Calcium channel blockers may reduce the development of long COVID in females

Bechman K, Yates M, Mann K, Nagra D, Smith LJ, Rutherford AI, et al. Inpatient COVID-19 mortality has reduced over time: results from an observational cohort. PLOS One. 2022;17:e0261142.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Callard F, Perego E. How and why patients made long COVID. Soc Sci Med. 2021;268:113426.

Article  PubMed  PubMed Central  Google Scholar 

Blomberg B, Mohn KG, Brokstad KA, Zhou F, Linchausen DW, Hansen BA, et al. Long COVID in a prospective cohort of home-isolated patients. Nat Med. 2021;27:1607–13.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Whitaker M, Elliott J, Chadeau-Hyam M, Riley S, Darzi A, Cooke G, et al. Persistent COVID-19 symptoms in a community study of 606,434 people in England. Nat Commun. 2022;13:1957.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sudre CH, Murray B, Varsavsky T, Graham MS, Penfold RS, Bowyer RC, et al. Attributes and predictors of long COVID. Nat Med. 2021;27:626–31.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Groff D, Sun A, Ssentongo AE, Ba DM, Parsons N, Poudel GR, et al. Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection: a systematic review. JAMA Netw Open. 2021;4:e2128568.

Article  PubMed  PubMed Central  Google Scholar 

Nasserie T, Hittle M, Goodman SN. Assessment of the frequency and variety of persistent symptoms among patients with COVID-19: a systematic review. JAMA Netw Open. 2021;4:e2111417.

Article  PubMed  PubMed Central  Google Scholar 

Pływaczewska-Jakubowska M, Chudzik M, Babicki M, Kapusta J, Jankowski P. Lifestyle, course of COVID-19, and risk of Long-COVID in non-hospitalized patients. Front Med. 2022;9:1036556.

Article  Google Scholar 

Pazukhina E, Andreeva M, Spiridonova E, Bobkova P, Shikhaleva A, El-Taravi Y, et al. Prevalence and risk factors of post-COVID-19 condition in adults and children at 6 and 12 months after hospital discharge: a prospective, cohort study in Moscow (StopCOVID). BMC Med. 2022;20:244.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Fernández-de-Las-Peñas C, Torres-Macho J, Velasco-Arribas M, Plaza-Canteli S, Arias-Navalón JA, Hernández-Barrera V, et al. Preexisting hypertension is associated with a greater number of long-term post-COVID symptoms and poor sleep quality: a case-control study. J Hum Hypertens. 2022;36:582–4.

Article  PubMed  PubMed Central  Google Scholar 

Tleyjeh IM, Saddik B, Ramakrishnan RK, AlSwaidan N, AlAnazi A, Alhazmi D, et al. Long term predictors of breathlessness, exercise intolerance, chronic fatigue and well-being in hospitalized patients with COVID-19: a cohort study with 4 months median follow-up. J Infect Public Health. 2022;15:21–28.

Article  PubMed  Google Scholar 

Tleyjeh IM, Saddik B, AlSwaidan N, AlAnazi A, Ramakrishnan RK, Alhazmi D, et al. Prevalence and predictors of post-acute COVID-19 Syndrome (PACS) after hospital discharge: a cohort study with 4 months median follow-up. PLOS One. 2021;16:e0260568.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Subramanian A, Nirantharakumar K, Hughes S, Myles P, Williams T, Gokhale KM, et al. Symptoms and risk factors for long COVID in non-hospitalized adults. Nat Med. 2022;28:1706–14.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Terai H, Ishii M, Takemura R, Namkoong H, Shimamoto K, Masaki K, et al. Comprehensive analysis of long COVID in a Japanese nationwide prospective cohort study. Respir Investig. 2023;30:802-814.

Ishii M, Terai H, Kabata H, Masaki K, Chubachi S, Tateno H, et al. Clinical characteristics of 345 patients with coronavirus disease 2019 in Japan: a multicenter retrospective study. J Infect. 2020;81:e3–e5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Dessie ZG, Zewotir T. Mortality-related risk factors of COVID-19: a systematic review and meta-analysis of 42 studies and 423,117 patients. BMC Infect Dis. 2021;21:855.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Adjei S, Hong K, Molinari NM, Bull-Otterson L, Ajani UA, Gundlapalli AV, et al. Mortality risk among patients hospitalized primarily for COVID-19 during the omicron and delta variant pandemic periods - United States, April 2020–June 2022. Morb Mortal Wkly Rep. 2022;71:1182–9.

Article  Google Scholar 

Otake S, Chubachi S, Namkoong H, Nakagawara K, Tanaka H, Lee H, et al. Clinical clustering with prognostic implications in Japanese COVID-19 patients: report from Japan COVID-19 Task Force, a nation-wide consortium to investigate COVID-19 host genetics. BMC Infect Dis. 2022;22:735.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhang LK, Sun Y, Zeng H, Wang Q, Jiang X, Shang WJ, et al. Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension. Cell Discov. 2020;6:96.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Solaimanzadeh I. Nifedipine and amlodipine are associated with improved mortality and decreased risk for intubation and mechanical ventilation in elderly patients hospitalized for COVID-19. Cureus. 2020;12:e8069.

PubMed  PubMed Central  Google Scholar 

Guo X, Zhu Y, Hong Y. Decreased mortality of COVID-19 with renin-angiotensin-aldosterone system inhibitors therapy in patients with hypertension: a meta-analysis. Hypertension. 2020;76:e13–e14.

Article  CAS  PubMed  Google Scholar 

Nakagawara K, Namkoong H, Terai H, Masaki K, Tanosaki T, Shimamoto K, et al. Comprehensive and long-term surveys of COVID-19 sequelae in Japan, an ambidirectional multicentre cohort study: study protocol. BMJ Open Respir Res. 2021;8:e001015.

Article  PubMed  PubMed Central  Google Scholar 

Centers for Disease Control and Prevention (CDC). https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html.

Bucciarelli V, Nasi M, Bianco F, Seferovic J, Ivkovic V, Gallina S, et al. Depression pandemic and cardiovascular risk in the COVID-19 era and long COVID syndrome: gender makes a difference. Trends Cardiovasc Med. 2022;32:12–17.

Article  CAS  PubMed  Google Scholar 

Fernández-de-Las-Peñas C, Martín-Guerrero JD, Pellicer-Valero ÓJ, Navarro-Pardo E, Gómez-Mayordomo V, Cuadrado ML, et al. Female sex is a risk factor associated with long-term post-COVID related-symptoms but not with COVID-19 symptoms: the LONG-COVID-EXP-CM multicenter study. J Clin Med. 2022;11:413.

Article  PubMed  PubMed Central  Google Scholar 

Lee H, Chubachi S, Namkoong H, Asakura T, Tanaka H, Otake S, et al. Characteristics of hospitalized patients with COVID-19 during the first to fifth waves of infection: a report from the Japan COVID-19 Task Force. BMC Infect Dis. 2022;22:935.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Jose RJ, Manuel A. COVID-19 cytokine storm: the interplay between inflammation and coagulation. Lancet Respir Med. 2020;8:e46–e47.

Article  CAS  PubMed  Google Scholar 

Hossain MA, Hossain KMA, Saunders K, Uddin Z, Walton LM, Raigangar V, et al. Prevalence of Long COVID symptoms in Bangladesh: a prospective inception cohort study of COVID-19 survivors. BMJ Glob Health. 2021;6:e006838.

Article  PubMed  Google Scholar 

Crook H, Raza S, Nowell J, Young M, Edison P. Long covid-mechanisms, risk factors, and management. BMJ. 2021;374:n1648.

Article  PubMed  Google Scholar 

Antonelli M, Pujol JC, Spector TD, Ourselin S, Steves CJ. Risk of long COVID associated with delta versus omicron variants of SARS-CoV-2. Lancet. 2022;399:2263–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wise J. Covid-19: long covid risk is lower with omicron than delta, researchers find. BMJ. 2022;377:o1500.

Article  PubMed  Google Scholar 

Sheppard JP, Nicholson BD, Lee J, McGagh D, Sherlock J, Koshiaris C, et al. Association between blood pressure control and coronavirus disease 2019 outcomes in 45 418 symptomatic patients with hypertension: an observational cohort study. Hypertension. 2021;77:846–55.

Article  CAS  PubMed  Google Scholar 

Fang L, Karakiulakis G, Roth M. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? Lancet Respir Med. 2020;8:e21.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nozari F, Hamidizadeh N. The effects of different classes of antihypertensive drugs on patients with COVID-19 and hypertension: a mini-review. Int J Hypertens. 2022;2022:5937802.

Article  PubMed  PubMed Central  Google Scholar 

Nalbandian A, Sehgal K, Gupta A, Madhavan MV, McGroder C, Stevens JS, et al. Post-acute COVID-19 syndrome. Nat Med. 2021;27:601–15.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ohyama M, Matsudo K, Fujita T. Management of hair loss after severe acute respiratory syndrome coronavirus 2 infection: insight into the pathophysiology with implication for better management. J Dermatol. 2022;49:939–47.

Article  CAS  PubMed  PubMed Central 

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