Allahverdian S, Chehroudi AC, McManus BM et al (2014) Contribution of intimal smooth muscle cells to cholesterol accumulation and macrophage-like cells in human atherosclerosis. Circulation 129(15):1551–1559

Article  CAS  PubMed  Google Scholar 

Bengmark S, Mesa MD, Gil A (2009) Plant-derived health: the effects of turmeric and curcuminoids. Nutricion hospitalaria 24(3):273–81

CAS  PubMed  Google Scholar 

Bennett MR, Sinha S, Owens GK (2016) Vascular smooth muscle cells in atherosclerosis. Circ Res 118(4):692–702

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cicero AFG, Kuwabara M, Johnson R et al (2018) LDL-oxidation, serum uric acid, kidney function and pulse-wave velocity: Data from the Brisighella Heart Study cohort. Int J Cardiol 15(261):204–208

Article  Google Scholar 

Cicero AFG, Fogacci F, Giovannini M et al (2019) Interaction between low-density lipoprotein-cholesterolaemia, serum uric level and incident hypertension: data from the Brisighella Heart Study. J Hypertens 37(4):728–731

Article  CAS  PubMed  Google Scholar 

Dutzmann S, Schiborr C, Kocher A et al (2016) Intratumoral concentrations and effects of orally administered micellar curcuminoids in glioblastoma patients. Nutrition and Cancer 68(6):943–8

Article  PubMed  Google Scholar 

Gagliardi S, Truffi M, Tinelli V, et al. 2022 Bisdemethoxycurcumin (BDC)-Loaded H-Ferritin-Nanocages Mediate the Regulation of Inflammation in Alzheimer's Disease Patients. Int J Mol Sci 23(16).

Grootaert MO, da Costa Martins PA, Bitsch N et al (2015) Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis. Autophagy 11(11):2014–2032

Article  CAS  PubMed  PubMed Central  Google Scholar 

Herrington W, Lacey B, Sherliker P et al (2016) Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease. Circ Res 118(4):535–546

Article  CAS  PubMed  Google Scholar 

Hsiao YT, Kuo CL, Lin JJ, et al. (2018) Curcuminoids combined with gefitinib mediated apoptosis and autophagy of human oral cancer SAS cells in vitro and reduced tumor of SAS cell xenograft mice in vivo. Environmental toxicology

Joy T, Hegele RA (2008) Is raising HDL a futile strategy for atheroprotection? Nat Rev Drug Discovery 7(2):143–155

Article  CAS  PubMed  Google Scholar 

Khatana C, Saini NK, Chakrabarti S et al (2020) Mechanistic Insights into the Oxidized Low-Density Lipoprotein-Induced Atherosclerosis. Oxid Med Cell Longev 2020:5245308

Article  PubMed  PubMed Central  Google Scholar 

Kim GR, Cho SN, Kim HS et al (2016) Histone deacetylase and GATA-binding factor 6 regulate arterial remodeling in angiotensin II-induced hypertension. J Hypertens 34(11):2206–2219

Article  CAS  PubMed  Google Scholar 

Klionsky DJ (2007) Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 8(11):931–937

Article  CAS  PubMed  Google Scholar 

Komatsu K, Sasaki Y, Tanaka K et al (2008) Morphological, genetic, and chemical polymorphism of Curcuma kwangsiensis. J Nat Med 62(4):413–422

Article  CAS  PubMed  Google Scholar 

Kong R, Kang OH, Seo YS et al (2018) MAPKs and NFkappaB pathway inhibitory effect of bisdemethoxycurcumin on phorbol12myristate13acetate and A23187induced inflammation in human mast cells. Mol Med Rep 17(1):630–635

CAS  PubMed  Google Scholar 

Kumar S, Nanduri R, Bhagyaraj E et al (2021) Vitamin D3-VDR-PTPN6 axis mediated autophagy contributes to the inhibition of macrophage foam cell formation. Autophagy 17(9):2273–2289

Article  CAS  PubMed  Google Scholar 

Libby P, Bornfeldt KE, Tall AR (2016) Atherosclerosis: Successes, surprises, and future challenges. Circ Res 118(4):531–534

Article  CAS  PubMed  PubMed Central  Google Scholar 

Liu K, Czaja MJ (2013) Regulation of lipid stores and metabolism by lipophagy. Cell Death Differ 20(1):3–11

Article  PubMed  Google Scholar 

Liu Q, Wang YM, Gu HF (2020) Lipophagy in atherosclerosis. Clinica Chimica Acta 511:208–214

Article  CAS  Google Scholar 

Ouimet M, Marcel YL (2012) Regulation of lipid droplet cholesterol efflux from macrophage foam cells. Arterioscler Thromb Vasc Biol 32(3):575–581

Article  CAS  PubMed  Google Scholar 

Ouimet M, Franklin V, Mak E et al (2011) Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase. Cell Metab 13(6):655–667

Article  CAS  PubMed  PubMed Central  Google Scholar 

Qin L, Wang Z, Tao L et al (2010) ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy. Autophagy 6(2):239–247

Article  CAS  PubMed  Google Scholar 

Ringman JM, Frautschy SA, Cole GM et al (2005) A potential role of the curry spice curcumin in Alzheimer’s disease. Curr Alzheimer Res 2(2):131–136

Article  CAS  PubMed  PubMed Central  Google Scholar 

Shi Y, Jiang S, Zhao T et al (2020) Celastrol suppresses lipid accumulation through LXRalpha/ABCA1 signaling pathway and autophagy in vascular smooth muscle cells. Biochem Biophys Res Commun 532(3):466–474

Article  CAS  PubMed  Google Scholar 

Singh A, Srinivasan AK, Chakrapani LN et al (2019) LOX-1, the Common Therapeutic Target in Hypercholesterolemia: A New Perspective of Antiatherosclerotic Action of Aegeline. Oxid Med Cell Longev 2019:8285730

Article  PubMed  PubMed Central  Google Scholar 

Song Z, Guo Y, Zhou M et al (2014) The PI3K/p-Akt signaling pathway participates in calcitriol ameliorating podocyte injury in DN rats. Metabolism 63(10):1324–33

Article  CAS  PubMed  Google Scholar 

Thomes PG, Rasineni K, Yang L et al (2019) Ethanol withdrawal mitigates fatty liver by normalizing lipid catabolism. Am J Physiol Gastrointest Liver Physiol 316(4):G509–G518

Article  PubMed  PubMed Central  Google Scholar 

Wang L, Jiang Y, Song X et al (2016) Pdcd4 deficiency enhances macrophage lipoautophagy and attenuates foam cell formation and atherosclerosis in mice. Cell Death Dis 21(7):e2055

Article  Google Scholar 

Ward NC, Watts GF, Eckel RH (2019) Statin Toxicity. Circ Res 124(2):328–350

Article  CAS  PubMed  Google Scholar 

Wirka RC, Wagh D, Paik DT et al (2019) Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Nat Med 25(8):1280–1289

Article  CAS  PubMed  PubMed Central  Google Scholar 

Xiang M, Jiang HG, Shu Y et al (2020) Bisdemethoxycurcumin Enhances the Sensitivity of Non-small Cell Lung Cancer Cells to Icotinib via Dual Induction of Autophagy and Apoptosis. Int J Biol Sci 16(9):1536–1550

Article  CAS  PubMed  PubMed Central  Google Scholar 

Yeh CC, Su YH, Lin YJ et al (2015) Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis. Drug Des Dev Ther 9:2285–2300

Google Scholar 

Zachari M, Ganley IG (2017) The mammalian ULK1 complex and autophagy initiation. Essays Biochem 61(6):585–596

Article  PubMed  PubMed Central  Google Scholar 

Zhang J, Yang Y, Han H, et al. 2021 Bisdemethoxycurcumin attenuates lipopolysaccharide-induced intestinal damage through improving barrier integrity, suppressing inflammation, and modulating gut microbiota in broilers. J Animal Sci 99(11)

Zhang X, Zhong S (2020) PDK1 Inhibitor GSK-470 Exhibits Potent Anticancer Activity in a Pheochromocytoma PC12 Cell Tumor Model via Akt/mTOR Pathway. Anticancer Agents Med Chem 20(7):828–833

Article  CAS  PubMed  Google Scholar 

Zhou Y, Miles JR, Tavori H et al (2019) PMP22 Regulates Cholesterol Trafficking and ABCA1-Mediated Cholesterol Efflux. J Neurosci 39(27):5404–5418

Article  CAS  PubMed  PubMed Central  Google Scholar