Bray, F. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J. Clin. 68, 394–424 (2018).

Article  PubMed  Google Scholar 

Babjuk, M. et al. European Association of Urology Guidelines on non-muscle-invasive bladder cancer (Ta, T1, and carcinoma in situ). Eur. Urol. https://doi.org/10.1016/j.eururo.2021.08.010 (2021).

Article  PubMed  Google Scholar 

Witjes, J. A. et al. European Association of Urology Guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2020 guidelines. Eur. Urol. 79, 82–104 (2021).

Article  CAS  PubMed  Google Scholar 

Sylvester, R. J. et al. European Association of Urology (EAU) Prognostic Factor Risk Groups for non-muscle-invasive bladder cancer (NMIBC) incorporating the WHO 2004/2016 and WHO 1973 classification systems for grade: an update from the EAU NMIBC guidelines panel. Eur. Urol. 79, 480–488 (2021).

Article  PubMed  Google Scholar 

Herbert, A. et al. Population trends in emergency cancer diagnoses: the role of changing patient case-mix. Cancer Epidemiol. 63, 101574 (2019).

Article  CAS  PubMed  PubMed Central  Google Scholar 

Teoh, J. Y. et al. Global trends of bladder cancer incidence and mortality, and their associations with tobacco use and gross domestic product per capita. Eur. Urol. 78, 893–906 (2020).

Article  PubMed  Google Scholar 

Cumberbatch, M. G. K. et al. Epidemiology of bladder cancer: a systematic review and contemporary update of risk factors in 2018. Eur. Urol. 74, 784–795 (2018).

Article  PubMed  Google Scholar 

Bryan, R. T. et al. A comparison of patient and tumour characteristics in two UK bladder cancer cohorts separated by 20 years. BJU Int. 112, 169–175 (2013).

Article  PubMed  Google Scholar 

Richters, A. et al. Bladder cancer survival: women only fare worse in the first two years after diagnosis. Urol. Oncol. 37, 853–861 (2019).

Article  CAS  PubMed  Google Scholar 

Freedman, N. D., Silverman, D. T., Hollenbeck, A. R., Schatzkin, A. & Abnet, C. C. Association between smoking and risk of bladder cancer among men and women. J. Am. Med. Assoc. 306, 737–745 (2011).

Article  CAS  Google Scholar 

Uhlig, A. et al. Gender specific differences in disease-free, cancer specific and overall survival after radical cystectomy for bladder cancer: a systematic review and meta-analysis. J. Urol. 200, 48–60 (2018).

Article  PubMed  Google Scholar 

Wang, S. C. et al. The gender difference and mortality-to-incidence ratio relate to health care disparities in bladder cancer: national estimates from 33 countries. Sci. Rep. 7, 4360 (2017).

Article  PubMed  PubMed Central  Google Scholar 

Mungan, N. A. et al. Gender differences in stage-adjusted bladder cancer survival. Urology 55, 876–880 (2000).

Article  CAS  PubMed  Google Scholar 

Kluth, L. A. et al. Gender-specific differences in clinicopathologic outcomes following radical cystectomy: an international multi-institutional study of more than 8000 patients. Eur. Urol. 66, 913–919 (2014).

Article  PubMed  Google Scholar 

Liu, S. et al. The impact of female gender on bladder cancer-specific death risk after radical cystectomy: a meta-analysis of 27,912 patients. Int. Urol. Nephrol. 47, 951–958 (2015).

Article  CAS  PubMed  Google Scholar 

Mossanen, M. & Gore, J. L. The burden of bladder cancer care: direct and indirect costs. Curr. Opin. Urol. 24, 487–491 (2014).

Article  PubMed  Google Scholar 

NHS Digital. Cancer Survival in England, cancers diagnosed 2015 to 2019, followed up to 2020. NHS Digital https://digital.nhs.uk/data-and-information/publications/statistical/cancer-survival-in-england/cancers-diagnosed-2015-to-2019-followed-up-to-2020#resources (2022).

Catto, J. W. F. et al. Diagnosis, treatment and survival from bladder, upper urinary tract, and urethral cancers: real-world findings from NHS England between 2013 and 2019. BJU Int. https://doi.org/10.1111/bju.15970 (2023).

Article  PubMed  Google Scholar 

Theodorescu, D., Li, Z. & Li, X. Sex differences in bladder cancer: emerging data and call to action. Nat. Rev. Urol. 19, 447–449 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Sadighian, M. & Porten, S. Gender differences in oncologic and functional outcomes in patients with bladder cancer undergoing radical cystectomy with urinary diversion. Curr. Opin. Urol. 29, 542–547 (2019).

Article  PubMed  Google Scholar 

Burge, F. & Kockelbergh, R. Closing the gender gap: can we improve bladder cancer survival in women? - A systematic review of diagnosis, treatment and outcomes. Urol. Int. 97, 373–379 (2016).

Article  PubMed  Google Scholar 

Koti, M. et al. Sex differences in bladder cancer immunobiology and outcomes: a collaborative review with implications for treatment. Eur. Urol. Oncol. 3, 622–630 (2020).

Article  PubMed  Google Scholar 

Shu, T. D. et al. Disparities in cause-specific mortality by race and sex among bladder cancer patients from the SEER database. Cancer Causes Control https://doi.org/10.1007/s10552-023-01679-x (2023).

Article  PubMed  Google Scholar 

Dong, M. et al. Sex differences in cancer incidence and survival: a pan-cancer analysis. Cancer Epidemiol. Biomark. Prev. 29, 1389–1397 (2020).

Article  Google Scholar 

Marcos-Gragera, R. et al. Urinary tract cancer survival in Europe 1999–2007: results of the population-based study EUROCARE-5. Eur. J. Cancer https://doi.org/10.1016/j.ejca.2015.07.028 (2015).

Article  PubMed  Google Scholar 

Richters, A., Leliveld, A. M., Goossens-Laan, C. A., Aben, K. K. H. & Ozdemir, B. C. Sex differences in treatment patterns for non-advanced muscle-invasive bladder cancer: a descriptive analysis of 3484 patients of the Netherlands Cancer Registry. World J. Urol. 40, 2275–2281 (2022).

Article  PubMed  PubMed Central  Google Scholar 

Blindheim, A. et al. T1 bladder cancer in Norway: treatment and survival. Scand. J. Urol. 54, 370–375 (2020).

Article  PubMed  Google Scholar 

Mori, K. et al. Impact of sex on outcomes after surgery for non-muscle-invasive and muscle-invasive bladder urothelial carcinoma: a systematic review and meta-analysis. World J. Urol. https://doi.org/10.1007/s00345-022-04116-x (2022).

Article  PubMed  PubMed Central  Google Scholar 

Dobruch, J. et al. Gender and bladder cancer: a collaborative review of etiology, biology, and outcomes. Eur. Urol. 69, 300–310 (2016).

Article  PubMed  Google Scholar 

Foxman, B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Am. J. Med. 113, 5S–13S (2002).

Article  PubMed  Google Scholar 

Zhou, Y. et al. Quality of the diagnostic process in patients presenting with symptoms suggestive of bladder or kidney cancer: a systematic review. BMJ Open 9, e029143 (2019).

Article  PubMed  PubMed Central  Google Scholar 

Bolenz, C., Schroppel, B., Eisenhardt, A., Schmitz-Drager, B. J. & Grimm, M. O. The investigation of hematuria. Dtsch. Arztebl Int. 115, 801–807 (2018).

PubMed  PubMed Central  Google Scholar 

Lyratzopoulos, G., Abel, G. A., McPhail, S., Neal, R. D. & Rubin, G. P. Gender inequalities in the promptness of diagnosis of bladder and renal cancer after symptomatic presentation: evidence from secondary analysis of an English primary care audit survey. BMJ Open 3, 002861 (2013).

Article  Google Scholar 

Ngo, B., Perera, M., Papa, N., Bolton, D. & Sengupta, S. Factors affecting the timeliness and adequacy of haematuria assessment in bladder cancer: a systematic review. BJU Int. 119, 10–18 (2017).

Article  PubMed  Google Scholar 

Bryan, R. T. et al. A comparative analysis of the influence of gender, pathway delays, and risk factor exposures on the long-term outcomes of bladder cancer. Eur. Urol. Focus. 1, 82–89 (2015).

Article  PubMed  Google Scholar 

Zhou, Y. et al. Prolonged diagnostic intervals as marker of missed diagnostic opportunities in bladder and kidney cancer patients with alarm features: a longitudinal linked data study. Cancers https://doi.org/10.3390/cancers13010156 (2021).

Article  PubMed  PubMed Central  Google Scholar 

Danforth, K. N. et al. Care quality and variability in the use of intravesical therapy for initial treatment of nonmuscle invasive bladder cancer within a large, diverse integrated delivery system. Urology 131, 93–103 (2019).

Article  PubMed  Google Scholar 

Grajales, V. et al. Associations between female sex and treatment patterns and outcomes for muscle-invasive bladder cancer. Urology 151, 169–175 (2021).

Article  PubMed  Google Scholar 

Marinaro, J. et al. Sex and racial disparities in the treatment and outcomes of muscle-invasive bladder cancer. Urology 151, 154–162 (2021).

Article  PubMed  Google Scholar 

Heberling, U. et al. Gender and mortality after radical cystectomy: competing risk analysis. Urol. Int. 101, 293–299 (2018).

Article  PubMed  Google Scholar 

Farber, N. J. et al. Disparities in the use of continent urinary diversions after radical cystectomy for bladder cancer. Bladder Cancer 4, 113–120 (2018).