Baigrie D, Nookala V (2022) Bullous pemphigoid. StatPearls. Treasure Island (FL)
Schmidt E, Della Torre R, Borradori L (2012) Clinical features and practical diagnosis of bullous pemphigoid. Immunol Allergy Clin 32(2):217–232
Endo M, Watanabe Y, Yamamoto M, Igari S, Kikuchi N, Yamamoto T (2021) Erythrodermic bullous pemphigoid. Dermatol Sin 39(1):61–62. https://doi.org/10.4103/ds.ds_45_20
Bernard P, Antonicelli F (2017) Bullous pemphigoid: a review of its diagnosis, associations and treatment. Am J Clin Dermatol 18(4):513–528. https://doi.org/10.1007/s40257-017-0264-2
Ren Z, Hsu DY, Brieva J, Silverberg NB, Langan SM, Silverberg JI (2017) Hospitalization, inpatient burden and comorbidities associated with bullous pemphigoid in the U.S.A. Br J Dermatol 176(1):87–99.https://doi.org/10.1111/bjd.14821
Chen Y, Wu C, Lin M, Chen T, Liao K, Chen Y et al (2011) Comorbidity profiles among patients with bullous pemphigoid: a nationwide population-based study. Br J Dermatol 165(3):593–599
Article CAS PubMed Google Scholar
Langan SM, Groves RW, West J (2011) The relationship between neurological disease and bullous pemphigoid: a population-based case–control study. J Invest Dermatol 131(3):631–636
Article CAS PubMed Google Scholar
Zeng FA, Wilson A, Sheriff T, Murrell DF (2022) Side effects of steroid-sparing agents in patients with bullous pemphigoid and pemphigus: a systematic review. JAAD international 9:33–43
Article PubMed PubMed Central Google Scholar
Cole C, Borradori L, Amber KT (2022) Deciphering the contribution of BP230 autoantibodies in bullous pemphigoid. Antibodies 11(3):44
Article CAS PubMed PubMed Central Google Scholar
Charneux J, Lorin J, Vitry F, Antonicelli F, Reguiai Z, Barbe C et al (2011) Usefulness of BP230 and BP180-NC16a enzyme-linked immunosorbent assays in the initial diagnosis of bullous pemphigoid: a retrospective study of 138 patients. Arch Dermatol 147(3):286–291
Thoma-Uszynski S, Uter W, Schwietzke S, Hofmann SC, Hunziker T, Bernard P et al (2004) BP230-and BP180-specific auto-antibodies in bullous pemphigoid. J Invest Dermatol 122(6):1413–1422
Article CAS PubMed Google Scholar
Yoshida M, Hamada T, Amagai M, Hashimoto K, Uehara R, Yamaguchi K et al (2006) Enzyme-linked immunosorbent assay using bacterial recombinant proteins of human BP230 as a diagnostic tool for bullous pemphigoid. J Dermatol Sci 41(1):21–30
Article CAS PubMed Google Scholar
Delgado JC, Turbay D, Yunis EJ, Yunis JJ, Morton ED, Bhol K et al (1996) A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid. Proc Natl Acad Sci 93(16):8569–8571
Article CAS PubMed PubMed Central Google Scholar
Schiavo AL, Ruocco E, Brancaccio G, Caccavale S, Ruocco V, Wolf R (2013) Bullous pemphigoid: etiology, pathogenesis, and inducing factors: facts and controversies. Clin Dermatol 31(4):391–399
Arakawa M, Dainichi T, Ishii N, Hamada T, Karashima T, Nakama T et al (2011) Lesional Th17 cells and regulatory T cells in bullous pemphigoid. Exp Dermatol 20(12):1022–1024
Article CAS PubMed Google Scholar
Moro F, Fania L, Sinagra JLM, Salemme A, Di Zenzo G (2020) Bullous pemphigoid: trigger and predisposing factors. Biomolecules 10(10):1432
Article CAS PubMed PubMed Central Google Scholar
Lin J-D, Hung S-J (2021) Radiation-induced bullous pemphigoid in a patient with Kaposi’s sarcoma. Dermatol Sin 39(3):159–160. https://doi.org/10.4103/ds.ds_23_21
Chao Y-C, Liu K-L (2022) New-onset bullous pemphigoid triggered by AstraZeneca COVID-19 vaccine. Dermatol Sin 40(4):245–246. https://doi.org/10.4103/1027-8117.358000
Genovese G, Di Zenzo G, Cozzani E, Berti E, Cugno M, Marzano AV (2019) New insights into the pathogenesis of bullous pemphigoid: 2019 update. Front Immunol 10:1506
Article CAS PubMed PubMed Central Google Scholar
Hiroyasu S, Turner CT, Richardson KC, Granville DJ (2019) Proteases in pemphigoid diseases Front Immunol 10:1454. https://doi.org/10.3389/fimmu.2019.01454
Article CAS PubMed Google Scholar
Ellebrecht CT, Maseda D, Payne AS (2022) Pemphigus and pemphigoid: from disease mechanisms to druggable pathways. J Invest Dermatol 142(3 Pt B):907–914.https://doi.org/10.1016/j.jid.2021.04.040
Cole C, Vinay K, Borradori L, Amber KT (2022) Insights into the pathogenesis of bullous pemphigoid: the role of complement-independent mechanisms. Front Immunol 13:912876. https://doi.org/10.3389/fimmu.2022.912876
Article CAS PubMed PubMed Central Google Scholar
Messingham KA, Noe MH, Chapman MA, Giudice GJ, Fairley JA (2009) A novel ELISA reveals high frequencies of BP180-specific IgE production in bullous pemphigoid. J Immunol Methods 346(1–2):18–25
Article CAS PubMed PubMed Central Google Scholar
Ishiura N, Fujimoto M, Watanabe R, Nakashima H, Kuwano Y, Yazawa N et al (2008) Serum levels of IgE anti-BP180 and anti-BP230 autoantibodies in patients with bullous pemphigoid. J Dermatol Sci 49(2):153–161
Article CAS PubMed Google Scholar
Mihai S, Chiriac MT, Herrero-González JE, Goodall M, Jefferis R, Savage CO et al (2007) IgG4 autoantibodies induce dermal–epidermal separation. J Cell Mol Med 11(5):1117–1128
Article CAS PubMed PubMed Central Google Scholar
Bernard P, Reguiai Z, Tancrede-Bohin E, Cordel N, Plantin P, Pauwels C et al (2009) Risk factors for relapse in patients with bullous pemphigoid in clinical remission: a multicenter, prospective, cohort study. Arch Dermatol 145(5):537–542. https://doi.org/10.1001/archdermatol.2009.53
Kalowska M, Ciepiela O, Kowalewski C, Demkow U, Schwartz RA, Wozniak K (2016) Enzyme-linked immunoassay index for anti-NC16a IgG and IgE auto-antibodies correlates with severity and activity of bullous pemphigoid. Acta Derm Venereol 96(2):191–196. https://doi.org/10.2340/00015555-2101
Article CAS PubMed Google Scholar
Zhou XP, Liu B, Xu Q, Yang Y, He CX, Zuo YG et al (2016) Serum levels of immunoglobulins G1 and G4 targeting the non-collagenous 16A domain of BP180 reflect bullous pemphigoid activity and predict bad prognosis. J Dermatol 43(2):141–148. https://doi.org/10.1111/1346-8138.13051
Article CAS PubMed Google Scholar
Asbrink E, Hovmark A (1984) Serum IgE levels in patients with bullous pemphigoid and its correlation to the activity of the disease and anti-basement membrane zone antibodies. Acta Derm Venereol 64(3):243–246
Article CAS PubMed Google Scholar
D’auria L, Pietravalle M, Mastroianni A, Ferraro C, Mussi A, Bonifati C et al (1998) IL-5 levels in the serum and blister fluid of patients with bullous pemphigoid: correlations with eosinophil cationic protein, RANTES, IgE and disease severity. Arch Dermatol Res 290(1–2):25–27
Ma L, Wang M, Wang X, Chen X, Zhu X (2015) Circulating IgE anti-BP180 autoantibody and its correlation to clinical and laboratorial aspects in bullous pemphigoid patients. J Dermatol Sci 78(1):76–77
Article CAS PubMed Google Scholar
Hiroyasu S, Barit JJG, Hiroyasu A, Tsuruta D (2022) Pruritogens in pemphigoid diseases: possible therapeutic targets for a burdensome symptom. J Dermatol. https://doi.org/10.1111/1346-8138.16652
Article PubMed PubMed Central Google Scholar
van Beek N, Luttmann N, Huebner F, Recke A, Karl I, Schulze FS et al (2017) Correlation of serum levels of IgE autoantibodies against BP180 with bullous pemphigoid disease activity. JAMA Dermatol 153(1):30–38. https://doi.org/10.1001/jamadermatol.2016.3357
Chiorean RM, Baican A, Mustafa MB, Lischka A, Leucuta DC, Feldrihan V et al (2018) Complement-activating capacity of autoantibodies correlates with disease activity in bullous pemphigoid patients. Front Immunol 9:2687. https://doi.org/10.3389/fimmu.2018.02687
Article CAS PubMed PubMed Central Google Scholar
Liu Z, Giudice GJ, Swartz SJ, Fairley JA, Till GO, Troy JL et al (1995) The role of complement in experimental bullous pemphigoid. J Clin Invest 95(4):1539–1544. https://doi.org/10.1172/JCI117826
Article CAS PubMed PubMed Central Google Scholar
Li Q, Ujiie H, Shibaki A, Wang G, Moriuchi R, Qiao HJ et al (2010) Human IgG1 monoclonal antibody against human collagen 17 noncollagenous 16A domain induces blisters via complement activation in experimental bullous pemphigoid model. J Immunol 185(12):7746–7755. https://doi.org/10.4049/jimmunol.1000667
Article CAS PubMed Google Scholar
Karsten CM, Beckmann T, Holtsche MM, Tillmann J, Tofern S, Schulze FS et al (2018) Tissue destruction in bullous pemphigoid can be complement independent and may be mitigated by C5aR2. Front Immunol 9:488
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