Metabolome analysis in patients with heart failure and implantable cardioverter defibrillators

Ikegami R, Shimizu I, Yoshida Y, Minamino T (2017) Metabolomic analysis in heart failure. Circ J 82:10–16

Article  PubMed  Google Scholar 

Deidda M, Piras C, Dessalvi CC, Locci E, Barberini L, Torri F, Ascedu F, Atzori L, Mercuro G (2015) Metabolomic approach to profile functional and metabolic changes in heart failure. J Transl Med 13:297

Article  PubMed  PubMed Central  Google Scholar 

Zhou J, Chen X, Chen W, Zhong L, Cui M (2021) Comprehensive plasma metabolomic and lipidomic analyses reveal potential biomarkers for heart failure. Mol Cell Biochem 476:3449–3460

Article  CAS  PubMed  Google Scholar 

Zeppenfeld K, Tfelt-Hansen J, de Riva M, Winkel BG, Behr ER, Blom NA, Charron P, Corrado D, Dagres N, de Chillou C, Eckardt L, Friede T, Haugaa KH, Hocini M, Lambiase PD, Marijon E, Merino JL, Peichl P, Priori SG, Reichlin T, Schulz-Menger J, Sticherling C, Tzeis S, Verstrael A, Volterrani M, ESC Scientific Document Group (2022) 2022 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death. Eur Heart J 43:3997–4126

Article  PubMed  Google Scholar 

Al-Khatib SM, Stevenson WG, Ackerman MJ, Bryant WJ, Callans DJ, Curtis AB, Deal BJ, Dickfeld T, Field ME, Fonarow GC, Gillis AM, Granger CB, Hammill SC, Hlatky MA, Joglar JA, Kay GN, Matlock DD, Myerburg RJ, Page RL (2018) 2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: executive summary: a report of the American college of cardiology/American heart association task force on clinical practice guidelines and the heart rhythm society. Circulation 138:e210–e271

PubMed  Google Scholar 

Nogami A, Kurita T, Abe H, Ando K, Ishikawa T, Imai K, Usui A, Okishige K, Kusano K, Kumagai K, Goya M, Kobayashi Y, Shimizu A, Shimizu W, Shoda M, Sumitomo N, Seo Y, Takahashi A, Tada H, Naito S, Nakazato Y, Nishimura T, Nitta T, Niwano S, Hagiwara N, Murakawa Y, Yamane T, Aiba T, Inoue K, Iwasaki Y, Inden Y, Uno K, Ogano M, Kimura M, Sakamoto SI, Sasaki S, Satomi K, Shiga T, Suzuki T, Sekiguchi Y, Soejima K, Takagi M, Chinushi M, Nishi N, Noda T, Hachiya H, Mitsuno M, Mitsuhashi T, Miyauchi Y, Miyazaki A, Morimoto T, Yamasaki H, Aizawa Y, Ohe T, Kimura T, Tanemoto K, Tsutsui H, Mitamura H, JCS/JHRS Joint Working Group (2021) JCS/JHRS 2019 guideline on non-pharmacotherapy of cardiac arrhythmias. J Arrhythm 37:709–870

Article  PubMed  PubMed Central  Google Scholar 

Abdelhamid M, Rosano G, Metra M, Adamopoulos S, Böhm M, Chioncel O, Filippatos G, Jankowska EA, Lopatin Y, Lund L, Milicic D, Moura B, Ben Gal T, Ristic A, Rakisheva A, Savarese G, Mullens W, Piepoli M, Bayes-Genis A, Thum T, Anker SD, Seferovic P, Coats AJS (2022) Prevention of sudden death in heart failure with reduced ejection fraction: do we still need an implantable cardioverter-defibrillator for primary prevention? Eur J Heart Fail 24:1460–1466

Article  PubMed  Google Scholar 

Nishihara Y, Nishimori M, Sawa T, Uemura K, Nagai S, Todo S, Oota E, Odajima S, Takeuchi K, Ichikawa Y, Kintsu M, Yamauchi Y, Shiraki H, Yamashita K, Fukuda T, Hisamatsu E, Shimizu M, Hirata KI, Tanaka H (2024) Left ventricular reverse remodeling following initiation of sacubitril/valsartan for heart failure with reduced ejection fraction and low blood pressure. Heart Vessels 39:95–104

Article  PubMed  Google Scholar 

Aoyama D, Miyazaki S, Amaya N, Tama N, Hasegawa K, Nomura R, Tsuji T, Nakano A, Uzui H, Tada H (2024) Treatment with catheter ablation for patients with arrhythmia-induced cardiomyopathy caused by atrial fibrillation promises a good prognosis. Heart Vessels 39:240–251

Article  PubMed  Google Scholar 

Agulló L, García-Dorado D, Inserte J, Paniagua A, Pyrhonen P, Llevadot J, Soler-Soler J (1999) L-arginine limits myocardial cell death secondary to hypoxia-reoxygenation by a cGMP-dependent mechanism. Am J Physiol 276:H1574–H1580

PubMed  Google Scholar 

Chang YF (1982) Lysine metabolism in the human and the monkey: demonstration of pipecolic acid formation in the brain and other organs. Neurochem Res 7:577–588

Article  CAS  PubMed  Google Scholar 

Nemutlu E, Zhang S, Xu YZ, Terzic A, Zhong L, Dzeja PD, Cha YM (2015) Cardiac resynchronization therapy induces adaptive metabolic transitions in the metabolomic profile of heart failure. J Card Fail 21:460–469

Article  PubMed  PubMed Central  Google Scholar 

Hiraiwa H, Okumura T, Kondo T, Kato T, Kazama S, Kimura Y, Ishihara T, Iwata E, Shimojo M, Kondo S, Aoki S, Kanzaki Y, Tanimura D, Sano H, Awaji Y, Yamada S, Murohara T (2021) Prognostic value of leucine/phenylalanine ratio as an amino acid profile of heart failure. Heart Vessels 36:965–977

Article  PubMed  Google Scholar 

Diakos NA, Navankasattusas S, Abel ED, Rutter J, McCreath L, Ferrin P, McKellar SH, Miller DV, Park SY, Richardson RS, Deberardinis R, Cox JE, Kfoury AG, Selzman CH, Stehlik J, Fang JC, Li DY, Drakos SG (2016) Evidence of glycolysis up-regulation and pyruvate mitochondrial oxidation mismatch during mechanical unloading of the failing human heart: implications for cardiac reloading and conditioning. JACC Basic Transl Sci 1:432–444

Article  PubMed  PubMed Central  Google Scholar 

Müller OJ, Heckmann MB, Ding L, Rapti K, Rangrez AY, Gerken T, Christiansen N, Rennefahrt UEE, Witt H, González Maldonado S, Ternes P, Schwab DM, Ruf T, Hille S, Remes A, Jungmann A, Weis TM, Kreußer JS, Gröne HJ, Backs J, Schatz P, Katus HA, Frey N (2019) Comprehensive plasma and tissue profiling reveals systemic metabolic alterations in cardiac hypertrophy and failure. Cardiovasc Res 115:1296–1305

Article  PubMed  Google Scholar 

Ahmad T, Kelly JP, McGarrah RW, Hellkamp AS, Fiuzat M, Testani JM, Wang TS, Verma A, Samsky MD, Donahue MP, Ilkayeva OR, Bowles DE, Patel CB, Milano CA, Rogers JG, Felker GM, O’Connor CM, Shah SH, Kraus WE (2016) prognostic implications of long-chain acylcarnitines in heart failure and reversibility with mechanical circulatory support. J Am Coll Cardiol 67:291–299

Article  CAS  PubMed  PubMed Central  Google Scholar 

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