Behl T, Kaur D, Sehgal A, Singh S, Sharma N, Zengin G, Andronie-Cioara FL, Toma MM, Bungau S, Bumbu AG (2021) Role of monoamine oxidase activity in Alzheimer’s disease: an insight into the therapeutic potential of inhibitors. Molecules 26(12):3724
Article CAS PubMed PubMed Central Google Scholar
Mubangizi V, Maling S, Obua C, Tsai AC (2020) Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study. BMC Geriatr 20(1):1–7
Ojagbemi A, Okekunle AP, Babatunde O (2021) Dominant and modifiable risk factors for dementia in sub-Saharan Africa: a systematic review and meta-analysis. Front Neurol 12:627761
Article PubMed PubMed Central Google Scholar
Li X, Feng X, Sun X, Hou N, Han F, Liu Y (2022) Global, regional, and national burden of Alzheimer’s disease and other dementias, 1990–2019. Front Aging Neurosci 14:937486
Article PubMed PubMed Central Google Scholar
Bozoki A, Giordani B, Heidebrink JL, Berent S, Foster NL (2001) Mild cognitive impairments predict dementia in nondemented elderly patients with memory loss. Arch Neurol 58(3):411–416
Article CAS PubMed Google Scholar
Nichols E, Steinmetz JD, Vollset SE, Fukutaki K, Chalek J, Abd-Allah F, Abdoli A, Abualhasan A, Abu-Gharbieh E, Akram TT (2022) Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019. Lancet Public Health 7(2):e105–e125
Bar-Am O, Amit T, Kupershmidt L, Aluf Y, Mechlovich D, Kabha H, Danovitch L, Zurawski VR, Youdim MB, Weinreb O (2015) Neuroprotective and neurorestorative activities of a novel iron chelator-brain selective monoamine oxidase-A/monoamine oxidase-B inhibitor in animal models of Parkinson’s disease and aging. Neurobiol Aging 36(3):1529–1542
Article CAS PubMed Google Scholar
Hampel H, Mesulam M-M, Cuello AC, Farlow MR, Giacobini E, Grossberg GT, Khachaturian AS, Vergallo A, Cavedo E, Snyder PJ (2018) The cholinergic system in the pathophysiology and treatment of Alzheimer’s disease. Brain 141(7):1917–1933
Article PubMed PubMed Central Google Scholar
Humpel C (2011) Chronic mild cerebrovascular dysfunction as a cause for Alzheimer’s disease? Exp Gerontol 46(4):225–232
Article CAS PubMed PubMed Central Google Scholar
Klafki H-W, Staufenbiel M, Kornhuber J, Wiltfang J (2006) Therapeutic approaches to Alzheimer’s disease. Brain 129(11):2840–2855
Jellinger KA, Korczyn AD (2018) Are dementia with Lewy bodies and Parkinson’s disease dementia the same disease? BMC Med 16(1):1–16
Surmeier DJ (2018) Determinants of dopaminergic neuron loss in Parkinson’s disease. FEBS J 285(19):3657–3668
Article CAS PubMed PubMed Central Google Scholar
Bellucci A, Navarria L, Zaltieri M, Falarti E, Bodei S, Sigala S, Battistin L, Spillantini M, Missale C, Spano P (2011) Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson’s disease. J Neurochem 116(4):588–605
Article CAS PubMed Google Scholar
Hampel H, Lista S, Vanmechelen E, Zetterberg H, Giorgi FS, Galgani A, Blennow K, Caraci F, Das B, Yan R (2020) β-Secretase1 biological markers for Alzheimer’s disease: state-of-art of validation and qualification. Alzheimer’s Res Ther 12(1):1–14
Hampel H, Vassar R, De Strooper B, Hardy J, Willem M, Singh N, Zhou J, Yan R, Vanmechelen E, De Vos A (2021) The β-secretase BACE1 in Alzheimer’s disease. Biol Psychiat 89(8):745–756
Article CAS PubMed Google Scholar
Carocci A, Catalano A, Sinicropi MS, Genchi G (2018) Oxidative stress and neurodegeneration: the involvement of iron. Biometals 31(5):715–735
Article CAS PubMed Google Scholar
Ramli NZ, Yahaya MF, Tooyama I, Damanhuri HA (2020) A mechanistic evaluation of antioxidant nutraceuticals on their potential against age-associated neurodegenerative diseases. Antioxidants 9(10):1019
Article CAS PubMed PubMed Central Google Scholar
Ward RJ, Dexter DT, Crichton RR (2012) Chelating agents for neurodegenerative diseases. Curr Med Chem 19(17):2760–2772
Article CAS PubMed Google Scholar
D’Onofrio G, Nabavi SM, Sancarlo D, Greco A, Pieretti S (2021) Crocus sativus L. (Saffron) in Alzheimer’s disease treatment: bioactive effects on cognitive impairment. Curr Neuropharmacol 19(9):1606
Article PubMed PubMed Central Google Scholar
Hannan MA, Rahman MA, Sohag AAM, Uddin MJ, Dash R, Sikder MH, Rahman MS, Timalsina B, Munni YA, Sarker PP (2021) Black cumin (Nigella sativa L.): a comprehensive review on phytochemistry, health benefits, molecular pharmacology, and safety. Nutrients 13(6):1784
Article PubMed PubMed Central Google Scholar
Mima Y, Izumo N, Chen J-R, Yang S-C, Furukawa M, Watanabe Y (2020) Effects of Coriandrum sativum seed extract on aging-induced memory impairment in Samp8 mice. Nutrients 12(2):455
Article CAS PubMed PubMed Central Google Scholar
Aloni PD, Nayak AR, Chaurasia SR, Deopujari JY, Chourasia C, Purohit HJ, Taori GM, Daginawala HF, Kashyap RS (2016) Effect of Fagonia arabica on thrombin induced release of t-PA and complex of PAI-1 tPA in cultured HUVE cells. J Tradit Complement Med 6(3):219–223
Patil SM, Ramu R, Shirahatti PS, Shivamallu C, Amachawadi RG (2021) A systematic review on ethnopharmacology, phytochemistry and pharmacological aspects of Thymus vulgaris Linn. Heliyon 7(5):e07054
Article CAS PubMed PubMed Central Google Scholar
Eskandari-Roozbahani N, Shomali T, Taherianfard M (2019) Neuroprotective effect of Zataria multiflora essential oil on rats with Alzheimer disease: a mechanistic study. Basic Clin Neurosci 10(1):85
CAS PubMed PubMed Central Google Scholar
Ojo OA, Okesola MA, Ekakitie LI, Ajiboye BO, Oyinloye BE, Agboinghale PE, Onikanni AS (2020) Gongronema latifolium Benth. leaf extract attenuates diabetes-induced neuropathy via inhibition of cognitive, oxidative stress and inflammatory response. J Sci Food Agric 100(12):4504–4511
Article CAS PubMed Google Scholar
Ogunyemi OM, Gyebi GA, Ibrahim IM, Esan AM, Olaiya CO, Soliman MM, Batiha GE-S (2022) Identification of promising multi-targeting inhibitors of obesity from Vernonia amygdalina through computational analysis. Mol Divers 27:1–25
Ojo OA, Ojo AB, Okolie C, Nwakama M-AC, Iyobhebhe M, Evbuomwan IO, Nwonuma CO, Maimako RF, Adegboyega AE, Taiwo OA (2021) Deciphering the interactions of bioactive compounds in selected traditional medicinal plants against Alzheimer’s diseases via pharmacophore modeling, auto-QSAR, and molecular docking approaches. Molecules 26(7):1996
Article CAS PubMed PubMed Central Google Scholar
Oyinloye BE, Iwaloye O, Ajiboye BO (2021) Polypharmacology of Gongronema latifolium leaf secondary metabolites against protein kinases implicated in Parkinson’s disease and Alzheimer’s disease. Sci Afr 12:e00826
Morebise O, Fafunso MA, Makinde JM, Olajide OA, Awe E (2002) Antiinflammatory property of the leaves of Gongronema latifolium. Phytother Res 16(S1):75–77
Nwanna E, Oyeleye S, Ogunsuyi O, Oboh G, Boligon A, Athayde M (2016) In vitro neuroprotective properties of some commonly consumed green leafy vegetables in Southern Nigeria. NFS J 2:19–24
Ogundipe O, Moody J, Akinyemi T, Raman A (2003) Hypoglycemic potentials of methanolic extracts of selected plant foods in alloxanized mice. Plant Foods Hum Nutr 58(3):1–7
Harbone J (1980) Phytochemical analysis: a guide to modern techniques of plant analysis. Chapman & Hall, New York
Gyebi GA, Adebayo JO, Olorundare OE, Pardede A, Ninomiya M, Saheed AO, Babatunde AS, Koketsu M (2018) Iloneoside: a cytotoxic ditigloylated pregnane glycoside from the leaves of Gongronema latifolium Benth. Nat Prod Res 32(24):2882–2886
Article CAS PubMed Google Scholar
Ellman GL, Courtney KD, Andres V Jr, Featherstone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7(2):88–95
Article CAS PubMed Google Scholar
Perry NS, Houghton PJ, Theobald A, Jenner P, Perry EK (2000) In-vitro inhibition of human erythrocyte acetylcholinesterase by Salvia lavandulaefolia essential oil and constituent terpenes. J Pharm Pharmacol 52(7):895–902
Article CAS PubMed Google Scholar
Turski W, Turska E, Gross-Bellard M (1972) Modification of the spectrophotometric method of the determination of monoamine oxidase. Enzyme 14:211–220
Green A, Haughton TM (1961) A colorimetric method for the estimation of monoamine oxidase. Biochem J 78(1):172–175
Comments (0)