Zhu J, Hu Z, Luo Y, Liu Y, Luo W, Du X et al. Diabetic peripheral neuropathy: pathogenetic mechanisms and treatment. Front Endocrinol (Lausanne) [Internet]. 2023; 14:1265372. Available from: https://doi.org/10.3389/fendo.2023.1265372

Akter N. Diabetic peripheral neuropathy: epidemiology, physiopathology, diagnosis and treatment. Delta Med Coll J [Internet]. 2019;7(1):35–48. https://doi.org/10.3329/dmcj.v7i1.40619.

Article  Google Scholar 

Laddad M, Bahulekar A, Ghorpade VV. Peripheral neuropathy: A review of epidemiology, pathophysiology, and management options. OGF [Internet]. 2024 [cited 2024 Nov 24];34(3s):635–44. Available from: https://www.obstetricsandgynaecologyforum.com/index.php/ogf/article/view/326

Mallick-Searle T, Adler JA. Update on treating painful diabetic peripheral neuropathy: a review of current US guidelines with a focus on the most recently approved management options. J Pain Res. 2024;17:1005–28. https://doi.org/10.2147/JPR.S442595.

Article  PubMed  PubMed Central  Google Scholar 

Gandhi M, Fargo E, Prasad-Reddy L, Mahoney KM, Isaacs D. Diabetes: how to manage diabetic peripheral neuropathy. Drugs in Context. 2022. https://doi.org/10.7573/dic.2021-10-2.

Article  PubMed  PubMed Central  Google Scholar 

Atmaca A, Ketenci A, Sahin I, Sengun IS, Oner RI, Erdem Tilki H, et al. Expert opinion on screening, diagnosis, and management of diabetic peripheral neuropathy: a multidisciplinary approach. Front Endocrinol (Lausanne). 2024;15:1380929. https://doi.org/10.3389/fendo.2024.1380929.

Article  PubMed  Google Scholar 

Ray J, Sahoo CK, Mohanty R, Sahoo R, Dalai R. A review on diabetic peripheral neuropathy. J Drug Deliv Ther. 2021;11(2-S):121–5. https://doi.org/10.22270/jddt.v11i2-s.4642.

Article  CAS  Google Scholar 

Geeso J, Galan C. Diabetic Neuropathic Pain: Pathophysiology & Treatment [Internet]. Preprints. 2023. Available from: https://doi.org/10.20944/preprints202305.1240.v1

Yorek M. Combination therapy is it in the future for successfully treating peripheral diabetic neuropathy? Front Endocrinol (Lausanne). 2024;15:1357859. https://doi.org/10.3389/fendo.2024.1357859.

Article  PubMed  Google Scholar 

Niimi N, Yako H, Takaku S, Chung SK. Aldose reductase and the polyol pathway in Schwann cells: old and new problems. Int J Mol Sci. 2021;22(3):1031. https://doi.org/10.3390/ijms22031031.

Article  PubMed  PubMed Central  CAS  Google Scholar 

M SL, O P. Inflammatory biomarkers as a part of diagnosis in diabetic peripheral neuropathy. J Diabetes Metab Disord. 2021;20(1):869–82. https://doi.org/10.1007/s40200-021-00734-1.

Article  PubMed  PubMed Central  Google Scholar 

Akram R, Anwar H, Javed MS, Imran A, Rasul A, Malik SA, et al. Natural molecules as promising players against diabetic peripheral neuropathy: an emerging nutraceutical approach. Int J Food Prop. 2023;26(1):894–914. https://doi.org/10.1080/10942912.2023.2189569.

Article  CAS  Google Scholar 

Pathak R, Sachan N, Chandra P. Mechanistic approach towards diabetic neuropathy screening techniques and future challenges: A review. Biomed Pharmacother [Internet]. 2022;150(113025):113025. Available from: https://doi.org/10.1016/j.biopha.2022.113025

Mizukami H, Osonoi S. Pathogenesis and molecular treatment strategies of diabetic neuropathy collateral glucose-utilizing pathways in diabetic polyneuropathy. Int J Mol Sci [Internet]. 2020;22(1):94. Available from: https://doi.org/10.3390/ijms22010094

Lv Y, Yao X, Li X, Ouyang Y, Fan C, Qian Y. Cell metabolism pathways involved in the pathophysiological changes of diabetic peripheral neuropathy. Neural Regen Res. 2024;19(3):598–605. https://doi.org/10.4103/1673-5374.380872.

Article  PubMed  CAS  Google Scholar 

Ab Hamid, N., Omar, N., Ismail, C. A. N., & Long, I. (2021). Insight of Mechanism and Signaling Pathway in Pathogenesis of Diabetic Neuropathy: A Review: Pathogenesis of Diabetic Neuropathy. IIUM Medical Journal Malaysia, 20(4).

Saleh, D. O., & Sedik, A. A. (2024). Novel drugs affecting diabetic peripheral neuropathy. Iranian Journal of Basic Medical Sciences, 27(6), 657.

Jubaidi FF, Zainalabidin S, Taib IS, Abdul Hamid Z, Mohamad Anuar NN, Jalil J, et al. The role of PKC-MAPK signaling pathways in the development of hyperglycemia-induced cardiovascular complications. Int J Mol Sci. 2022;23(15):8582. https://doi.org/10.3390/ijms23158582.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Tang H-Y, Jiang A-J, Ma J-L, Wang F-J, Shen G-M. Understanding the signaling pathways related to the mechanism and treatment of diabetic peripheral neuropathy. Endocrinology. 2019;160(9):2119–27. https://doi.org/10.1210/en.2019-00311.

Article  PubMed  CAS  Google Scholar 

Feldman EL, Nave K-A, Jensen TS, Bennett DLH. New Horizons in diabetic neuropathy: Mechanisms, bioenergetics, and pain. Neuron. 2017;93(6):1296–313. https://doi.org/10.1016/j.neuron.2017.02.005.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Pan D, Xu L, Guo M. The role of protein kinase C in diabetic microvascular complications. Front Endocrinol (Lausanne). 2022;13:973058. https://doi.org/10.3389/fendo.2022.973058.

Article  PubMed  Google Scholar 

Ratan Y, Rajput A, Pareek A, Pareek A, Kaur R, Sonia S, et al. Recent advances in biomolecular patho-mechanistic pathways behind the development and progression of diabetic neuropathy. Biomedicines. 2024;12(7):1390. https://doi.org/10.3390/biomedicines12071390.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Pang L, Lian X, Liu H, Zhang Y, Li Q, Cai Y, et al. Understanding diabetic neuropathy: focus on oxidative stress. Oxid Med Cell Longev. 2020;2020:9524635. https://doi.org/10.1155/2020/9524635.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Weng L, Zhang F, Wang R, Ma W, Song Y. A review on protective role of genistein against oxidative stress in diabetes and related complications. Chem Biol Interact. 2019;310:108665. https://doi.org/10.1016/j.cbi.2019.05.031.

Article  PubMed  CAS  Google Scholar 

Singh A, Kukreti R, Saso L, Kukreti S. Mechanistic insight into oxidative stress-triggered signaling pathways and type 2 diabetes. Molecules. 2022;27(3):950. https://doi.org/10.3390/molecules27030950.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Redza-Dutordoir M, Averill-Bates DA. Interactions between reactive oxygen species and autophagy: Special issue: Death mechanisms in cellular homeostasis. Biochim Biophys Acta Mol Cell Res [Internet]. 2021;1868(8):119041. Available from: https://doi.org/10.1016/j.bbamcr.2021.119041

Mahmood DF, Ahmad DS. Pathophysiology and pharmacotherapeutics of diabetic neuropathy: a review. Sch J Appl Med Sci. 2022;10(12):2096–102. https://doi.org/10.36347/sjams.2022.v10i12.009.

Article  Google Scholar 

Bellier J, Nokin M-J, Lardé E, Karoyan P, Peulen O, Castronovo V, et al. Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer. Diabetes Res Clin Pract. 2019;148:200–11. https://doi.org/10.1016/j.diabres.2019.01.002.

Article  PubMed  CAS  Google Scholar 

Wu T-H, Tsai S-C, Lin H-W, Chen C-N, Hwu C-M. Increased serum levels of advanced glycation end products are negatively associated with relative muscle strength in patients with type 2 diabetes mellitus. BMC Endocr Disord. 2022;22(1):118. https://doi.org/10.1186/s12902-022-01035-1.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Zhao X-W, Yue W-X, Zhang S-W, Chen Q. Correlation between the accumulation of skin glycosylation end products and the development of type 2 diabetic peripheral neuropathy. BMC Endocr Disord. 2022;22(1):106. https://doi.org/10.1186/s12902-022-00997-6.

Article  PubMed  PubMed Central  CAS  Google Scholar 

Al-Saoudi E, Christensen MMB, Nawroth P, Fleming T, Hommel EE, Jørgensen ME, et al. Advanced glycation end-products are associated with diabetic neuropathy in young adults with type 1 diabetes. Front Endocrinol (Lausanne). 2022;13:891442. https://doi.org/10.3389/fendo.2022.891442.

Article  PubMed  Google Scholar 

Yang K, Wang Y, Li Y-W, Chen Y-G, Xing N, Lin H-B, et al. Progress in the treatment of diabetic peripheral neuropathy. Biomed Pharmacother. 2022;148:112717. https://doi.org/10.1016/j.biopha.2022.112717.

Article  PubMed  CAS  Google Scholar 

Khdour MR. Treatment of diabetic peripheral neuropathy: a review. J Pharm Pharmacol. 2020;72(7):863–72. https://doi.org/10.1111/jphp.13241.

Article  PubMed  CAS  Google Scholar 

Pop-Busui R, Ang L, Boulton A, Feldman E, Marcus R, Mizokami-Stout K, et al. Diagnosis and treatment of painful diabetic peripheral neuropathy. ADA Clinical Compendia. 2022;2022(1):1–32. https://doi.org/10.2337/db2022-01.

Article  Google Scholar 

Onakpoya, I. J., Thomas, E. T., Lee, J. J., Goldacre, B., & Heneghan, C. J. (2019). Benefits and harms of pregabalin in the management of neuropathic pain: a