Multimodality Imaging for Left Atrial Appendage Occlusion Devices

Blackshear JL, Odell JA. Appendage obliteration to reduce stroke in cardiac surgical patients with atrial fibrillation. Ann Thorac Surg. 1996;61(2):755–9.

Article  CAS  PubMed  Google Scholar 

Madden JL. Resection of the left auricular appendix; a prophylaxis for recurrent arterial emboli. J Am Med Assoc. 1949;140(9):769–72.

Article  CAS  PubMed  Google Scholar 

Turagam MK, Velagapudi P, Kar S, Holmes D, Reddy VY, Refaat MM, et al. Cardiovascular therapies targeting left atrial appendage. J Am Coll Cardiol. 2018;72(4):448–63.

Article  PubMed  PubMed Central  Google Scholar 

Sievert H, Lesh MD, Trepels T, Omran H, Bartorelli A, Della Bella P, et al. Percutaneous left atrial appendage transcatheter occlusion to prevent stroke in high-risk patients with atrial fibrillation: early clinical experience. Circulation. 2002;105(16):1887–9.

Article  PubMed  Google Scholar 

Asmarats L, Rodes-Cabau J. Percutaneous left atrial appendage closure: current devices and clinical outcomes. Circ Cardiovasc Interv. 2017;10(11):e005359.

Glikson M, Wolff R, Hindricks G, Mandrola J, Camm AJ, Lip GYH, et al. EHRA/EAPCI expert consensus statement on catheter-based left atrial appendage occlusion - an update. EuroIntervention. 2020;15(13):1133–80.

Article  PubMed  Google Scholar 

Freeman JV, Varosy P, Price MJ, Slotwiner D, Kusumoto FM, Rammohan C, et al. The NCDR left atrial appendage occlusion registry. J Am Coll Cardiol. 2020;75(13):1503–18.

Article  PubMed  PubMed Central  Google Scholar 

Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomstrom-Lundqvist C, et al. Corrigendum to: 2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European association for Cardio-Thoracic surgery (EACTS): the task force for the diagnosis and management of atrial fibrillation of the European society of cardiology (ESC) developed with the special contribution of the European heart rhythm association (EHRA) of the ESC. Eur Heart J. 2021;42(40):4194.

Article  PubMed  Google Scholar 

Jung RG, Simard T, Killu A, Harris AA, Hohmann SF, Holmes DR, et al. Learning curve and outcomes of left atrial appendage closure. JACC Cardiovasc Interv. 2021;14(24):2750–2.

Article  PubMed  Google Scholar 

Alkhouli M, Ellis CR, Daniels M, Coylewright M, Nielsen-Kudsk JE, Holmes DR. Left atrial appendage occlusion: current advances and remaining challenges. JACC Adv. 2022;1(5):100136.

Article  PubMed  PubMed Central  Google Scholar 

Holmes DR, Reddy VY, Turi ZG, Doshi SK, Sievert H, Buchbinder M, et al. Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial. Lancet. 2009;374(9689):534–42.

Article  CAS  PubMed  Google Scholar 

Holmes DR Jr., Kar S, Price MJ, Whisenant B, Sievert H, Doshi SK, et al. Prospective randomized evaluation of the watchman left atrial appendage closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial. J Am Coll Cardiol. 2014;64(1):1–12.

Article  PubMed  Google Scholar 

Lakkireddy D, Thaler D, Ellis CR, Swarup V, Sondergaard L, Carroll J, et al. Amplatzer amulet left atrial appendage occluder versus watchman device for stroke prophylaxis (Amulet IDE): A Randomized, controlled trial. Circulation. 2021;144(19):1543–52.

Article  PubMed  PubMed Central  Google Scholar 

Osmancik P, Herman D, Neuzil P, Hala P, Taborsky M, Kala P, et al. Left atrial appendage closure versus direct oral anticoagulants in High-Risk patients with atrial fibrillation. J Am Coll Cardiol. 2020;75(25):3122–35.

Article  CAS  PubMed  Google Scholar 

Merino A, Hauptman P, Badimon L, Badimon JJ, Cohen M, Fuster V, et al. Echocardiographic smoke is produced by an interaction of erythrocytes and plasma proteins modulated by shear forces. J Am Coll Cardiol. 1992;20(7):1661–8.

Article  CAS  PubMed  Google Scholar 

Wang Y, Di Biase L, Horton RP, Nguyen T, Morhanty P, Natale A. Left atrial appendage studied by computed tomography to help planning for appendage closure device placement. J Cardiovasc Electrophysiol. 2010;21(9):973–82.

Article  PubMed  Google Scholar 

Bernhardt P, Schmidt H, Hammerstingl C, Luderitz B, Omran H. Patients with atrial fibrillation and dense spontaneous echo contrast at high risk a prospective and serial follow-up over 12 months with transesophageal echocardiography and cerebral magnetic resonance imaging. J Am Coll Cardiol. 2005;45(11):1807–12.

Article  PubMed  Google Scholar 

Goldman ME, Pearce LA, Hart RG, Zabalgoitia M, Asinger RW, Safford R, et al. Pathophysiologic correlates of thromboembolism in nonvalvular atrial fibrillation: I. Reduced flow velocity in the left atrial appendage (The stroke prevention in atrial fibrillation [SPAF-III] study). J Am Soc Echocardiogr. 1999;12(12):1080–7.

Article  CAS  PubMed  Google Scholar 

Handke M, Harloff A, Hetzel A, Olschewski M, Bode C, Geibel A. Left atrial appendage flow velocity as a quantitative surrogate parameter for thromboembolic risk: determinants and relationship to spontaneous Echocontrast and thrombus formation–a transesophageal echocardiographic study in 500 patients with cerebral ischemia. J Am Soc Echocardiogr. 2005;18(12):1366–72.

Article  PubMed  Google Scholar 

Hahn RT, Saric M, Faletra FF, Garg R, Gillam LD, Horton K, et al. Recommended standards for the performance of transesophageal echocardiographic screening for structural heart intervention: from the American society of echocardiography. J Am Soc Echocardiogr. 2022;35(1):1–76.

Article  CAS  PubMed  Google Scholar 

Negrotto SM, Lugo RM, Metawee M, Kanagasundram AN, Chidsey G, Baker MT, et al. Left atrial appendage morphology predicts the formation of left atrial appendage thrombus. J Cardiovasc Electrophysiol. 2021;32(4):1044–52.

Article  PubMed  Google Scholar 

Hayes DE, Bamira D, Vainrib AF, Freedberg RS, Aizer A, Chinitz LA, et al. Left atrial appendage Tilt-Up-and-Turn-Left maneuver: A novel Three-Dimensional transesophageal echocardiography imaging maneuver to characterize the left atrial appendage and to improve transcatheter closure guidance. CASE (Phila). 2023;7(10):391–5.

Article  PubMed  PubMed Central  Google Scholar 

Di Biase L, Santangeli P, Anselmino M, Mohanty P, Salvetti I, Gili S, et al. Does the left atrial appendage morphology correlate with the risk of stroke in patients with atrial fibrillation? Results from a multicenter study. J Am Coll Cardiol. 2012;60(6):531–8.

Article  PubMed  Google Scholar 

Korsholm K, Berti S, Iriart X, Saw J, Wang DD, Cochet H, et al. Expert recommendations on cardiac computed tomography for planning transcatheter left atrial appendage occlusion. JACC Cardiovasc Interv. 2020;13(3):277–92.

Article  PubMed  Google Scholar 

Kubota T, Kawasaki M, Takasugi N, Takeyama U, Ishihara Y, Okubo M, et al. Evaluation of left atrial degeneration for the prediction of atrial fibrillation: usefulness of integrated backscatter transesophageal echocardiography. JACC Cardiovasc Imaging. 2009;2(9):1039–47.

Article  PubMed  Google Scholar 

Romero J, Husain SA, Kelesidis I, Sanz J, Medina HM, Garcia MJ. Detection of left atrial appendage thrombus by cardiac computed tomography in patients with atrial fibrillation: a meta-analysis. Circ Cardiovasc Imaging. 2013;6(2):185–94.

Article  PubMed  Google Scholar 

Ghozy S, Liu M, Kobeissi H, Mortezaei A, Amoukhteh M, Abbas AS, et al. Cardiac CT vs echocardiography for intracardiac thrombus detection in ischemic stroke: A systematic review and Meta-Analysis of 43 studies. Neurology. 2024;103(7):e209771.

Article  PubMed  Google Scholar 

Sattar Y, Kompella R, Ahmad B, Aamir M, Suleiman AM, Zghouzi M, et al. Comparison of left atrial appendage parameters using computed tomography vs. transesophageal echocardiography for watchman device implantation: a systematic review & meta-analysis. Expert Rev Cardiovasc Ther. 2022;20(2):151–60.

Article  CAS  PubMed  Google Scholar 

De Backer O, Iriart X, Kefer J, Nielsen-Kudsk JE, Aminian A, Rosseel L, et al. Impact of computational modeling on transcatheter left atrial appendage closure efficiency and outcomes. JACC Cardiovasc Interv. 2023;16(6):655–66.

Article  PubMed  Google Scholar 

Obasare E, Mainigi SK, Morris DL, Slipczuk L, Goykhman I, Friend E, et al. CT based 3D printing is superior to transesophageal echocardiography for pre-procedure planning in left atrial appendage device closure. Int J Cardiovasc Imaging. 2018;34(5):821–31.

PubMed  Google Scholar 

Bhuta S, Carlen A, Savona SJ, Augostini RS, Kalbfleisch SJ, Houmsse M, et al. Incidence and Temporal evolution of delayed peridevice leak after left atrial appendage closure. Heart Rhythm. 2024;21(11):2118–25.

Article  PubMed  Google Scholar 

Cepas-Guillen P, Holmes DR Jr., Cavalcante J, Freixa X, O’Hara G, Beaudoin J, et al. Imaging assessment after percutaneous left atrial appendage closure: from immediate to long-term follow-up. Eur Heart J Cardiovasc Imaging. 2025;26(6):993–1006.

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