Vande Walle L, Lamkanfi M. Pyroptosis. Curr Biol. 2016;26(13):R568–72. https://doi.org/10.1016/j.cub.2016.02.019.
Shi J, Gao W, Shao F. Pyroptosis: gasdermin-mediated programmed necrotic cell death. Trends Biochem Sci. 2017;42(4):245–54. https://doi.org/10.1016/j.tibs.2016.10.004.
Article CAS PubMed Google Scholar
Liu Z, Wang C, Lin C. Pyroptosis as a double-edged sword: The pathogenic and therapeutic roles in inflammatory diseases and cancers. Life Sci. 2023;318:121498. https://doi.org/10.1016/j.lfs.2023.121498.
Article CAS PubMed Google Scholar
Kong X, Zhao Y, Wang X, et al. Loganin reduces diabetic kidney injury by inhibiting the activation of NLRP3 inflammasome-mediated pyroptosis. Chem Biol Interact. 2023;382:110640. https://doi.org/10.1016/j.cbi.2023.110640.
Article CAS PubMed Google Scholar
Zhang X, Wang Q, Cao G, Luo M, Hou H, Yue C. Pyroptosis by NLRP3/caspase-1/gasdermin-D pathway in synovial tissues of rheumatoid arthritis patients. J Cell Mol Med. 2023. https://doi.org/10.1111/jcmm.17834.10.1111/jcmm.17834.
Article PubMed PubMed Central Google Scholar
Yu P, Zhang X, Liu N, Tang L, Peng C, Chen X. Pyroptosis: mechanisms and diseases. Signal Transduct Target Ther. 2021;6(1):128–35. https://doi.org/10.1038/s41392-021-00507-5.
Article PubMed PubMed Central Google Scholar
Coll RC, Schroder K, Pelegrín P. NLRP3 and pyroptosis blockers for treating inflammatory diseases. Trends Pharmacol Sci. 2022;43(8):653–68. https://doi.org/10.1016/j.tips.2022.04.003.
Article CAS PubMed Google Scholar
Zhou J, Qiu J, Song Y, et al. Pyroptosis and degenerative diseases of the elderly. Cell Death Dis. 2023;14(2):94–101. https://doi.org/10.1038/s41419-023-05634-1.
Article PubMed PubMed Central Google Scholar
Chi H, Chang HY, Sang TK. Neuronal cell death mechanisms in major neurodegenerative diseases. Int J Mol Sci. 2018;19(10):3082–90. https://doi.org/10.3390/ijms19103082.
Article CAS PubMed PubMed Central Google Scholar
Elliott EI, Sutterwala FS. Initiation and perpetuation of NLRP3 inflammasome activation and assembly. Immunol Rev. 2015;265(1):35–52. https://doi.org/10.1111/imr.12286.
Article CAS PubMed PubMed Central Google Scholar
Holbrook JA, Jarosz-Griffiths HH, Caseley E, et al. Neurodegenerative disease and the NLRP3 inflammasome. Front Pharmacol. 2021;12:643254. https://doi.org/10.3389/fphar.2021.643254.
Article CAS PubMed PubMed Central Google Scholar
Paik S, Kim JK, Silwal P, Sasakawa C, Jo EK. An update on the regulatory mechanisms of NLRP3 inflammasome activation. Cell Mol Immunol. 2021;18(5):1141–60. https://doi.org/10.1038/s41423-021-00670-3.
Article CAS PubMed PubMed Central Google Scholar
Kelley N, Jeltema D, Duan Y, He Y. The NLRP3 inflammasome: an overview of mechanisms of activation and regulation. Int J Mol Sci. 2019;20(13):3328–36. https://doi.org/10.3390/ijms20133328.
Article CAS PubMed PubMed Central Google Scholar
Akbal A, Dernst A, Lovotti M, Mangan MSJ, McManus RM, Latz E. How location and cellular signaling combine to activate the NLRP3 inflammasome. Cell Mol Immunol. 2022;19(11):1201–14. https://doi.org/10.1038/s41423-022-00922-w.
Article CAS PubMed PubMed Central Google Scholar
Tartey S, Kanneganti TD. Inflammasomes in the pathophysiology of autoinflammatory syndromes. J Leukoc Biol. 2020;107(3):379–91. https://doi.org/10.1002/JLB.3MIR0919-191R.
Article CAS PubMed Google Scholar
Knierim JJ. The hippocampus. Curr Biol. 2015;25(23):R1116–21. https://doi.org/10.1016/j.cub.2015.10.049.
Article CAS PubMed Google Scholar
Moonen S, Koper MJ, Van Schoor E, et al. Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons. Acta Neuropathol. 2023;145(2):175–95. https://doi.org/10.1007/s00401-022-02528-y.
Article CAS PubMed Google Scholar
Leng F, Edison P. Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here? Nat Rev Neurol. 2021;17(3):157–72. https://doi.org/10.1038/s41582-020-00435-y.
Heidari A, Yazdanpanah N, Rezaei N. The role of Toll-like receptors and neuroinflammation in Parkinson’s disease. J Neuroinflammation. 2022;19(1):135–46. https://doi.org/10.1186/s12974-022-02496-w.
Article CAS PubMed PubMed Central Google Scholar
Li J, Hao JH, Yao D, et al. Caspase-1 inhibition prevents neuronal death by targeting the canonical inflammasome pathway of pyroptosis in a murine model of cerebral ischemia. CNS Neurosci Ther. 2020;26(9):925–39. https://doi.org/10.1111/cns.13384.
Article CAS PubMed PubMed Central Google Scholar
Tuo QZ, Zhang ST, Lei P. Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications. Med Res Rev. 2022;42(1):259–305. https://doi.org/10.1002/med.21817.
Gonçalves J, Baptista S, Martins T, et al. Methamphetamine-induced neuroinflammation and neuronal dysfunction in the mice hippocampus: preventive effect of indomethacin. Eur J Neurosci. 2010;31(2):315–26. https://doi.org/10.1111/j.1460-9568.2009.07059.x.
Han C, Yang Y, Guan Q, et al. New mechanism of nerve injury in Alzheimer’s disease: β-amyloid-induced neuronal pyroptosis. J Cell Mol Med. 2020;24(14):8078–90. https://doi.org/10.1111/jcmm.15439.
Article CAS PubMed PubMed Central Google Scholar
Yang J, Gao J, Han D, et al. Hippocampal changes in inflammasomes, apoptosis, and MEMRI after radiation-induced brain injury in juvenile rats. Radiat Oncol. 2020;15(1):78–90. https://doi.org/10.1186/s13014-020-01525-3.
Article CAS PubMed PubMed Central Google Scholar
Dugger BN, Dickson DW. Pathology of neurodegenerative diseases. Cold Spring Harb Perspect Biol. 2017;9(7):028–35. https://doi.org/10.1101/cshperspect.a028035.
Malani Shukla N, Lotze TE, Muscal E. Inflammatory diseases of the central nervous system. Neurol Clin. 2021;39(3):811–28. https://doi.org/10.1016/j.ncl.2021.04.004.
Subhramanyam CS, Wang C, Hu Q, Dheen ST. Microglia-mediated neuroinflammation in neurodegenerative diseases. Semin Cell Dev Biol. 2019;94:112–20. https://doi.org/10.1016/j.semcdb.2019.05.004.
Article CAS PubMed Google Scholar
Morley JE. An overview of cognitive impairment. Clin Geriatr Med. 2018;34(4):505–13. https://doi.org/10.1016/j.cger.2018.06.003.
Pei H, Ma L, Cao Y, et al. Traditional Chinese medicine for Alzheimer’s disease and other cognitive impairment: a review. Am J Chin Med. 2020;48(3):487–511. https://doi.org/10.1142/S0192415X20500251.
Article CAS PubMed Google Scholar
Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer’s disease: recent advances. Mol Neurodegener. 2020;15(1):30–41. https://doi.org/10.1186/s13024-020-00376-6.
Article PubMed PubMed Central Google Scholar
Terreros-Roncal J, Moreno-Jiménez EP, Flor-García M, et al. Impact of neurodegenerative diseases on human adult hippocampal neurogenesis. Science. 2021;374(6571):1106–13. https://doi.org/10.1126/science.abl5163.
Article CAS PubMed PubMed Central Google Scholar
LaFerla FM, Hall CK, Ngo L, Jay G. Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice. J Clin Invest. 1996;98(7):1626–32. https://doi.org/10.1172/JCI118957.
Article CAS PubMed PubMed Central Google Scholar
Liy PM, Puzi NNA, Jose S, Vidyadaran S. Nitric oxide modulation in neuroinflammation and the role of mesenchymal stem cells. Exp Biol Med (Maywood). 2021;246(22):2399–406. https://doi.org/10.1177/1535370221997052.
Article CAS PubMed Google Scholar
Teleanu DM, Niculescu AG, Lungu II, et al. An overview of oxidat
Comments (0)