Siegel RL, Kratzer TB, Giaquinto AN, Sung H, Jemal A. Cancer statistics, 2025. CA Cancer J Clin. 2025;75(1):10–45.
PubMed PubMed Central Google Scholar
Hernández-Silva CD, de Ramírez Arellano A, Pereira-Suárez AL, Ramírez-López IG. HPV and cervical cancer: molecular and immunological aspects, epidemiology and effect of vaccination in Latin American women. Viruses. 2024. https://doi.org/10.3390/v16030327.
Article PubMed PubMed Central Google Scholar
Mayadev JS, Ke G, Mahantshetty U, Pereira MD, Tarnawski R, Toita T. Global challenges of radiotherapy for the treatment of locally advanced cervical cancer. Int J Gynecol Cancer. 2022;32(3):436–45.
Article PubMed PubMed Central Google Scholar
Poddar P, Maheshwari A. Surgery for cervical cancer: consensus & controversies. Indian J Med Res. 2021;154(2):284–92. https://doi.org/10.4103/ijmr.IJMR_4240_20.
Article PubMed PubMed Central Google Scholar
Khan S, Gerber DE. Autoimmunity, checkpoint inhibitor therapy and immune-related adverse events: a review. Semin Cancer Biol. 2020;64:93-101.
Yousuf S, Qiu M, von Voith Voithenberg L, Hulkkonen J, Macinkovic I, Schulz AR, et al. Spatially resolved multi-omics single-cell analyses inform mechanisms of immune dysfunction in pancreatic cancer. Gastroenterology. 2023;165(4):891-908.e14.
Article CAS PubMed Google Scholar
Gutiérrez-Hoya A, Soto-Cruz I. NK cell regulation in cervical cancer and strategies for immunotherapy. Cells. 2021. https://doi.org/10.3390/cells10113104.
Article PubMed PubMed Central Google Scholar
Fan J, Lu F, Qin T, Peng W, Zhuang X, Li Y, et al. Multiomic analysis of cervical squamous cell carcinoma identifies cellular ecosystems with biological and clinical relevance. Nat Genet. 2023;55(12):2175–88.
Article CAS PubMed Google Scholar
Yan H, Bu P. Non-coding RNA in cancer. Essays Biochem. 2021;65(4):625–39. https://doi.org/10.1042/EBC20200032.
Article CAS PubMed PubMed Central Google Scholar
Zhang J, Xiong C, Wei X, Yang H, Zhao C. Modeling ncRNA synergistic regulation in cancer. Methods Mol Biol. 2025;2883:377-402.
Grammatikakis I, Lal A. Significance of lncRNA abundance to function. Mamm Genome. 2022;33(2):271–80.
Article CAS PubMed Google Scholar
Tan YT, Lin JF, Li T, Li JJ, Xu RH, Ju HQ. LncRNA-mediated posttranslational modifications and reprogramming of energy metabolism in cancer. Cancer Commun. 2021;41(2):109–20.
Liu PW, Liu ZY, Deng SJ, Zhang X, Wang ZB, Wu NY, et al. A pyroptosis-related LncRNA signature for predicting prognosis, immune features and drug sensitivity in ovarian cancer. Onco Targets Ther. 2025;18:585–601.
Article PubMed PubMed Central Google Scholar
Xia Z, Wu J, Li Y, Yuan X, Sun J, Lv C, et al. LncRNA TYMSOS is a novel prognostic biomarker associated with immune infiltration in prostate cancer. Am J Cancer Res. 2023;13(10):4531–46.
CAS PubMed PubMed Central Google Scholar
Entezari M, Taheriazam A, Orouei S, Fallah S, Sanaei A, Hejazi ES, et al. LncRNA-miRNA axis in tumor progression and therapy response: an emphasis on molecular interactions and therapeutic interventions. Biomed Pharmacother. 2022;154:113609.
Article CAS PubMed Google Scholar
Yang L, Li LP, Yi HC. DeepWalk based method to predict lncRNA-miRNA associations via lncRNA-miRNA-disease-protein-drug graph. BMC Bioinform. 2022;22(Suppl 12):621.
Shen T, Wang W, Wang H, Zhu X, Zhu G. Mitochondrial miRNA miR-134-5p play oncogenic role in clear cell renal cell carcinoma. Biomolecules. 2025. https://doi.org/10.3390/biom15030445.
Article PubMed PubMed Central Google Scholar
Yan L, Zhou R, Feng Y, Li R, Zhang L, Pan Y, et al. MiR-134-5p inhibits the malignant phenotypes of osteosarcoma via ITGB1/MMP2/PI3K/Akt pathway. Cell Death Discov. 2024;10(1):193.
Article CAS PubMed PubMed Central Google Scholar
Zhang WY, Liu YJ, He Y, Chen P. Suppression of long noncoding RNA NCK1-AS1 increases chemosensitivity to cisplatin in cervical cancer. J Cell Physiol. 2019;234(4):4302–13.
Article CAS PubMed Google Scholar
Wang J, Lupo KB, Chambers AM, Matosevic S. Purinergic targeting enhances immunotherapy of CD73(+) solid tumors with piggyBac-engineered chimeric antigen receptor natural killer cells. J Immunother Cancer. 2018;6(1):136.
Article PubMed PubMed Central Google Scholar
Fang P, Xiang L, Chen W, Li S, Huang S, Li J, et al. LncRNA GAS5 enhanced the killing effect of NK cell on liver cancer through regulating miR-544/RUNX3. Innate Immun. 2019;25(2):99–109.
Article CAS PubMed PubMed Central Google Scholar
Jia J, Liu Y, Yang X, Wu Z, Xu X, Kang F, et al. IncRNA TYMSOS promotes epithelial-mesenchymal transition and metastasis in thyroid carcinoma through regulating MARCKSL1 and activating the PI3K/Akt signaling pathway. Crit Rev Eukaryot Gene Expr. 2022;33(1):1–14.
Zhang Z, Wang J, Zhang X, Ran B, Wen J, Zhang H. TYMSOS-miR-101-3p-NETO2 axis promotes osteosarcoma progression. Mol Cell Probes. 2023;67:101887.
Article CAS PubMed Google Scholar
Gu Y, Wan C, Zhou G, Zhu J, Shi Z, Zhuang Z. TYMSOS drives the proliferation, migration, and invasion of gastric cancer cells by regulating ZNF703 via sponging miR-4739. Cell Biol Int. 2021;45(8):1710–9.
Article CAS PubMed Google Scholar
Park EG, Pyo SJ, Cui Y, Yoon SH, Nam JW. Tumor immune microenvironment lncRNAs. Brief Bioinform. 2022;23(1):bbab504. https://doi.org/10.1093/bib/bbab504.
Zhang KJ, Tan XL, Guo L. LncRNA TYMSOS facilitates breast cancer metastasis and immune escape through downregulating ULBP3. iScience. 2023;26(9):107556.
Article CAS PubMed PubMed Central Google Scholar
Wang QM, Lian GY, Sheng SM, Xu J, Ye LL, Min C, et al. Exosomal lncRNA NEAT1 inhibits NK-cell activity to promote multiple myeloma cell immune escape via an EZH2/PBX1 axis. Mol Cancer Res. 2024;22(2):125–36. https://doi.org/10.1158/1541-7786.MCR-23-0282.
Article CAS PubMed Google Scholar
Chi J, Liu T, Shi C, Luo H, Wu Z, Xiong B, et al. Long non-coding RNA LUCAT1 promotes proliferation and invasion in gastric cancer by regulating miR-134-5p/YWHAZ axis. Biomed Pharmacother. 2019;118:109201.
Article CAS PubMed Google Scholar
Li P, Huang G. Long noncoding RNA LINC00858 promotes the progression of ovarian cancer via regulating the miR-134-5p/TRIM44 axis. J Recept Signal Transduct Res. 2022;42(4):382–9. https://doi.org/10.1080/10799893.2021.1968433.
Article CAS PubMed Google Scholar
Xi C, Ye NY, Wang YB. LncRNA LINC01278 accelerates colorectal cancer progression via miR-134-5p/KDM2A axis. Eur Rev Med Pharmacol Sci. 2020;24(20):10526–34.
Singhal A, Li BT, O’Reilly EM. Targeting KRAS in cancer. Nat Med. 2024;30(4):969–83.
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