Ward PA. Acute and chronic inflammation. Fundamentals Inflamm. 2010;3:1–16. https://doi.org/10.1017/CBO9781139195737.

Article  Google Scholar 

Hotamisligil GS. Inflammation, metaflammation and immunometabolic disorders. Nature. 2017;542:177–85. https://doi.org/10.1038/nature21363.

Article  PubMed  CAS  Google Scholar 

Mansouri V, Vafaee R, Mohammadi Maram M, Bandarian F, Sarabi P, Razi F, Razzaghi Z, Rezaei Tavirani M, Karimi H, Rezaei-Tavirani M. Inflammation and immunological disarrays are associated with acute exercise in type 2 diabetes. J Diabetes Metab Disord. 2024;23:1243–50. https://doi.org/10.1007/s40200-024-01417-3.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gregor MF, Hotamisligil GS. Inflammatory mechanisms in obesity. Annu Rev Immunol. 2011;29:415–45. https://doi.org/10.1146/annurev-immunol-031210-101322.

Article  PubMed  CAS  Google Scholar 

Rezaei-Tavirani S, Rostami-Nejad M, Vafaee R, Khalkhal E, Keramatinia A, Ehsani-Ardakani MJ, Razzaghi M. Introducing tumor necrosis factor as a prominent player in Celiac disease and type 1 diabetes mellitus. Gastroenterol Hepatol Bed Bench. 2019;12:S123.

PubMed  PubMed Central  Google Scholar 

Li H, Meng Y, He S, Tan X, Zhang Y, Zhang X, Wang L, Zheng W. Macrophages, chronic inflammation, and insulin resistance. Cells. 2022;11:3001. https://doi.org/10.3390/cells11193001.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Donath MY, Böni-Schnetzler M, Ellingsgaard H, Ehses JA. Islet inflammation impairs the pancreatic β-cell in type 2 diabetes. Physiology. 2009;24:325–31. https://doi.org/10.1152/physiol.00032.2009.

Article  PubMed  CAS  Google Scholar 

Nellaiappan K, Preeti K, Khatri DK, Singh SB. Diabetic complications: an update on pathobiology and therapeutic strategies. Curr Diabetes Rev. 2022;18:31–44. https://doi.org/10.2174/1573399817666210309104203.

Article  CAS  Google Scholar 

Jin Q, Liu T, Qiao Y, Liu D, Yang L, Mao H, Ma F, Wang Y, Peng L, Zhan Y. Oxidative stress and inflammation in diabetic nephropathy: role of polyphenols. Front Immunol. 2023;14:1185317. https://doi.org/10.3389/fimmu.2023.1185317.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Parameswaran M, Hasan HA, Sadeque J, Jhaveri S, Avanthika C, Arisoyin AE, Dhanani MB, Rath SM, Hasan HA Jr. Factors that predict the progression of non-alcoholic fatty liver disease (NAFLD). Cureus. 2021;13. https://doi.org/10.7759/cureus.20776.

Lee CH, Lui DT, Lam KS. Non-alcoholic fatty liver disease and type 2 diabetes: an update. J Diabetes Investig. 2022;13:930–40. https://doi.org/10.1111/jdi.13756.

Article  PubMed  PubMed Central  Google Scholar 

Pouwels S, Sakran N, Graham Y, Leal A, Pintar T, Yang W, Kassir R, Singhal R, Mahawar K, Ramnarain D. Non-alcoholic fatty liver disease (NAFLD): a review of pathophysiology, clinical management and effects of weight loss. BMC Endocr Disord. 2022;22:63. https://doi.org/10.1186/s12902-022-00980-1.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Tacke F, Weiskirchen R. Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention. Ann Transl Med. 2021;9:729. https://doi.org/10.21037/atm-20-4354.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Gaber T, Strehl C, Buttgereit F. Metabolic regulation of inflammation. Nat Rev Rheumatol. 2017;13:267–79. https://doi.org/10.1038/nrrheum.2017.37.

Article  PubMed  Google Scholar 

Zhou M, Zhang Y, Shi L, Li L, Zhang D, Gong Z, et al. Activation and modulation of the AGEs-RAGE axis: implications for inflammatory pathologies and therapeutic interventions - a review. Pharmacol Res. 2024;206:107282. https://doi.org/10.1016/j.phrs.2024.107282.

Article  PubMed  CAS  Google Scholar 

Jubaidi FF, Zainalabidin S, Taib IS, Abdul Hamid Z, Mohamad Anuar NN, Jalil J, et al. The role of PKC-MAPK signalling pathways in the development of hyperglycemia-induced cardiovascular complications. Int J Mol Sci. 2022;23:8582. https://doi.org/10.3390/ijms23158582.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Thorne CA, Grey AC, Lim JC, Donaldson PJ. The synergistic effects of polyol pathway-induced oxidative and osmotic stress in the aetiology of diabetic cataracts. Int J Mol Sci. 2024;25:9042. https://doi.org/10.3390/ijms25169042.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Garg SS, Gupta J. Polyol pathway and redox balance in diabetes. Pharmacol Res. 2022;182:106326. https://doi.org/10.1016/j.phrs.2022.106326.

Article  PubMed  CAS  Google Scholar 

Rai AK, Jaiswal N, Maurya CK, Sharma A, Ahmad I, Ahmad S, Gupta AP, Gayen JR, Tamrakar AK. Fructose-induced AGEs-RAGE signaling in skeletal muscle contributes to impairment of glucose homeostasis. J Nutr Biochem. 2019;71:35–44. https://doi.org/10.1016/j.jnutbio.2019.05.016.

Article  PubMed  CAS  Google Scholar 

Wang Y, Fang X, Wang S, Wang B, Chu F, Tian Z, Zhang L, Zhou F. The role of O-GlcNAcylation in innate immunity and inflammation. J Mol Cell Biol. 2022;14:mjac065. https://doi.org/10.1093/jmcb/mjac065.

Article  PubMed Central  CAS  Google Scholar 

Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science. 2005;307:384–7. https://doi.org/10.1126/science.1104343.

Article  PubMed  CAS  Google Scholar 

Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature. 2011;469:221–5. https://doi.org/10.1038/nature09663.

Article  PubMed  CAS  Google Scholar 

Dandekar A, Mendez R, Zhang K. Cross talk between ER stress, oxidative stress, and inflammation in health and disease, stress responses: methods and protocols. 2015;205–14. https://doi.org/10.1007/978-1-4939-2522-3_15.

Ma X, Nan F, Liang H, Shu P, Fan X, Song X, Hou Y, Zhang D. Excessive intake of sugar: an accomplice of inflammation. Front Immunol. 2022;13:988481. https://doi.org/10.3389/fimmu.2022.988481.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Torres-Castro I, Arroyo-Camarena ÚD, Martínez-Reyes CP, Gómez-Arauz AY, Dueñas-Andrade Y, Hernández-Ruiz J, Béjar YL, Zaga-Clavellina V, Morales-Montor J, Terrazas LI. Human monocytes and macrophages undergo M1-type inflammatory polarization in response to high levels of glucose. Immunol Lett. 2016;176:81–9. https://doi.org/10.1016/j.imlet.2016.06.001.

Article  PubMed  CAS  Google Scholar 

Lee H, Kim M-J, Lee I-K, Hong C-W, Jeon J-H. Impact of hyperglycemia on immune cell function: a comprehensive review. Diabetol Int. 2024;15:745–60. https://doi.org/10.1007/s13340-024-00741-6.

Article  PubMed  PubMed Central  Google Scholar 

Gao Z, Hwang D, Bataille F, Lefevre M, York D, Quon MJ, et al. Serine phosphorylation of insulin receptor substrate 1 by inhibitor κB kinase complex. J Biol Chem. 2002;277:48115–21. https://doi.org/10.1074/jbc.M209459200.

Article  PubMed  CAS  Google Scholar 

Baker RG, Hayden MS, Ghosh S. NF-κB, inflammation, and metabolic disease. Cell Metab. 2011;13:11–22. https://doi.org/10.1016/j.cmet.2010.12.008.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science. 2005;307:384–7.

Article  PubMed  CAS