Late-systolic to early-diastolic hemodynamic force analysis in ischemic heart disease using vector flow mapping and invasive pressure measurement

Pedrizzetti G, La Canna G, Alfieri O, Tonti G (2014) The vortex—an early predictor of cardiovascular outcome? Nat Rev Cardiol 11:545–553

Article  PubMed  Google Scholar 

Pedrizzetti G, Martiniello AR, Bianchi V, D’Onofrio A, Caso P, Tonti G (2015) Cardiac fluid dynamics anticipates heart adaptation. J Biomech 48:388–391

Article  PubMed  Google Scholar 

Eriksson J, Zajac J, Alehagen U, Bolger AF, Ebbers T, Carlhäll CJ (2017) Left ventricular hemodynamic forces as a marker of mechanical dyssynchrony in heart failure patients with left bundle branch block. Sci Rep 7:2971

Article  PubMed  PubMed Central  Google Scholar 

Arvidsson PM, Töger J, Pedrizzetti G, Heiberg E, Borgquist R, Carlsson M, Arheden H (2018) Hemodynamic forces using four-dimensional flow MRI: an independent biomarker of cardiac function in heart failure with left ventricular dyssynchrony? Am J Physiol Heart Circ Physiol 315:H1627–H1639

Article  CAS  PubMed  Google Scholar 

Vallelonga F, Airale L, Tonti G, Argulian E, Milan A, Narula J, Pedrizzetti G (2021) Introduction to hemodynamic forces analysis: moving into the new frontier of cardiac deformation analysis. J Am Heart Assoc 10:e023417

Article  PubMed  PubMed Central  Google Scholar 

Courtois M, Kovács SJ Jr, Ludbrook PA (1988) Transmitral pressure-flow velocity relation. Importance of regional pressure gradients in the left ventricle during diastole. Circulation 78:661–671

Article  CAS  PubMed  Google Scholar 

Ebbers T, Wigström L, Bolger AF, Engvall J, Karlsson M (2001) Estimation of relative cardiovascular pressures using time-resolved three-dimensional phase contrast MRI. Magn Reson Med 45:872–879

Article  CAS  PubMed  Google Scholar 

Pedrizzetti G, Martiniello AR, Bianchi V, D’Onofrio A, Caso P, Tonti G (2016) Changes in electrical activation modify the orientation of left ventricular flow momentum: novel observations using echocardiographic particle image velocimetry. Eur Heart J Cardiovasc Imaging 17:203–209

Article  PubMed  Google Scholar 

Pedrizzetti G (2019) On the computation of hemodynamic forces in the heart chambers. J Biomech 95:109323

Article  PubMed  Google Scholar 

Sabbah HN, Stein PD (1981) Pressure-diameter relations during early diastole in dogs. Incompatibility with the concept of passive left ventricular filling. Circ Res 48:357–365

Article  CAS  PubMed  Google Scholar 

Yellin EL, Hori M, Yoran C, Sonnenblick EH, Gabbay S, Frater RW (1986) Left ventricular relaxation in the filling and nonfilling intact canine heart. Am J Physiol 250:H620–H629

CAS  PubMed  Google Scholar 

Smiseth OA, Steine K, Sandbaek G, Stugaard M, Gjolberg T (1998) Mechanics of intraventricular filling: study of LV early diastolic pressure gradients and flow velocities. Am J Physiol 275:H1062–H1069

CAS  PubMed  Google Scholar 

Bello H, Norton GR, Peterson VR, Mmopi KN, Mthembu N, Libhaber CD, Masiu M, Da Silva Fernandes D, Bamaiyi AJ, Peters F, Sareli P, Woodiwiss AJ (2020) Hemodynamic determinants of age versus left ventricular diastolic function relations across the full adult age range. Hypertension 75:1574–1583

Article  CAS  PubMed  Google Scholar 

Yotti R, Bermejo J, Antoranz JC, Desco MM, Cortina C, Rojo-Alvarez JL, Allué C, Martín L, Moreno M, Serrano JA, Muñoz R, García-Fernández MA (2005) A noninvasive method for assessing impaired diastolic Suction in patients with dilated cardiomyopathy. Circulation 112:2921–2929

Article  PubMed  Google Scholar 

Töger J, Arvidsson PM, Bock J, Kanski M, Pedrizzetti G, Carlsson M, Arheden H, Heiberg E (2018) Hemodynamic forces in the left and right ventricles of the human heart using 4D flow magnetic resonance imaging: phantom validation, reproducibility, sensitivity to respiratory gating and free analysis software. PLoS ONE 13:e0195597

Article  PubMed  PubMed Central  Google Scholar 

Pola K, Roijer A, Borgquist R, Ostenfeld E, Carlsson M, Bakos Z, Arheden H, Arvidsson PM (2023) Hemodynamic forces from 4D flow magnetic resonance imaging predict left ventricular remodeling following cardiac resynchronization therapy. J Cardiovasc Magn Reson 25:45

Article  PubMed  PubMed Central  Google Scholar 

Itatani K, Okada T, Uejima T, Tanaka T, Ono M, Miyaji K, Takenaka K (2013) Intraventricular flow velocity vector visualization based on the continuity equation and measurements of vorticity and wall shear stress. Jpn J Appl Phys 52:07HF16

Article  Google Scholar 

Minami S, Masuda K, Stugaard M, Kamimukai T, Asanuma T, Nakatani S (2021) Noninvasive assessment of intraventricular pressure difference in left ventricular dyssynchrony using vector flow mapping. Heart Vessels 36:92–98

Article  PubMed  Google Scholar 

Firstenberg MS, Smedira NG, Greenberg NL, Prior DL, McCarthy PM, Garcia MJ, Thomas JD (2001) Relationship between early diastolic intraventricular pressure gradients, an index of elastic recoil, and improvements in systolic and diastolic function. Circulation 104(Suppl 1):I330–I335

Article  CAS  PubMed  Google Scholar 

Sørensen K, Fadnes S, Mawad W, Henry M, Flade HM, Østvik A, Myklebust TÅ, Kirkeby-Garstad I, Løvstakken L, Mertens L, Nyrnes SA (2025) Intraventricular pressure difference Estimation based on blood speckle tracking-invasive validation and early clinical application. Eur Heart J Cardiovasc Imaging 26:1346–1357

Article  PubMed  PubMed Central  Google Scholar 

Uema A, Tamura Y, Uejima T, Hoshiai M, Ueno A, Nagao M, Tomoe T, Ono S, Maeno E, Mizuguchi S, Kawabe A, Sugiyama T, Yasu T (2022) Early diastolic mitral regurgitation in left ventricular aneurysm. Heart Vessels 37:683–690

Article  PubMed  Google Scholar 

Warisawa T, Nour D, Seligman H, Doi S, Kuwata S, Howard JP, Rajkumar C, Cook CM, Nakayama Y, Kasahara M, Suzuki N, Matsuda H, Mizuno K, Akashi YJ (2020) Interference between pressure-wire and deployed coronary stents: insights from a bench test. Cardiovasc Revasc Med 21:765–770

Article  PubMed  Google Scholar 

Cottens D, Ferdinande B, Polad J, Vrolix M, Ameloot K, Hendrickx I, Poels E, Maeremans J, Dens J (2022) FFR pressure wire comparative study for drift: piezo resistive versus optical sensor. Am J Cardiovasc Dis 12:42–52

PubMed  PubMed Central  Google Scholar 

Murayama M, Iwano H, Obokata M, Harada T, Omote K, Kagami K, Tsujinaga S, Chiba Y, Ishizaka S, Motoi K, Tamaki Y, Aoyagi H, Nakabachi M, Nishino H, Yokoyama S, Tanemura A, Okada K, Kaga S, Nishida M, Nagai T, Kurabayashi M, Anzai T (2022) Visual echocardiographic scoring system of the left ventricular filling pressure and outcomes of heart failure with preserved ejection fraction. Eur Heart J Cardiovasc Imaging 23:616–626

Article  PubMed  PubMed Central  Google Scholar 

Murayama M, Iwano H, Nishino H, Tsujinaga S, Nakabachi M, Yokoyama S, Aiba M, Okada K, Kaga S, Sarashina M, Chiba Y, Ishizaka S, Motoi K, Nishida M, Shibuya H, Kamiya K, Nagai T, Anzai T (2021) Simple two-dimensional echocardiographic scoring system for the Estimation of left ventricular filling pressure. J Am Soc Echocardiogr 34:723–734

Article  PubMed  Google Scholar 

Yotti R, Bermejo J, Benito Y, Antoranz JC, Desco MM, Rodríguez-Pérez D, Cortina C, Mombiela T, Barrio A, Elízaga J, Fernández-Avilés F (2011) Noninvasive Estimation of the rate of relaxation by the analysis of intraventricular pressure gradients. Circ Cardiovasc Imaging 4:94–104

Article  PubMed  Google Scholar 

Tanaka T, Okada T, Nishiyama T, Seki Y (2017) Relative pressure imaging in left ventricle using ultrasonic vector flow mapping. Jpn J Appl Phys 56:07JF26

Article  Google Scholar 

Asami R, Tanaka T, Kawabata KI, Hashiba K, Okada T, Nishiyama T (2017) Accuracy and limitations of vector flow mapping: left ventricular Phantom validation using stereo particle image velocimetory. J Echocardiogr 15:57–66

Article  PubMed  Google Scholar 

Taniguchi N, Miyasaka Y, Suwa Y, Nakai E, Harada S, Otagaki H, Shiojima I (2024) Incremental value of diastolic wall strain in predicting heart failure events in patients with atrial fibrillation. Heart Vessels 39:785–794

Article  PubMed  Google Scholar 

Gong C, Kinoshita T, Hayashida M, Hara A, Kakemizu-Watanabe M, Miyazaki S, Tabata M (2025) The role of E-wave velocity in predicting early left ventricular dysfunction and significant decline in left ventricular ejection fraction after mitral valve repair for severe chronic primary mitral regurgitation. Heart Vessels 40:320–331

Article  PubMed  Google Scholar 

Peverill RE, Ngian GS, Mylrea C, Sahhar J (2021) Determinants of left ventricular structure, filling and long axis function in systemic sclerosis. PLoS ONE 16:e0258593

Article  CAS  PubMed  PubMed Central 

Comments (0)

No login
gif