Newman DJ, Cragg GM. Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/2019. J Nat Prod. 2020;83:770–803.
Article CAS PubMed Google Scholar
Qadri H, Haseeb Shah A, Mudasir Ahmad S, Alshehri B, Almilaibary A, Ahmad Mir M. Natural products and their semi-synthetic derivatives against antimicrobial-resistant human pathogenic bacteria and fungi. Saudi J Biol Sci. 2022;29:103376.
Article CAS PubMed PubMed Central Google Scholar
van den Broek PJ. Antimicrobial drugs, microorganisms, and phagocytes. Rev Infect Dis. 1989;11:213–45.
Chin KW, Michelle THL, Luang-In V, Ma NL. An overview of antibiotic and antibiotic resistance. Environ Adv 2022;11:100331.
Qi YK, Tang X, Wei NN, Pang CJ, Du SS, Wang K. Discovery, synthesis, and optimization of teixobactin, a novel antibiotic without detectable bacterial resistance. J Pept Sci. 2022;28:e3428.
Article CAS PubMed Google Scholar
Dang X, Wang G. Spotlight on the selected new antimicrobial innate immune peptides discovered during 2015-2019. Curr Top Med Chem. 2020;20:2984–98.
Article CAS PubMed PubMed Central Google Scholar
Wang Z, Koirala B, Hernandez Y, Zimmerman M, Park S, Perlin DS, et al. A naturally inspired antibiotic to target multidrug-resistant pathogens. Nature. 2022;601:606–11.
Article CAS PubMed PubMed Central Google Scholar
Wang Z, Koirala B, Hernandez Y, Zimmerman M, Brady SF. Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance. Science. 2022;376:991–6.
Article CAS PubMed Google Scholar
Dehbanipour R, Ghalavand Z. Anti-virulence therapeutic strategies against bacterial infections: recent advances. Germs. 2022;12:262–75.
Article CAS PubMed PubMed Central Google Scholar
Kalimuthu S, Alshanta OA, Krishnamoorthy AL, Pudipeddi A, Solomon AP, McLean W, et al. Small molecule based anti-virulence approaches against Candida albicans infections. Crit Rev Microbiol. 2022;48:743–69.
Article CAS PubMed Google Scholar
Ratledge C, Dover LG. Iron metabolism in pathogenic bacteria. Annu Rev Microbiol. 2000;54:881–941.
Article CAS PubMed Google Scholar
Miethke M, Marahiel MA. Siderophore-based iron acquisition and pathogen control. Microbiol Mol Biol Rev. 2007;71:413–51.
Article CAS PubMed PubMed Central Google Scholar
Bilitewski U, Blodgett JAV, Duhme-Klair AK, Dallavalle S, Laschat S, Routledge A, et al. Chemical and biological aspects of nutritional immunity-perspectives for new anti-infectives that target iron uptake systems. Angew Chem-Int Ed. 2017;56:14360–82.
Xie F, Dai SW, Zhao Y, Huang P, Yu S, Ren B, et al. Generation of fluorinated amychelin siderophores against Pseudomonas aeruginosa infections by a combination of genome mining and mutasynthesis. Cell Chem Biol. 2020;27:1532–43.
Article CAS PubMed Google Scholar
Kautsar SA, Blin K, Shaw S, Weber T, Medema MH. BiG-FAM: the biosynthetic gene cluster families database. Nucleic Acids Res. 2021;49:D490–7.
Article CAS PubMed Google Scholar
Bankevich A, Nurk S, Antipov D, Gurevich AA, Dvorkin M, Kulikov AS, et al. SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing. J Comput Biol. 2012;19:455–77.
Article CAS PubMed PubMed Central Google Scholar
Aziz RK, Bartels D, Best AA, DeJongh M, Disz T, Edwards RA, et al. The RAST Server: rapid annotations using subsystems technology. BMC Genom. 2008;9:75.
Blin K, Shaw S, Steinke K, Villebro R, Ziemert N, Lee SY, et al. antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline. Nucleic Acids Res. 2019;47:W81–7.
Article CAS PubMed PubMed Central Google Scholar
Emms DM, Kelly S. OrthoFinder: phylogenetic orthology inference for comparative genomics. Genome Biol. 2019;20:238.
Article PubMed PubMed Central Google Scholar
Chun J, Oren A, Ventosa A, Christensen H, Arahal DR, da Costa MS, et al. Proposed minimal standards for the use of genome data for the taxonomy of prokaryotes. Int J Syst Evol Microbiol. 2018;68:461–6.
Article CAS PubMed Google Scholar
Thorell K, Meier-Kolthoff JP, Sjöling Å, Martín-Rodríguez AJ. Whole-genome sequencing redefines Shewanella taxonomy. Front Microbiol. 2019;10:1861.
Article PubMed PubMed Central Google Scholar
Retamal-Morales G, Mehnert M, Schwabe R, Tischler D, Zapata C, Chávez R, et al. Detection of arsenic-binding siderophores in arsenic-tolerating Actinobacteria by a modified CAS assay. Ecotoxicol Environ Saf. 2018;157:176–81.
Article CAS PubMed Google Scholar
Frisch MJ, Trucks GW, Schlegel HB, Scuseria GE, Robb MA, Cheeseman JR, et al. Gaussian 16, Revision C.01. In: Gaussian I (ed): Wallingford CT, 2019.
Grimblat N, Zanardi MM, Sarotti AM. Beyond DP4: an improved probability for the stereochemical assignment of isomeric compounds using quantum chemical calculations of NMR shifts. J Org Chem. 2015;80:12526–34.
Article CAS PubMed Google Scholar
Aoyagi T, Hatsu M, Kojima F, Hayashi C, Hamada M, Takeuchi T. Benarthin - A new inhibitor of pyroglutamyl peptidase. 1. Taxonomy, fermentation, isolation and biological-activities. J Antibiot. 1992;45:1079–83.
Hatsu M, Naganawa H, Aoyagi T, Takeuchi T. Benarthin - A new inhibitor of pyroglutamyl peptidase. 2. Physicochemical properties and structure determination. J Antibiot. 1992;45:1084–7.
Hatsu M, Tuda M, Muraoka Y, Aoyagi T, Takeuchi T. Benarthin - A new inhibitor of pyroglutamyl peptidase. 3. synthesis and structure-activity-relationships. J Antibiot. 1992;45:1088–95.
Xu ZX, Li B, Tian Y, Li M, Dong JX, Zhang GJ. Chemical constituents from the aerial parts of Orychophragmus violaceus. Nat Prod Res. 2022;5:1–9.
Hider RC, Kong X. Chemistry and biology of siderophores. Nat Prod Rep. 2010;27:637–57.
Article CAS PubMed Google Scholar
Barry SM, Challis GL. Recent advances in siderophore biosynthesis. Curr Opin Chem Biol. 2009;13:205–15.
Article CAS PubMed Google Scholar
Timofeeva AM, Galyamova MR, Sedykh SE. Bacterial siderophores: classification, biosynthesis, perspectives of use in agriculture. Plants. 2022;11:3065.
Article CAS PubMed PubMed Central Google Scholar
Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM. Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death. Cell Host Microbe. 2013;13:406–16.
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