Suboptimal Cerebral Perfusion is Associated with Ischemia After Intracerebral Hemorrhage

Murthy SB, Cho SM, Gupta A, Shoamanesh A, Navi BB, Avadhani R, et al. A pooled analysis of diffusion-weighted imaging lesions in patients with acute intracerebral hemorrhage. JAMA Neurol. 2020;77(11):1390–7.

Article  PubMed  Google Scholar 

Prabhakaran S, Gupta R, Ouyang B, John S, Temes RE, Mohammad Y, et al. Acute brain infarcts after spontaneous intracerebral hemorrhage. Stroke. 2010;41(1):89–94.

Article  PubMed  Google Scholar 

Wu B, Yao X, Lei C, Liu M, Selim MH. Enlarged perivascular spaces and small diffusion-weighted lesions in intracerebral hemorrhage. Neurology. 2015;85(23):2045–52.

Article  PubMed  PubMed Central  Google Scholar 

Garg RK, Khan J, Dawe RJ, Conners J, John S, Prabhakaran S, et al. The influence of diffusion weighted imaging lesions on outcomes in patients with acute spontaneous intracerebral hemorrhage. Neurocrit Care. 2020;33(2):552–64.

Article  PubMed  PubMed Central  Google Scholar 

Kidwell CS, Rosand J, Norato G, Dixon S, Worrall BB, James ML, et al. Ischemic lesions, blood pressure dysregulation, and poor outcomes in intracerebral hemorrhage. Neurology. 2017;88(8):782–8.

Article  PubMed  PubMed Central  Google Scholar 

Shoamanesh A, Cassarly C, Morotti A, Romero JM, Oliveira-Filho J, Schlunk F, et al. Intensive blood pressure lowering and DWI lesions in intracerebral hemorrhage: exploratory analysis of the ATACH-2 randomized trial. Neurocrit Care. 2022;36(1):71–81.

Article  CAS  PubMed  Google Scholar 

Diedler J, Sykora M, Rupp A, Poli S, Karpel-Massler G, Sakowitz O, et al. Impaired cerebral vasomotor activity in spontaneous intracerebral hemorrhage. Stroke. 2009;40(3):815–9.

Article  PubMed  Google Scholar 

Jaeger M, Soehle M, Schuhmann MU, Meixensberger J. Clinical significance of impaired cerebrovascular autoregulation after severe aneurysmal subarachnoid hemorrhage. Stroke. 2012;43(8):2097–101.

Article  PubMed  Google Scholar 

Steiner LA, Czosnyka M, Piechnik SK, Smielewski P, Chatfield D, Menon DK, et al. Continuous monitoring of cerebrovascular pressure reactivity allows determination of optimal cerebral perfusion pressure in patients with traumatic brain injury. Crit Care Med. 2002;30(4):733–8.

Article  PubMed  Google Scholar 

Gupta VP, Garton ALA, Sisti JA, Christophe BR, Lord AS, Lewis AK, et al. Prognosticating functional outcome following intracerebral hemorrhage: the ICHOP score. World Neurosurg. 2017;101:577–83.

Article  PubMed  PubMed Central  Google Scholar 

Hemphill J. Claude, Greenberg Steven M., Anderson Craig S., Becker Kyra, Bendok Bernard R., Cushman Mary, et al. Guidelines for the management of spontaneous intracerebral hemorrhage. Stroke. 2015;46(7):2032–60.

Broderick J, Connolly S, Feldmann E, Hanley D, Kase C, Krieger D, et al. Guidelines for the management of spontaneous intracerebral hemorrhage in adults. Stroke. 2007;38(6):2001–23.

Article  PubMed  Google Scholar 

Morgenstern LB, Hemphill JC, Anderson C, Becker K, Broderick JP, Connolly ES, et al. Guidelines for the management of spontaneous intracerebral hemorrhage. Stroke. 2010;41(9):2108–29.

Article  PubMed  PubMed Central  Google Scholar 

Liu X, Maurits NM, Aries MJH, Czosnyka M, Ercole A, Donnelly J, et al. Monitoring of optimal cerebral perfusion pressure in traumatic brain injured patients using a multi-window weighting algorithm. J Neurotrauma. 2017;34(22):3081–8.

Article  PubMed  Google Scholar 

Aries MJH, Czosnyka M, Budohoski KP, Steiner LA, Lavinio A, Kolias AG, et al. Continuous determination of optimal cerebral perfusion pressure in traumatic brain injury. Crit Care Med. 2012;40(8):2456–63.

Article  PubMed  Google Scholar 

Sorrentino E, Diedler J, Kasprowicz M, Budohoski KP, Haubrich C, Smielewski P, et al. Critical thresholds for cerebrovascular reactivity after traumatic brain injury. Neurocrit Care. 2012;16(2):258–66.

Article  CAS  PubMed  Google Scholar 

Tas J, Beqiri E, van Kaam RC, Czosnyka M, Donnelly J, Haeren RH, et al. Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial. J Neurotrauma. 2021;38(20):2790–800.

Article  PubMed  Google Scholar 

Ma H, Guo ZN, Liu J, Xing Y, Zhao R, Yang Y. Temporal course of dynamic cerebral autoregulation in patients with intracerebral hemorrhage. Stroke. 2016;47(3):674–81.

Article  CAS  PubMed  Google Scholar 

Murthy SB, Diaz I, Wu X, Merkler AE, Iadecola C, Safford MM, et al. Risk of arterial ischemic events after intracerebral hemorrhage. Stroke. 2020;51(1):137–42.

Article  PubMed  Google Scholar 

Murthy SB, Zhang C, Gupta A, Cho SM, Lara LR, Avadhani R, et al. Diffusion-weighted imaging lesions after intracerebral hemorrhage and risk of stroke: a MISTIE III and ATACH-2 analysis. Stroke. 2021;52(2):595–602.

Article  PubMed  PubMed Central  Google Scholar 

Menon RS, Burgess RE, Wing JJ, Gibbons MC, Shara NM, Fernandez S, et al. Predictors of highly prevalent brain ischemia in intracerebral hemorrhage. Ann Neurol. 2012;71(2):199–205.

Article  PubMed  PubMed Central  Google Scholar 

Gioia LC, Kate M, Choi V, Sivakumar L, Jeerakathil T, Kosior J, et al. Ischemia in intracerebral hemorrhage is associated with leukoaraiosis and hematoma volume, not blood pressure reduction. Stroke. 2015;46(6):1541–7.

Article  PubMed  Google Scholar 

Garg RK, Liebling SM, Maas MB, Nemeth AJ, Russell EJ, Naidech AM. Blood pressure reduction, decreased diffusion on mri, and outcomes after intracerebral hemorrhage. Stroke J Cereb Circ. 2012;43(1):67–71.

Article  Google Scholar 

Qureshi AI, Huang W, Lobanova I, Barsan WG, Hanley DF, Hsu CY, et al. Outcomes of intensive systolic blood pressure reduction in patients with intracerebral hemorrhage and excessively high initial systolic blood pressure. JAMA Neurol. 2020;77(11):1–11.

Article  PubMed Central  Google Scholar 

Buletko AB, Thacker T, Cho SM, Mathew J, Thompson NR, Organek N, et al. Cerebral ischemia and deterioration with lower blood pressure target in intracerebral hemorrhage. Neurology. 2018;91(11):e1058–66.

Article  PubMed  Google Scholar 

Strandgaard S. Autoregulation of cerebral blood flow in hypertensive patients: the modifying influence of prolonged antihypertensive treatment on the tolerance to acute, drug-induced hypotension. Circulation. 1976;53(4):720–7.

Reinhard M, Lorenz L, Sommerlade L, Allignol A, Urbach H, Weiller C, et al. Impaired dynamic cerebral autoregulation in patients with cerebral amyloid angiopathy. Brain Res. 2019;1717:60–5.

Article  CAS  PubMed  Google Scholar 

Boulanger M, Schneckenburger R, Join-Lambert C, Werring DJ, Wilson D, Hodel J, et al. Diffusion-weighted imaging hyperintensities in subtypes of acute intracerebral hemorrhage. Stroke. 2018;STROKEAHA118021407.

Tsivgoulis G, Katsanos AH, Butcher KS, Boviatsis E, Triantafyllou N, Rizos I, et al. Intensive blood pressure reduction in acute intracerebral hemorrhage: a meta-analysis. Neurology. 2014;83(17):1523–9.

Article  PubMed  Google Scholar 

Kuwata N, Kuroda K, Funayama M, Sato N, Kubo N, Ogawa A. Dysautoregulation in patients with hypertensive intracerebral hemorrhage. A SPECT study. Neurosurg Rev. 1995;18(4):237–45.

Article  CAS  PubMed  Google Scholar 

Gould B, McCourt R, Asdaghi N, Dowlatshahi D, Jeerakathil T, Kate M, et al. Autoregulation of cerebral blood flow is preserved in primary intracerebral hemorrhage. Stroke. 2013;44(6):1726–8.

Article  CAS  PubMed  Google Scholar 

Powers WJ, Zazulia AR, Videen TO, Adams RE, Yundt KD, Aiyagari V, et al. Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage. Neurology. 2001;57(1):18–24.

Article  CAS  PubMed  Google Scholar 

Oeinck M, Neunhoeffer F, Buttler KJ, Meckel S, Schmidt B, Czosnyka M, et al. Dynamic cerebral autoregulation in acute intracerebral hemorrhage. Stroke. 2013;44(10):2722–8.

Article  PubMed  Google Scholar 

Reinhard M, Neunhoeffer F, Gerds TA, Niesen WD, Buttler KJ, Timmer J, et al. Secondary decline of cerebral autoregulation is associated with worse outcome after intracerebral hemorrhage. Intensive Care Med. 2010;36(2):264–71.

Article  PubMed  Google Scholar 

Ko SB, Choi HA, Parikh G, Helbok R, Schmidt JM, Lee K, et al. Multimodality monitoring for cerebral perfusion pressure optimization in comatose patients with intracerebral hemorrhage. Stroke. 2011;42(11):3087–92.

Article  PubMed  PubMed Central  Google Scholar 

Diedler J, Santos E, Poli S, Sykora M. Optimal cerebral perfusion pressure in patients with intracerebral hemorrhage: an observational case series. Crit Care Lond Engl. 2014;18(2):R51.

Article  Google Scholar 

Thomas E, Czosnyka M, Hutchinson P. Calculation of cerebral perfusion pressure in the management of traumatic brain injury: joint position statement by the councils of the Neuroanaesthesia and Critical Care Society of Great Britain and Ireland (NACCS) and the Society of British Neurological Surgeons (SBNS). Br J Anaesth. 2015;115(4):487–8.

Article  CAS  PubMed  Google Scholar 

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