A 50-year-old woman was admitted to ICU following successful resuscitation after out of hospital cardiac arrest. She developed hypoxic brain injury and critical illness myopathy (CIM) resulting in flaccid weakness and prolonged ventilatory support. The patient was shifted to tertiary care facility and weaned from the ventiator. With multidisciplinary palliative care which included wound care, physiotherapist-assisted mobilization, and nutritional support, she showed significant improvement over 4 weeks, including improved muscle strength, swallowing, healing of pressure injury, and successful decannulation of tracheostomy.