Dick SA, Macklin JA, Nejat S, Momen A, Clemente-Casares X, Althagafi MG, et al. Self-renewing resident cardiac macrophages limit adverse remodeling following myocardial infarction. Nat Immunol. 2019;20:29–39. https://doi.org/10.1038/s41590-018-0272-2.
Article CAS PubMed Google Scholar
Tarkin JM, Calcagno C, Dweck MR, Evans NR, Chowdhury MM, Gopalan D, et al. (68)Ga-DOTATATE PET identifies residual myocardial inflammation and bone marrow activation after myocardial infarction. J Am Coll Cardiol. 2019;73:2489–91. https://doi.org/10.1016/j.jacc.2019.02.052.
Article PubMed PubMed Central Google Scholar
Hess A, Borchert T, Ross TL, Bengel FM, Thackeray JT. Characterizing the transition from immune response to tissue repair after myocardial infarction by multiparametric imaging. Basic Res Cardiol. 2022;117:14. https://doi.org/10.1007/s00395-022-00922-x.
Article CAS PubMed PubMed Central Google Scholar
Gabriel-Costa D. The pathophysiology of myocardial infarction-induced heart failure. Pathophysiology. 2018;25:277–84. https://doi.org/10.1016/j.pathophys.2018.04.003.
Article CAS PubMed Google Scholar
Nielsen R, Moller N, Gormsen LC, Tolbod LP, Hansson NH, Sorensen J, et al. Cardiovascular effects of treatment with the ketone body 3-hydroxybutyrate in chronic heart failure patients. Circulation. 2019;139:2129–41. https://doi.org/10.1161/CIRCULATIONAHA.118.036459.
Article CAS PubMed PubMed Central Google Scholar
Hess A, Derlin T, Koenig T, Diekmann J, Wittneben A, Wang Y, et al. Molecular imaging-guided repair after acute myocardial infarction by targeting the chemokine receptor CXCR4. Eur Heart J. 2020;41:3564–75. https://doi.org/10.1093/eurheartj/ehaa598.
Article CAS PubMed Google Scholar
Nahrendorf M, Hoyer FF, Meerwaldt AE, van Leent MMT, Senders ML, Calcagno C, et al. Imaging cardiovascular and lung macrophages with the positron emission tomography sensor (64)Cu-Macrin in mice, rabbits, and pigs. Circ Cardiovasc Imaging. 2020;13:e010586. https://doi.org/10.1161/CIRCIMAGING.120.010586.
Article PubMed PubMed Central Google Scholar
Santos-Zas I, Lemarie J, Zlatanova I, Cachanado M, Seghezzi JC, Benamer H, et al. Cytotoxic CD8(+) T cells promote granzyme B-dependent adverse post-ischemic cardiac remodeling. Nat Commun. 2021;12:1483. https://doi.org/10.1038/s41467-021-21737-9.
Article CAS PubMed PubMed Central Google Scholar
Santos-Zas I, Lemarie J, Tedgui A, Ait-Oufella H. Adaptive immune responses contribute to post-ischemic cardiac remodeling. Front Cardiovasc Med. 2018;5:198. https://doi.org/10.3389/fcvm.2018.00198.
Article CAS PubMed Google Scholar
Zeglinski MR, Granville DJ. Granzymes in cardiovascular injury and disease. Cell Signal. 2020;76:109804. https://doi.org/10.1016/j.cellsig.2020.109804.
Article CAS PubMed Google Scholar
Santiago L, Castro M, Sanz-Pamplona R, Garzon M, Ramirez-Labrada A, Tapia E, et al. Extracellular granzyme A promotes colorectal cancer development by enhancing gut inflammation. Cell Rep. 2020;32:107847. https://doi.org/10.1016/j.celrep.2020.107847.
Article CAS PubMed Google Scholar
Zhou H, Wang Y, Xu H, Shen X, Zhang T, Zhou X, et al. Noninvasive interrogation of CD8+ T cell effector function for monitoring early tumor responses to immunotherapy. J Clin Invest. 2022;132:e161065. https://doi.org/10.1172/JCI161065.
Article CAS PubMed PubMed Central Google Scholar
Tian J, Zheng Y, Mou T, Yun M, Tian Y, Lu Y, et al. Metformin confers longitudinal cardiac protection by preserving mitochondrial homeostasis following myocardial ischemia/reperfusion injury. Eur J Nucl Med Mol Imaging. 2023;50:825–38. https://doi.org/10.1007/s00259-022-06008-z.
Article CAS PubMed Google Scholar
Ke DQ, Chen ZY, Li ZL, Huang X, Liang H. Target inhibition of caspase-8 alleviates brain damage after subarachnoid hemorrhage. Neural Regen Res. 2020;15:1283–9. https://doi.org/10.4103/1673-5374.272613.
Article CAS PubMed PubMed Central Google Scholar
Hu S, Gao Y, Gao R, Wang Y, Qu Y, Yang J, et al. The selective STING inhibitor H-151 preserves myocardial function and ameliorates cardiac fibrosis in murine myocardial infarction. Int Immunopharmacol. 2022;107:108658. https://doi.org/10.1016/j.intimp.2022.108658.
Article CAS PubMed Google Scholar
Swirski FK, Nahrendorf M. Cardioimmunology: the immune system in cardiac homeostasis and disease. Nat Rev Immunol. 2018;18:733–44. https://doi.org/10.1038/s41577-018-0065-8.
Article CAS PubMed Google Scholar
Boukouaci W, Lauden L, Siewiera J, Dam N, Hocine H-R, Khaznadar Z, et al. Natural killer cell crosstalk with allogeneic human cardiac-derived stem/progenitor cells controls persistence. Cardiovasc Res. 2014;104:290–302. https://doi.org/10.1093/cvr/cvu208.
Article CAS PubMed Google Scholar
Martinez FJ, Collard HR, Pardo A, Raghu G, Richeldi L, Selman M, et al. Idiopathic pulmonary fibrosis. Nat Rev Dis Primers. 2017;3:17074. https://doi.org/10.1038/nrdp.2017.74.
Saito Y, Kondo H, Hojo Y. Granzyme B as a novel factor involved in cardiovascular diseases. J Cardiol. 2011;57:141–7. https://doi.org/10.1016/j.jjcc.2010.10.001.
Abbate A, Kontos MC, Grizzard JD, Biondi-Zoccai GG, Van Tassell BW, Robati R, et al. Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study). Am J Cardiol. 2010;105:1371-7 e1. https://doi.org/10.1016/j.amjcard.2009.12.059.
Article CAS PubMed Google Scholar
Ilatovskaya DV, Pitts C, Clayton J, Domondon M, Troncoso M, Pippin S, et al. CD8(+) T-cells negatively regulate inflammation post-myocardial infarction. Am J Physiol Heart Circ Physiol. 2019;317:H581–96. https://doi.org/10.1152/ajpheart.00112.2019.
Article CAS PubMed PubMed Central Google Scholar
Gao S, Li X, Jiang Q, Liang Q, Zhang F, Li S, et al. PKM2 promotes pulmonary fibrosis by stabilizing TGF-beta1 receptor I and enhancing TGF-beta1 signaling. Sci Adv. 2022;8:eabo0987. https://doi.org/10.1126/sciadv.abo0987.
Article CAS PubMed PubMed Central Google Scholar
Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, et al. Imaging systemic inflammatory networks in ischemic heart disease. J Am Coll Cardiol. 2015;65:1583–91. https://doi.org/10.1016/j.jacc.2015.02.034.
Article PubMed PubMed Central Google Scholar
Hicks RJ, Roselt PJ, Kallur KG, Tothill RW, Mileshkin L. FAPI PET/CT: will it end the hegemony of (18)F-FDG in oncology? J Nucl Med. 2021;62:296–302. https://doi.org/10.2967/jnumed.120.256271.
Article CAS PubMed Google Scholar
Adrain C, Murphy BM, Martin SJ. Molecular ordering of the caspase activation cascade initiated by the cytotoxic T lymphocyte/natural killer (CTL/NK) protease granzyme B. J Biol Chem. 2005;280:4663–73. https://doi.org/10.1074/jbc.M410915200.
Article CAS PubMed Google Scholar
Ikemoto T, Hojo Y, Kondo H, Takahashi N, Hirose M, Nishimura Y, et al. Plasma granzyme B as a predicting factor of coronary artery disease–clinical significance in patients with chronic renal failure. J Cardiol. 2009;54:409–15. https://doi.org/10.1016/j.jjcc.2009.06.009.
Kondo H, Hojo Y, Tsuru R, Nishimura Y, Shimizu H, Takahashi N, et al. Elevation of plasma granzyme B levels after acute myocardial infarction. Circ J. 2009;73:503–7. https://doi.org/10.1253/circj.cj-08-0668.
Article CAS PubMed Google Scholar
Carrick D, Haig C, Rauhalammi S, Ahmed N, Mordi I, McEntegart M, et al. Pathophysiology of LV remodeling in survivors of STEMI: inflammation, remote myocardium, and prognosis. JACC Cardiovasc Imaging. 2015;8:779–89. https://doi.org/10.1016/j.jcmg.2015.03.007.
Article PubMed PubMed Central Google Scholar
Zhao S. Letter to the editor: is it time for imaging to level with pathology? Int J Cardiovasc Imaging. 2020;36:2249–50. https://doi.org/10.1007/s10554-020-01936-z.
De Villiers C, Riley PR. Mouse models of myocardial infarction: comparing permanent ligation and ischaemia-reperfusion. Dis Model Mech. 2020;13:dmm046565. https://doi.org/10.1242/dmm.046565.
Article CAS PubMed PubMed Central Google Scholar
De Celle T, Cleutjens JP, Blankesteijn WM, Debets JJ, Smits JF, Janssen BJ. Long-term structural and functional consequences of cardiac ischaemia-reperfusion injury in vivo in mice. Exp Physiol. 2004;89:605–15. https://doi.org/10.1113/expphysiol.2004.027649.
El-Mesallamy HO, Hamdy NM, El-Etriby AK, Wasfey EF. Plasma granzyme B in ST elevation myocardial infarction versus non-ST elevation acute coronary syndrome: comparisons with IL-18 and fractalkine. Mediators Inflamm. 2013;2013:343268. https://doi.org/10.1155/2013/343268.
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