Acharjee S, Noorbakhsh F, Stemkowski PL, Olechowski C, Cohen EA, Ballanyi K et al (2010) HIV-1 viral protein R causes peripheral nervous system injury associated with in vivo neuropathic pain. FASEB J 24(11):4343–4353. https://doi.org/10.1096/fj.10-162313
Article CAS PubMed Google Scholar
Affandi JS, Price P, Imran D, Yunihastuti E, Djauzi S, Cherry CL (2008) Can we predict neuropathy risk before stavudine prescription in a resource-limited setting? AIDS Res Hum Retroviruses 24(10):1281–1284. https://doi.org/10.1089/aid.2008.0045
Article CAS PubMed Google Scholar
Alghamdi J, Padmanabhan S (2014) Fundamentals of complex trait genetics and association studies. Handbook of pharmacogenomics and stratified medicine. Amsterdam (NL): Elsevier 242–243. https://doi.org/10.1016/B978-0-12-386882-4.00012-8
Apostolova N, Blas-García A, Esplugues JV (2011) Mitochondrial interference by anti-HIV drugs: mechanisms beyond Pol-γ inhibition. Trends Pharmacol Sci 32(12):715–725. https://doi.org/10.1016/j.tips.2011.07.007
Article CAS PubMed Google Scholar
Bursac Z, Gauss CH, Williams DK, Hosmer DW (2008) Purposeful selection of variables in logistic regression. Source Code Biol Med 3:17. https://doi.org/10.1186/1751-0473-3-17
Article PubMed PubMed Central Google Scholar
Cao L, Butler MB, Tan L, Draleau KS, Koh WY (2012) Murine immunodeficiency virus-induced peripheral neuropathy and the associated cytokine responses. J Immunol 189(7):3724–3733
Article CAS PubMed Google Scholar
Cavalli G, Colafrancesco S, Emmi G, Imazio M, Lopalco G, Maggio MC et al (2021) Interleukin 1α: a comprehensive review on the role of IL-1α in the pathogenesis and treatment of autoimmune and inflammatory diseases. Autoimmun Rev 20(3):102763. https://doi.org/10.1016/j.autrev.2021.102763
Cavounidis J (2018) The migration experience of Greece and the impact of the economic crisis on its migrant and native populations. Eur J Pub Health 28(5):20–23. https://doi.org/10.1093/eurpub/cky204
Cherry CL, Rosenow A, Affandi JS, McArthur JC, Wesselingh SL, Price P (2008) Cytokine genotype suggests a role for inflammation in nucleoside analog-associated sensory neuropathy (NRTI-SN) and predicts an individual’s NRTI-SN risk. AIDS Res Hum Retroviruses 24(2):117–123
Article CAS PubMed Google Scholar
Cherry CL, Wesselingh SL, Lal L, McArthur JC (2005) Evaluation of a clinical screening tool for HIV-associated sensory neuropathies. Neurology 65(11):1778–1781
Chew CS, Cherry CL, Imran D, Yunihastuti E, Kamarulzaman A, Varna S et al (2011a) Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients. Tissue Antigens 77(2):126–130
Article CAS PubMed Google Scholar
Chew CS, Cherry CL, Kamarulzaman A, Yien TH, Aghafar Z, Price P (2011b) A longitudinal study of the effects of ART on plasma chemokine levels in Malaysian HIV patients. Dis Markers 14:303–309. https://doi.org/10.1155/2011/714057
Chien CY, Tai SY, Li KH, Yang HL, Chan LP, Hsi E, Wang LF, Ho KY, Chang NC (2021) The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with sudden sensorineural hearing loss in a Taiwanese population: a case control study. J Otolaryngol Head Neck Surg = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale 50(1):69. https://doi.org/10.1186/s40463-021-00550-w
Ciccosanti F, Corazzari M, Soldani F, Matarrese P, Pagliarini V, Iadevaia V et al (2010) Proteomic analysis identifies prohibitin down-regulation as a crucial event in the mitochondrial damage observed in HIV-infected patients. Antivir Ther 15(3):377–390. https://doi.org/10.3851/IMP1530
Article CAS PubMed Google Scholar
Clark AK, Old EA, Malcangio M (2013) Neuropathic pain and cytokines: current perspectives. J Pain Res 6:803–814
PubMed PubMed Central Google Scholar
Corley PA (2000) Interleukin-1 receptor antagonist as a treatment of HIV infection. Med Hypotheses 54(4):513–518. https://doi.org/10.1054/mehy.1998.0817
Article CAS PubMed Google Scholar
Costarelli S, Torti C, Gatta LB, Tinelli C, Lapadula G, Quiros-Roldan E et al (1999) (2007) No evidence of relation between peripheral neuropathy and presence of hemochromatosis gene mutations in HIV-1-positive patients. J Acquir Immune Defic Syndr 46(2):255–256. https://doi.org/10.1097/QAI.0b013e3180ed44d9
Della-Flora Nunes G, Wilson ER, Marziali LN, Hurley E, Silvestri N, He B et al (2021) Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells. Nat Commun 12(1):3285. https://doi.org/10.1038/s41467-021-23552-8
Article CAS PubMed PubMed Central Google Scholar
Dominici R, Cattaneo M, Malferrari G, Archi D, Mariani C, Grimaldi LM, Biunno I (2002) Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha. Immunogenetics 54(2):82–86. https://doi.org/10.1007/s00251-002-0445-9
Article CAS PubMed Google Scholar
Dutra WO, Moreira PR, Souza PE, Gollob KJ, Gomez RS (2009) Implications of cytokine gene polymorphisms on the orchestration of the immune response: lessons learned from oral diseases. Cytokine Growth Factor Rev 20(3):223–232. https://doi.org/10.1016/j.cytogfr.2009.05.005
Article CAS PubMed Google Scholar
Feng X, Liu J (2020) Association between IL-1A (-889C/T) polymorphism and susceptibility of chronic periodontitis: a meta-analysis. Gene 729:144227. https://doi.org/10.1016/j.gene.2019.144227
Fields JA, Swinton MK, Carson A, Soontornniyomkij B, Lindsay C, Han MM et al (2019) Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice. Sci Rep 9(1):17158. https://doi.org/10.1038/s41598-019-53466-x
Article CAS PubMed PubMed Central Google Scholar
Frank SA (2002) Immunology and evolution of infectious disease. Chapter 8, Genetic variability of hosts. Princeton (NJ): Princeton University Press. Available from: https://www.ncbi.nlm.nih.gov/books/NBK2401/
Harsini S, Ziaee V, Tahghighi F, Mahmoudi M, Rezaei A, Soltani S et al (2016) Association of interleukin-2 and interferon-γ single nucleotide polymorphisms with Juvenile systemic lupus erythematosus. Allergol Immunopathol 44(5):422–426. https://doi.org/10.1016/j.aller.2015.12.005
Hershey GK, Friedrich MF, Esswein LA, Thomas ML, Chatila TA (1997) The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor. N Engl J Med 337(24):1720–1725. https://doi.org/10.1056/NEJM199712113372403
Article CAS PubMed Google Scholar
Jazebi N, Evans C, Kadaru HS, Kompella D, Raji M, Fang F et al (2021) HIV-related neuropathy: pathophysiology, treatment and challenges. J Neurol Exp Neurosci 7(1):15–24. https://doi.org/10.17756/jnen.2021-082
Article PubMed PubMed Central Google Scholar
Invitrogen (2023) Cytokine genotyping kit worksheet. Code no.: 7892010. Available at: https://kanidis.gr/wp-content/uploads/Cytokines-Genotyping.pdf
Ioannidis JP, Trikalinos TA, Ioannidis KMJ, J, (2006) Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am J Epidemiol 164(7):609–614. https://doi.org/10.1093/aje/kwj259
Jarvik GP, Wang X, Fontanillas P, Kim E, Chanprasert S, Gordon AS et al (2020) Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis. HGG Advances 1(1):100010. https://doi.org/10.1016/j.xhgg.2020.100010
Kallianpur AR, Hulgan T, Canter JA, Ritchie MD, Haines JL, Robbins GK et al (2006) Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy. AIDS (london, England) 20(11):1503–1513. https://doi.org/10.1097/01.aids.0000237366.56864.3c
Article CAS PubMed Google Scholar
Kallianpur AR, Gerschenson M, Hulgan T, Kaur H, Clifford DB, Haas DW et al (2018) Hemochromatosis (HFE) gene variants are associated with increased mitochondrial DNA levels during HIV-1 infection and antiretroviral therapy. AIDS Res Hum Retroviruses 34(11):942–949. https://doi.org/10.1089/AID.2018.0025
Article CAS PubMed PubMed Central Google Scholar
Kallianpur AR, Wen W, Erwin AL, Clifford DB, Hulgan T, Robbins GK (2020) Higher iron stores and the HFE 187C>G variant delay onset of peripheral neuropathy during combination antiretroviral therapy. PloS one 15(10):e0239758. https://doi.org/10.1371/journal.pone.0239758
Kamerman PR, Moss PJ, Weber J, Wallace VC, Rice AS, Huang W (2012) Pathogenesis of HIV-associated sensory neuropathy: evidence from in vivo and in vitro experimental models. J Peripher Nerv Syst 17(1):19–31
Article CAS PubMed Google Scholar
Kenney MC, Chwa M, Atilano SR, Falatoonzadeh P, Ramirez C, Malik D et al (2014) Molecular and bioenergetic differences between cells with African versus European inherited mitochondrial DNA haplogroups: implications for population susceptibility to diseases. Biochem Biophys Acta 1842(2):208–219. https://doi.org/10.1016/j.bbadis.2013.10.016
Khalilzadeh O, Anvari M, Momen-Heravi F, Esteghamati A, Rashidi A, Mahmoudi M et al (2010) Gene polymorphisms of interleukin-4, interleukin-10 and transforming growth factor-beta in Graves’ disease. Clin Exp Med 10(2):123–128. https://doi.org/10.1007/s10238-009-0078-5
Article CAS PubMed Google Scholar
Kim HY (2017) Statistical notes for clinical researchers: chi-squared test and Fisher’s exact test. Restorative Dentistry & Endodontics 42(2):152–155. https://doi.org/10.5395/rde.2017.42.2.152
Kohler JJ, Lewis W (2007) A brief overview of mechanisms of mitochondrial toxicity from NRTIs. Environ Mol Mutagen 48(3–4):166–172. https://doi.org/10.1002/em.20223
Article CAS PubMed Google Scholar
Lingeswaran M, Goyal T, Ghosh R, Suri S, Mitra P, Misra S, Sharma P (2020) Inflammation, immunity and immunogenetics in COVID-19: a narrative review. Indian Journal of Clinical Biochemistry: IJCB 35(3):260–273. https://doi.org/10.1007/s12291-020-00897-3
Article CAS PubMed PubMed Central Google Scholar
Lu HJ, Fu YY, Wei QQ, Zhang ZJ (2021) Neuroinflammation in HIV-related neuropathic pain. Front Pharmacol 12:653852. https://doi.org/10.3389/fphar.2021.653852
Mandal RK, Wahid M, Jawed A, Dar SA, Panda AK, Akhter N, Lohani M, Mishra BN, Khan S, Areeshi MY, Haque S (2019) A trial sequential meta-analysis of IFN-γ +874 A>T (rs2430561) gene polymorphism and extrapulmonary tuberculosis risk. Microb Pathog 130:1–9. https://doi.org/10.1016/j.micpath.2018.12.050
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