Arteriovenous malformations (AVMs) present significant treatment challenges due to their hemorrhage risk and associated neurological deficits. Stereotactic radiosurgery (SRS) is a technique designed to obliterate AVMs while minimizing complications.

This study aims to evaluate the obliteration rate and clinical outcomes of patients undergoing SRS using linear accelerators (LINAC) for the treatment of brain AVMs.

This retrospective and prospective study included 56 consecutive patients who underwent SRS for AVMs between 2008 and 2021, with the study period till 2023. The mean patient age was 29.21 years (range: 8–67 years). Complete obliteration rates and clinical improvements were assessed, and statistical analysis was conducted using SPSS.

The mean planning target volume was 11.39 cc (median: 7.74 cc) and the average modified AVM score was 1.79 (median: 1.56). The obliteration rate was 83.92%, with 7.1% of patients exhibiting residual AVM and 5.3% requiring surgical excision. Post-radiation hemorrhage occurred in 7.14% of cases.

LINAC-based SRS proves to be a highly effective and safe treatment modality for small or surgically inaccessible brain AVMs.

P.K.R.G.: study design, data collection, manuscript writing, and data analysis. A.B.: study design, manuscript proof reading, and data analysis. A.H.: study design, manuscript proof reading, and data analysis. A.K.: study design and manuscript writing. R.S.: study design, manuscript proof reading, and data interpretation. A.K.: manuscript writing and data collection. C.P.: manuscript writing and data collection. N.D.: study design, manuscript writing, and data analysis. S.K.V.: manuscript writing and proof reading, and data analysis. R.H.: manuscript writing and data analysis.

Article published online:
28 July 2025

© 2025. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India