Introduction Sarcopenia has been associated with an increased risk of falls in diverse populations. Patients with end-stage kidney disease (ESRD) undergoing hemodialysis (HD) have an increased prevalence of muscle weakness and wasting. The aim of this study was to investigate the association between parameters of sarcopenia and a history of falls in ESRD patients in HD.
Methods A cross-sectional study design was utilized to assess 111 participants with ESRD in HD (54 ± 15.6 years; 59.5% men) in a tertiary hospital in Maringa-PR. Sarcopenia status was determined through the measure of muscle strength and mass. Muscle strength was assessed through hand grip strength utilizing a handheld dynamometer. Muscle mass was estimated through bioelectrical impedance. Falls’ history was assessed with the fifth question of the SARC-F questionnaire. Data normality was assessed with the Shapiro-Wilk test. The association of the sarcopenia parameters with a falls history was analyzed with the chi-square test and Cramér’s V to measure effect size.
Results No association was found among the parameters of sarcopenia or its diagnosis and a history of falls in this population (p > 0.05). Participants who reported falling in the previous year were older (60 ± 16.7 vs. 51 ± 14.7 years, p = 0.01) and had a history of cerebrovascular disease (14.3% vs. 2.4%, p = 0.02).
Conclusion Falls history was not associated with muscle strength or mass in ESRD patients in HD. Future longitudinal studies are needed to investigate other factors associated with this outcome.
Competing Interest StatementThe authors have declared no competing interest.
Funding StatementThis study was funded by the Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq) and the Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES).
Author DeclarationsI confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
Yes
The details of the IRB/oversight body that provided approval or exemption for the research described are given below:
Comite Permanente de Etica em Pesquisa com Seres Humanos of Universidade Estadual de Maringa gave ethical approval for this work.
I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals.
Yes
I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance).
Yes
I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable.
Yes
FootnotesFunding agencies: Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
This manuscript is based on the work presented at the X Congresso Brasileiro de Metabolismo, Nutrição e Exercício (CONBRAMENE); Londrina, Paraná, Brasil; May 15th, 2025.
Conflicts of Interest Statement: The authors declare no conflicts of interest related to this work.
Data AvailabilityAll data produced in the present study are available upon reasonable request to the authors.
Comments (0)