scholar 

Maki, M., Kallonen, K., Lahdeaho, M. L. & Visakorpi, J. K. Changing pattern of childhood coeliac disease in Finland. Acta Paediatr. Scand. 77, 408–412 (1988).

Article  PubMed  CAS  Google Scholar 

Ascher, H., Holm, K., Kristiansson, B. & Maki, M. Different features of coeliac disease in two neighbouring countries. Arch. Dis. Child. 69, 375–380 (1993).

Article  PubMed  CAS  PubMed Central  Google Scholar 

Thomas, E. T. et al. Trends in diagnostic tests ordered for children: a retrospective analysis of 1.7 million laboratory test requests in Oxfordshire, UK from 2005 to 2019. Arch. Dis. Child. 109, 30–36 (2023).

Article  PubMed  Google Scholar 

King, J. A. et al. Variation in testing for and incidence of celiac autoimmunity in Canada: a population-based study. Gastroenterology 164, 567–578 (2023).

Article  PubMed  CAS  Google Scholar 

Olen, O., Montgomery, S. M., Marcus, C., Ekbom, A. & Ludvigsson, J. F. Coeliac disease and body mass index: a study of two Swedish general population-based registers. Scand. J. Gastroenterol. 44, 1198–1206 (2009).

Article  PubMed  Google Scholar 

Sonti, R. et al. Men with celiac disease are shorter than their peers in the general population. Eur. J. Gastroenterol. Hepatol. 25, 1033–1037 (2013).

Article  PubMed  Google Scholar 

Lebwohl, B. et al. Long term gluten consumption in adults without celiac disease and risk of coronary heart disease: prospective cohort study. BMJ 357, j1892 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Ogborn, A. D. Pregnancy in patients with coeliac disease. Br. J. Obstet. Gynaecol. 82, 293–296 (1975).

Article  PubMed  CAS  Google Scholar 

Meloni, G. F., Dessole, S., Vargiu, N., Tomasi, P. A. & Musumeci, S. The prevalence of coeliac disease in infertility. Hum. Reprod. 14, 2759–2761 (1999).

Article  PubMed  CAS  Google Scholar 

Tata, L. J. et al. Fertility and pregnancy-related events in women with celiac disease: a population-based cohort study. Gastroenterology 128, 849–855 (2005).

Article  PubMed  CAS  Google Scholar 

Dhalwani, N. N., West, J., Sultan, A. A., Ban, L. & Tata, L. J. Women with celiac disease present with fertility problems no more often than women in the general population. Gastroenterology 147, 1267–1274 (2014).

Article  PubMed  Google Scholar 

Grode, L. et al. Reproductive life in women with celiac disease; a nationwide, population-based matched cohort study. Hum. Reprod. 33, 1538–1547 (2018).

Article 

Comments (0)

No login
gif