Hersh AO, von Scheven E, Yazdany J, Panopalis P, Trupin L, Julian L, Katz P, Criswell LA, Yelin E (2009) Differences in long-term disease activity and treatment of adult patients with childhood-and adult-onset systemic lupus erythematosus. Arthritis Rheum 61:13–20

Article  PubMed  PubMed Central  Google Scholar 

Wenderfer SE, Chang JC, Davies AG, Luna IY, Scobell R, Sears C, Magella B, Mitsnefes M, Stotter BR, Dharnidharka VR (2022) Using a multi-institutional pediatric learning health system to identify systemic lupus erythematosus and lupus nephritis: development and validation of computable phenotypes. Clin J Am Soc Nephrol 17:65–74

Article  CAS  PubMed  PubMed Central  Google Scholar 

De Mutiis C, Wenderfer SE, Orjuela A, Bagga A, Basu B, Sar T, Aggarwal A, Jain A, Yap HK, Ito S, Ohnishi A, Iwata N, Kasapcopur O, Laurent A, Mastrangelo A, Ogura M, Shima Y, Rianthavorn P, Silva CA, Trindade V, Dormi A, Tullus K (2022) Defining renal remission in an international cohort of 248 children and adolescents with lupus nephritis. Rheumatology (Oxford) 61(6):2563–2571. https://doi.org/10.1093/rheumatology/keab746

Chan EY, Yap DY, Wong WT, Wong WH, Wong SW, Lin KY, Hui FY, Yee-Ming J, Lam SS, Wong JK, Lai FF, Ho TW, Tong PC, Lai WM, Chan TM, Ma AL (2023) Long-term outcomes of children and adolescents with biopsy-proven childhood-onset lupus nephritis. Kidney Int Rep 8:141–150. https://doi.org/10.1016/j.ekir.2022.10.014

Article  PubMed  Google Scholar 

Yap DY, Tang CS, Ma MK, Lam MF, Chan TM (2012) Survival analysis and causes of mortality in patients with lupus nephritis. Nephrol Dial Transplant 27:3248–3254

Article  PubMed  Google Scholar 

Chan EYH, Yap DYH, Wong WHS, Ho TW, Tong PC, Lai WM, Chan TM, Ma ALT (2022) Demographics and long-term outcomes of children with end-stage kidney disease: a 20-year territory-wide study. Nephrology (Carlton) 27:171–180. https://doi.org/10.1111/nep.14007

Article  CAS  PubMed  Google Scholar 

Oni L, Wright RD, Marks S, Beresford MW, Tullus K (2021) Kidney outcomes for children with lupus nephritis. Pediatr Nephrol 36:1377–1385

Article  PubMed  Google Scholar 

Rovin BH, Adler SG, Barratt J, Bridoux F, Burdge KA, Chan TM, Cook HT, Fervenza FC, Gibson KL, Glassock RJ (2021) KDIGO 2021 Clinical Practice Guideline for the management of glomerular diseases. Kidney Int Suppl 100:S1–S276

Article  Google Scholar 

Chan EYH, Ma ALT, Tullus K (2021) When should we start and stop ACEi/ARB in paediatric chronic kidney disease? Pediatr Nephrol 36:1751–1764. https://doi.org/10.1007/s00467-020-04788-w

Article  PubMed  Google Scholar 

Chan EY-h, Tullus K (2021) Rituximab in children with steroid sensitive nephrotic syndrome: in quest of the optimal regimen. Pediatr Nephrol 36:1397–1405. https://doi.org/10.1007/s00467-020-04609-0

Article  PubMed  Google Scholar 

Marlais M, Wlodkowski T, Printza N, Kronsteiner D, Krisam R, Sauer L, Aksenova M, Ashoor I, Awan A, Bacchetta J (2022) Clinical factors and adverse kidney outcomes in children with ANCA-associated glomerulonephritis. Am J Kidney Dis 81:119–122. https://doi.org/10.1053/j.ajkd.2022.05.013

Article  PubMed  Google Scholar 

Chan EY-h, Webb H, Yu E, Ghiggeri GM, Kemper MJ, Ma AL-t, Yamamura T, Sinha A, Bagga A, Hogan J (2020) Both the rituximab dose and maintenance immunosuppression in steroid-dependent/frequently-relapsing nephrotic syndrome have important effects on outcomes. Kidney Int. 97:393–401. https://doi.org/10.1016/j.kint.2019.09.033

Article  CAS  PubMed  Google Scholar 

Chan EY, Yap DY, Colucci M, Ma AL, Parekh RS, Tullus K (2022) Use of rituximab in childhood idiopathic nephrotic syndrome. Clin J Am Soc Nephrol 18:533–548. https://doi.org/10.2215/CJN.08570722

Article  Google Scholar 

Chan EY, Ellen L, Angeletti A, Arslan Z, Basu B, Boyer O, Chan C-Y, Colucci M, Dorval G, Dossier C (2022) Long-term efficacy and safety of repeated rituximab to maintain remission in idiopathic childhood nephrotic syndrome: an international study. J Am Soc Nephrol 33:1193–1207. https://doi.org/10.1681/ASN.2021111472

Article  CAS  PubMed  PubMed Central  Google Scholar 

Chan EY, Ma AL, Tullus K (2022) Hypogammaglobulinaemia following rituximab therapy in childhood nephrotic syndrome. Pediatr Nephrol 37:927–931. https://doi.org/10.1007/s00467-021-05345-9

Article  PubMed  Google Scholar 

Gilbert M, Goilav B, Hsu JJ, Nietert PJ, Meidan E, Chua A, Ardoin SP, Wenderfer SE, von Scheven E, Ruth NM, Pediatric Nephrology and Rheumatology Collaborative Group, the Childhood Arthritis and Rheumatology Research Alliance, and the American Society for Pediatric Nephrology (2021) Differences in rituximab use between pediatric rheumatologists and nephrologists for the treatment of refractory lupus nephritis and renal flare in childhood-onset SLE. Pediatr Rheumatol Online 19:137

Article  Google Scholar 

Podolskaya A, Stadermann M, Pilkington C, Marks SD, Tullus K (2008) B cell depletion therapy for 19 patients with refractory systemic lupus erythematosus. Arch Dis Child 93:401–406

Article  CAS  PubMed  Google Scholar 

Nwobi O, Abitbol CL, Chandar J, Seeherunvong W, Zilleruelo G (2008) Rituximab therapy for juvenile-onset systemic lupus erythematosus. Pediatr Nephrol 23:413–419

Article  PubMed  Google Scholar 

Hogan J, Godron A, Baudouin V, Kwon T, Harambat J, Deschênes G, Niel O (2018) Combination therapy of rituximab and mycophenolate mofetil in childhood lupus nephritis. Pediatr Nephrol 33:111–116

Article  PubMed  Google Scholar 

Basu B, Roy B, Babu BG (2017) Efficacy and safety of rituximab in comparison with common induction therapies in pediatric active lupus nephritis. Pediatr Nephrol 32:1013–1021

Article  PubMed  Google Scholar 

Watson L, Beresford M, Maynes C, Pilkington C, Marks S, Glackin Y, Tullus K (2015) The indications, efficacy and adverse events of rituximab in a large cohort of patients with juvenile-onset SLE. Lupus 24:10–17

Article  CAS  PubMed  Google Scholar 

Marks SD, Patey S, Brogan PA, Hasson N, Pilkington C, Woo P, Tullus K (2005) B lymphocyte depletion therapy in children with refractory systemic lupus erythematosus. Arthritis Rheum 52:3168–3174

Article  CAS  PubMed  Google Scholar 

Yap DY, Li PH, Tang C, So BY, Kwan LP, Chan GC, Lau CS, Chan TM (2022) Long-term results of triple immunosuppression with tacrolimus added to mycophenolate and corticosteroids in the treatment of lupus nephritis. Kidney Int Rep 7:516–525

Article  PubMed  Google Scholar 

Yap DY, Tang C, Ma MK, Mok MM, Chan GC, Kwan LP, Chan TM (2017) Longterm data on disease flares in patients with proliferative lupus nephritis in recent years. J Rheumatol 44:1375–1383

Article  CAS  PubMed  Google Scholar 

Tan EM, Cohen AS, Fries JF, Masi AT, Mcshane DJ, Rothfield NF, Schaller JG, Talal N, Winchester RJ (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 25:1271–1277

Article  CAS  PubMed  Google Scholar 

Markowitz G, D’Agati V (2007) The ISN/RPS 2003 classification of lupus nephritis: an assessment at 3 years. Kidney Int 71:491–495

Article  CAS  PubMed  Google Scholar 

Schwartz GJ, Munoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, Furth SL (2009) New equations to estimate GFR in children with CKD. J Am Soc Nephrol 20:629–637

Article  PubMed  PubMed Central  Google Scholar 

Miller WG, Kaufman HW, Levey AS, Straseski JA, Wilhelms KW, Yu H-YE, Klutts JS, Hilborne LH, Horowitz GL, Lieske J (2021) National Kidney Foundation Laboratory Engagement Working Group recommendations for implementing the CKD-EPI 2021 race-free equations for estimated glomerular filtration rate: practical guidance for clinical laboratories. Clin Chem 68:511–520. https://doi.org/10.1093/clinchem/hvab278

Article  Google Scholar 

Aragon E, Resontoc L, Chan Y, Lau Y, Tan P, Loh H, Ng K, Yap H (2016) Long-term outcomes with multi-targeted immunosuppressive protocol in children with severe proliferative lupus nephritis. Lupus 25:399–406

Article  CAS  PubMed  Google Scholar 

Yap DY, Lai KN (2015) Pathogenesis of renal disease in systemic lupus erythematosus–the role of autoantibodies and lymphocytes subset abnormalities. Int J Mol Sci 16:7917–7931

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rovin BH, Furie R, Latinis K, Looney RJ, Fervenza FC, Sanchez-Guerrero J, Maciuca R, Zhang D, Garg JP, Brunetta P (2012) Efficacy and safety of rituximab in patients with active proliferative lupus nephritis: the lupus nephritis assessment with rituximab study. Arthritis Rheum 64:1215–1226

Article  CAS  PubMed  Google Scholar 

Demir S, Gülhan B, Özen S, Çeleğen K, Batu ED, Taş N, Orhan D, Bilginer Y, Düzova A, Ozaltin F (2021) Long-term renal survival of paediatric patients with lupus nephritis. Nephrol Dial Transplant 37:1069–1077. https://doi.org/10.1093/ndt/gfab152

Article  CAS  Google Scholar 

Qiu S, Zhang H, Yu S, Yang Q, Zhang G, Yang H, Li Q, Wang M (2021) Clinical manifestations, prognosis, and treat-to-target assessment of pediatric lupus nephritis. Pediatr Nephrol 37:367–376. https://doi.org/10.1007/s00467-021-05164-y

Article  PubMed  PubMed Central  Google Scholar 

Chan T, Tse K, Tang CS, Lai K, Li F (2005) Long-term outcome of patients with diffuse proliferative lupus nephritis treated with prednisolone and oral cyclophosphamide followed by azathioprine. Lupus 14:265–272

Article  CAS  PubMed  Google Scholar 

Chan EY, Liu MS, Or PC, Ma AL (2022) Outcomes and perception of cloud-based remote patient monitoring in children receiving automated peritoneal dialysis: a prospective study. Pediatr Nephrol 38:2171–2178. https://doi.org/10.1007/s00467-022-05828-3

Hari P, Bagga A, Mahajan P, Dinda A (2009) Outcome of lupus nephritis in Indian children. Lupus 18:348–354

Article  CAS  PubMed  Google Scholar 

Wong S-N, Tse K-C, Lee T-L, Lee K-W, Chim S, Lee K-P, Wai-Po Chu R, Chan W, Fong K-W, Hui J (2006) Lupus nephritis in Chinese children–a territory-wide cohort study in Hong Kong. Pediatr Nephrol 21:1104–1112

Article