Effects of Rivaroxaban on Prognosis in Patients with Acute Myocardial Infarction and Preexisting Atrial Fibrillation

Announcing a new article publication for Cardiovascular Innovations and Applications journal. A new real-world analysis using data from the Tianjin Health and Medical Big Data Super Platform provides the first large-scale clinical insights from Asia into anticoagulation practices for patients with acute myocardial infarction (AMI) and preexisting atrial fibrillation (AF), a population known to be at heightened risk for adverse cardiovascular events.

This study addresses a critical evidence gap regarding the contemporary use of direct oral anticoagulants alongside antiplatelet therapy, revealing that rivaroxaban is prescribed in combination therapy in 18.7% of Chinese patients with AMI and AF. The findings show that rivaroxaban use is associated with a reduced risk of stroke without an accompanying increase in bleeding events, offering new evidence to inform clinical decision-making for this high-risk population.

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Ying Liu, Yi Zheng and Gregory Y. H. Lip et al. Effects of Rivaroxaban on Prognosis in Patients with Acute Myocardial Infarction and Preexisting Atrial Fibrillation. CVIA. 2025. Vol. 10(1). DOI: 10.15212/CVIA.2025.0028

Cardiovascular Innovations and Applications is indexed in the SCOPUS, EMBASE, EBSCO, ESCI, OCLC, Primo Central (Ex Libris), Sherpa Romeo, NISC (National Information Services Corporation), DOAJ, Index Copernicus, Research4Life, CNKI Scholar (Chinese National Knowledge Infrastructure) and Ulrich’s web Databases.