Arpa G, Fassan M, Guerini C, et al. Claudin-18 expression in small bowel adenocarcinoma: a clinico-pathologic study. Virchows Arch. 2022;481:853–63.
Article CAS PubMed PubMed Central Google Scholar
Bouvier AM, Robaszkiewicz M, Jooste V, et al. Trends in incidence of small bowel cancer according to histology: a population-based study. J Gastroenterol. 2020;55:181–8.
Article CAS PubMed Google Scholar
Aparicio T, Zaanan A, Svrcek M, et al. Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment. Dig Liver Dis. 2014;46:97–104.
Vanoli A, Di Sabatino A, Furlan D, et al. Small bowel carcinomas in coeliac or Crohn’s disease: clinico-pathological, molecular, and prognostic features. A study from the Small Bowel Cancer Italian Consortium. J Crohns Colitis. 2017;11:942–53.
Vanoli A, Di Sabatino A, Martino M, et al. Small bowel carcinomas in celiac or Crohn’s disease: distinctive histophenotypic, molecular and histogenetic patterns. Mod Pathol. 2017;30:1453–66.
Article CAS PubMed Google Scholar
Neri G, Arpa G, Guerini C, et al. Small bowel adenocarcinomas featuring special AT-rich sequence-binding protein 2 (SATB2) expression and a colorectal cancer-like immunophenotype: a potential diagnostic pitfall. Cancers (Basel). 2020;12:3441.
Article CAS PubMed Google Scholar
Giuffrida P, Arpa G, Grillo F, et al. PD-L1 in small bowel adenocarcinoma is associated with etiology and tumor-infiltrating lymphocytes, in addition to microsatellite instability. Mod Pathol. 2020;33:1398–409.
Article CAS PubMed Google Scholar
Giuffrida P, Vanoli A, Arpa G, et al. Small bowel carcinomas associated with immune-mediated intestinal disorders: the current knowledge. Cancers (Basel). 2018;11:31.
Locher C, Batumona B, Afchain P, et al. Small bowel adenocarcinoma: French intergroup clinical practice guidelines for diagnosis, treatments and follow-up. Dig Liver Dis. 2018;50:15–9.
Benson AB, Venook AP, Al-Hawary MM, et al. Small bowel adenocarcinoma, version 1.2020, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2019;17:1109–33.
Article PubMed PubMed Central Google Scholar
Schrock AB, Devoe CE, McWilliams R, et al. Genomic profiling of small-bowel adenocarcinoma. JAMA Oncol. 2017;3:1546–53.
Article PubMed PubMed Central Google Scholar
Tatsuguchi A, Yamada T, Ueda K, et al. Genetic analysis of Japanese patients with small bowel adenocarcinoma using next-generation sequencing. BMC Cancer. 2022;22:723.
Article CAS PubMed PubMed Central Google Scholar
Lebwohl B, Sanders DS, Green PHR. Coeliac disease. Lancet. 2018;391:70–81.
Biagi F, Corazza GR. Mortality in celiac disease. Nat Rev Gastroenterol Hepatol. 2010;7:158–62.
Biagi F, Schiepatti A, Maiorano G, et al. Risk of complications in coeliac patients depends on age at diagnosis and type of clinical presentation. Dig Liver Dis. 2018;50:549–52.
Biagi F, Marchese A, Ferretti F, et al. A multicentre case control study on complicated coeliac disease: two different patterns of natural history, two different prognoses. BMC Gastroenterol. 2014;14:139.
Article PubMed PubMed Central Google Scholar
Emilsson L, Semrad C, Lebwohl B, et al. Risk of small bowel adenocarcinoma, adenomas, and carcinoids in a nationwide cohort of individuals with celiac disease. Gastroenterology. 2020;159:1686–94.
Rizzo F, Vanoli A, Sahnane N, et al. Small-bowel carcinomas associated with celiac disease: transcriptomic profiling shows predominance of microsatellite instability-immune and mesenchymal subtypes. Virchows Arch. 2020;476:711–23.
Article CAS PubMed Google Scholar
Xu X, Yu T, Wang Z. Discoidin domain receptor 2: a new target in cancer. Oncol Res Treat. 2022;45:205–15.
Article CAS PubMed Google Scholar
Tu MM, Lee FYF, Jones RT, et al. Targeting DDR2 enhances tumor response to anti-PD-1 immunotherapy. Sci Adv. 2019;5:eaav2437.
Article CAS PubMed PubMed Central Google Scholar
Lafitte M, Sirvent A, Roche S. Collagen kinase receptors as potential therapeutic targets in metastatic colon cancer. Front Oncol. 2020;10:125.
Article PubMed PubMed Central Google Scholar
Murray CW, Berdini V, Buck IM, et al. Fragment-based discovery of potent and selective DDR1/2 inhibitors. ACS Med Chem Lett. 2015;6:798–803.
Article CAS PubMed PubMed Central Google Scholar
Grither WR, Longmore GD. Inhibition of tumor-microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain. Proc Natl Acad Sci U S A. 2018;115:E7786–94.
Article CAS PubMed PubMed Central Google Scholar
Wang H, Guo M, Wei H, et al. Targeting p53 pathways: mechanisms, structures, and advances in therapy. Sig Transduct Target Ther. 2023;8:92.
Corrao G, Corazza GR, Bagnardi V, et al. Mortality in patients with coeliac disease and their relatives: a cohort study. Lancet. 2001;358:356–61.
Article CAS PubMed Google Scholar
Elfström P, Granath F, Ye W, et al. Low risk of gastrointestinal cancer among patients with celiac disease, inflammation, or latent celiac disease. Clin Gastroenterol Hepatol. 2012;10:30–6.
Schiepatti A, Maimaris S, Raju SA, et al. Persistent villous atrophy predicts development of complications and mortality in adult patients with coeliac disease: a multicentre longitudinal cohort study and development of a score to identify high-risk patients. Gut. 2023;72:2095–102.
Howdle PD, Jalal PK, Holmes GK, et al. Primary small-bowel malignancy in the UK and its association with coeliac disease. QJM. 2003;96:345–53.
Article CAS PubMed Google Scholar
Schiepatti A, Rej A, Maimaris S, et al. Clinical classification and long-term outcomes of seronegative coeliac disease: a 20-year multicentre follow-up study. Aliment Pharmacol Ther. 2021;54:1278–89.
Article CAS PubMed PubMed Central Google Scholar
Di Sabatino A, Biagi F, Gobbi PG, et al. How I treat enteropathy-associated T-cell lymphoma. Blood. 2012;119:2458–68.
Overman MJ, Hu CY, Kopetz S, et al. A population-based comparison of adenocarcinoma of the large and small intestine: insights into a rare disease. Ann Surg Oncol. 2012;19:1439–45.
Subbiah V, Kurzrock R. Universal germline and tumor genomic testing needed to win the war against cancer: genomics is the diagnosis. J Clin Oncol. 2023;4:3100–3.
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