Aliev G et al (2003) Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease. Neurotox Res 5(7):491–504
Arnao V et al (2015) In patient’s with Parkinson disease, autonomic symptoms are frequent and associated with other non-motor symptoms. Clin Auton Res 25(5):301–307
Berg A et al (2022) Autonomic dysfunction in Parkinson’s disease: results from the Faroese Parkinson’s disease cohort. Neurosci Lett 785:136789
Article CAS PubMed Google Scholar
Bostantjopoulou S et al (2016) Self-reported autonomic symptoms in Parkinson’s disease: properties of the SCOPA-AUT scale. Hippokratia 20(2):115–120
CAS PubMed PubMed Central Google Scholar
Braak H et al (2003) Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging 24(2):197–211
Brockmann K et al (2011) GBA-associated PD presents with nonmotor characteristics. Neurology 77(3):276–280
Article CAS PubMed Google Scholar
Chaudhuri KR, Schapira AH (2009) Non-motor symptoms of Parkinson’s disease: dopaminergic pathophysiology and treatment. Lancet Neurol 8(5):464–474
Article CAS PubMed Google Scholar
Coon EA, Cutsforth-Gregory JK, Benarroch EE (2018) Neuropathology of autonomic dysfunction in synucleinopathies. Mov Disord 33(3):349–358
Cui J et al (2021) Activities of daily living as a longitudinal moderator of the effect of autonomic dysfunction on anxiety and depression of Parkinson’s patients. Brain Behav 11(8):e2297
Article PubMed PubMed Central Google Scholar
de la Torre JC (2000) Critically attained threshold of cerebral hypoperfusion: the CATCH hypothesis of Alzheimer’s pathogenesis. Neurobiol Aging 21(2):331–342
De Pablo-Fernandez E et al (2017) Association of autonomic dysfunction with disease progression and survival in parkinson disease. JAMA Neurol 74(8):970–976
Article PubMed PubMed Central Google Scholar
Forjaz MJ et al (2010) Assessing autonomic symptoms of Parkinson’s disease with the SCOPA-AUT: a new perspective from Rasch analysis. Eur J Neurol 17(2):273–279
Article CAS PubMed Google Scholar
Gray WK, Wood BH, Walker RW (2009) Do autonomic function tests in people with Parkinson’s disease predict survival rates at 7 years follow-up? Mov Disord 24(16):2432–2434
Hinkle JT et al (2018) Dopamine transporter availability reflects gastrointestinal dysautonomia in early Parkinson disease. Parkinsonism Relat Disord 55:8–14
Article PubMed PubMed Central Google Scholar
Jankovic J (2008) Parkinson’s disease: clinical features and diagnosis. J Neurol Neurosurg Psychiatry 79(4):368–376
Article CAS PubMed Google Scholar
Kendall PC et al (1976) The state-trait anxiety inventory: a systematic evaluation. J Consult Clin Psychol 44(3):406–412
Article CAS PubMed Google Scholar
Khoo TK et al (2013) The spectrum of nonmotor symptoms in early Parkinson disease. Neurology 80(3):276–281
Article PubMed PubMed Central Google Scholar
Kim JY et al (2017) Validation of the Korean version of the scale for outcomes in Parkinson’s disease-autonomic. J Mov Disord 10(1):29–34
Article PubMed PubMed Central Google Scholar
Ledda C et al (2022) Burden of caregiving for cardiovascular dysautonomia in Parkinson’s disease. Clin Auton Res 32(6):455–461
Article PubMed PubMed Central Google Scholar
Longardner K et al (2022) Differential impact of individual autonomic domains on clinical outcomes in Parkinson’s disease. J Neurol 269(10):5510–5520
Article PubMed PubMed Central Google Scholar
Marek K et al (2011) The Parkinson Progression Marker Initiative (PPMI). Prog Neurobiol. 95(4):629–35
Article PubMed Central Google Scholar
Merola A et al (2016) Orthostatic hypotension in Parkinson’s disease: does it matter if asymptomatic? Parkinsonism Relat Disord 33:65–71
Merola A et al (2018) Autonomic dysfunction in Parkinson’s disease: a prospective cohort study. Mov Disord 33(3):391–397
Nasreddine ZS et al (2005) The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc 53(4):695–699
Pazo JH, Belforte JE (2002) Basal ganglia and functions of the autonomic nervous system. Cell Mol Neurobiol 22(5–6):645–654
Article CAS PubMed Google Scholar
Petrucci S et al (2020) GBA-related Parkinson’s disease: dissection of genotype-phenotype correlates in a large Italian cohort. Mov Disord 35(11):2106–2111
Article CAS PubMed Google Scholar
Pilipovich AA et al (2022) Gastrointestinal dysfunction impact on life quality in a cohort of russian patients with Parkinson’s disease I-III H&Y stage. Parkinsons Dis 2022:1571801
CAS PubMed PubMed Central Google Scholar
Pilotto A et al (2019) Orthostatic hypotension and REM sleep behaviour disorder: impact on clinical outcomes in α-synucleinopathies. J Neurol Neurosurg Psychiatry 90(11):1257–1263
Pilotto A et al (2021) Association of orthostatic hypotension with cerebral atrophy in patients with Lewy body disorders. Neurology 97(8):e814–e824
Article CAS PubMed PubMed Central Google Scholar
Sklerov M et al (2020) Longitudinal change in autonomic symptoms predicts activities of daily living and depression in Parkinson’s disease. Clin Auton Res 30(3):223–230
Sklerov M et al (2022) Autonomic and depression symptoms in Parkinson’s disease: clinical evidence for overlapping physiology. J Parkinsons Dis 12(3):1059–1067
Article CAS PubMed Google Scholar
Stanković I et al (2019) Longitudinal assessment of autonomic dysfunction in early Parkinson’s disease. Parkinsonism Relat Disord 66:74–79
van Deursen DN et al (2020) Autonomic failure in Parkinson’s disease is associated with striatal dopamine deficiencies. J Neurol 267(7):1922–1930
Article PubMed PubMed Central Google Scholar
Vichayanrat E et al (2021) Lower urinary tract dysfunction in Parkinsonian syndromes. Neurol Sci 42(10):4045–4054
Visser M et al (2004) Assessment of autonomic dysfunction in Parkinson’s disease: the SCOPA-AUT. Mov Disord 19(11):1306–1312
Winge K et al (2005) Relationship between nigrostriatal dopaminergic degeneration, urinary symptoms, and bladder control in Parkinson’s disease. Eur J Neurol 12(11):842–850
Article CAS PubMed Google Scholar
Yeh TL et al (2006) Correlation between striatal dopamine D2/D3 receptor binding and cardiovascular activity in healthy subjects. Am J Hypertens 19(9):964–969
Article CAS PubMed Google Scholar
Yu Z, Li Y, The Parkinson’s Progression Markers (2021) Association of autonomic symptoms with cerebrospinal fluid biomarkers in Parkinson disease and scans without evidence of dopaminergic deficit. Medicine (Baltimore). 100(7):e24837
Article CAS PubMed PubMed Central Google Scholar
Zhou Z et al (2021) Characteristics of autonomic dysfunction in parkinson’s disease: a large chinese multicenter cohort study. Front Aging Neurosci 13:761044
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