Siegel RL, Giaquinto AN, Jemal A (2024) Cancer statistics, 2024. CA Cancer J Clin 74(1):12–49. https://doi.org/10.3322/caac.21820

Article  PubMed  Google Scholar 

Hong R, Xu B (2022) Breast cancer: an up-to-date review and future perspectives. Cancer Commun (Lond) 42(10):913–936. https://doi.org/10.1002/cac2.12358

Article  PubMed  Google Scholar 

Dandawate PR, Subramaniam D, Jensen RA, Anant S (2016) Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy. Semin Cancer Biol 40–41:192–208. https://doi.org/10.1016/j.semcancer.2016.09.001

Article  CAS  PubMed  PubMed Central  Google Scholar 

Rueda OM, Sammut SJ, Seoane JA, Chin SF, Caswell-Jin JL, Callari M, Batra R, Pereira B, Bruna A, Ali HR et al (2019) Dynamics of breast-cancer relapse reveal late-recurring ER-positive genomic subgroups. Nature 567(7748):399–404. https://doi.org/10.1038/s41586-019-1007-8

Article  CAS  PubMed  PubMed Central  Google Scholar 

Nassar D, Blanpain C (2016) Cancer stem cells: basic concepts and therapeutic implications. Annu Rev Pathol 11:47–76. https://doi.org/10.1146/annurev-pathol-012615-044438

Article  CAS  PubMed  Google Scholar 

Henkin RI (2019) Clinical and therapeutic implications of Cancer stem cells. N Engl J Med 381(10):e19. https://doi.org/10.1056/NEJMc1908886

Article  PubMed  Google Scholar 

Tharmapalan P, Mahendralingam M, Berman HK, Khokha R (2019) Mammary stem cells and progenitors: targeting the roots of breast cancer for prevention. EMBO J 38(14):e100852. https://doi.org/10.15252/embj.2018100852

Article  CAS  PubMed  PubMed Central  Google Scholar 

He H, Xiao L, Wang J, Guo D, Lu Z (2023) Aerobic Glycolysis promotes tumor immune evasion and tumor cell stemness through the noncanonical function of hexokinase 2. Cancer Commun (Lond) 43(3):387–390. https://doi.org/10.1002/cac2.12404

Article  PubMed  Google Scholar 

Zhang S, Pei Y, Zhu F (2023) Multi-omic analysis of glycolytic signatures: exploring the predictive significance of heterogeneity and stemness in immunotherapy response and outcomes in hepatocellular carcinoma. Front Mol Biosci 10:1210111. https://doi.org/10.3389/fmolb.2023.1210111

Article  CAS  PubMed  PubMed Central  Google Scholar 

Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D et al (2017) Lactate Metabolism in Human Lung Tumors. Cell 171 (2):358–371.e359. https://doi.org/10.1016/j.cell.2017.09.019

Stouras I, Vasileiou M, Kanatas PF, Tziona E, Tsianava C, Theocharis S (2023) Metabolic profiles of cancer stem cells and normal stem cells and their therapeutic significance. Cells 12(23). https://doi.org/10.3390/cells12232686

Zhu T, Zheng J, Zhuo W, Pan P, Li M, Zhang W, Zhou H, Gao Y, Li X, Liu Z (2021) ETV4 promotes breast cancer cell stemness by activating Glycolysis and CXCR4-mediated Sonic Hedgehog signaling. Cell Death Discov 7(1):126. https://doi.org/10.1038/s41420-021-00508-x. (From NLM PubMed-not-MEDLINE)

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wang J, Zhu M, Zhu J, Li J, Zhu X, Wang K, Shen K, Yang K, Ni X, Liu X et al (2023) HES1 promotes aerobic Glycolysis and cancer progression of colorectal cancer via IGF2BP2-mediated GLUT1 m6A modification. Cell Death Discov 9(1):411. https://doi.org/10.1038/s41420-023-01707-4

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou J, Pei Y, Chen G, Cao C, Liu J, Ding C, Wang D, Sun L, Xu P, Niu G (2018) SPC24 regulates breast cancer progression by PI3K/AKT signaling. Gene 675:272–277. https://doi.org/10.1016/j.gene.2018.07.017From NLM Medline

Article  CAS  PubMed  Google Scholar 

Yiyan S, Yang S, Li D, Li W (2022) Vitamin D affects the Warburg effect and stemness maintenance of Non- Small-Cell lung Cancer cells by regulating the PI3K/AKT/mTOR signaling pathway. Curr Cancer Drug Targets 22(1):86–95. https://doi.org/10.2174/1568009621666210729100300. (From NLM Medline)

Article  CAS  PubMed  Google Scholar 

Ren J, Zhao S, Lai J (2024) Triptolide restrains the growth, invasion, stemness, and Glycolysis of non-small cell lung cancer cells by PFKFB2-mediated PI3K/AKT pathway. Chem Biol Drug Des 103(1):e14450. https://doi.org/10.1111/cbdd.14450From NLM Medline

Article  CAS  PubMed  Google Scholar 

Cheeseman IM, Desai A (2008) Molecular architecture of the kinetochore-microtubule interface. Nat Rev Mol Cell Biol 9(1):33–46. https://doi.org/10.1038/nrm2310

Article  CAS  PubMed  Google Scholar 

Lee H (2014) How chromosome mis-segregation leads to cancer: lessons from BubR1 mouse models. Mol Cells 37(10):713–718. https://doi.org/10.14348/molcells.2014.0233

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou J, Yu Y, Pei Y, Cao C, Ding C, Wang D, Sun L, Niu G (2017) A potential prognostic biomarker SPC24 promotes tumorigenesis and metastasis in lung cancer. Oncotarget 8(39):65469–65480. https://doi.org/10.18632/oncotarget.18971

Article  PubMed  PubMed Central  Google Scholar 

Wang Y, Yang H, Zhang G, Luo C, Zhang S, Luo R, Deng B (2021) hsa-miR-7-5p suppresses proliferation, migration and promotes apoptosis in hepatocellular carcinoma cell lines by inhibiting SPC24 expression. Biochem Biophys Res Commun 561:80–87. https://doi.org/10.1016/j.bbrc.2021.05.020

Article  CAS  PubMed  Google Scholar 

Yin H, Meng T, Zhou L, Chen H, Song D (2017) SPC24 is critical for anaplastic thyroid cancer progression. Oncotarget 8(13):21884–21891. https://doi.org/10.18632/oncotarget.15670

Article  PubMed  PubMed Central  Google Scholar 

Liu N, Jing Z, Wen-Qi D, Ting-Ting L, Cong W, Li-Na H, Feng-Ying Y, Hong-Wei Y, Di G (2023) Natural compound So-2 suppresses triple-negative breast cancer through inducing ferroptosis via downregulating transcription factor E2F7. Arch Biochem Biophys 744:109694. https://doi.org/10.1016/j.abb.2023.109694From NLM Medline

Article  CAS  PubMed  Google Scholar 

Jin Z, Xu W, Yu K, Luo C, Luo X, Lian T, Liu C (2024) The novel circFKBP8/miR-432-5p/E2F7 cascade functions as a regulatory network in breast cancer. Hereditas 161(1):27. https://doi.org/10.1186/s41065-024-00331-1From NLM Medline

Article  CAS  PubMed  PubMed Central  Google Scholar 

Waks AG, Winer EP (2019) Breast Cancer treatment: A review. JAMA 321(3):288–300. https://doi.org/10.1001/jama.2018.19323

Article  CAS  PubMed  Google Scholar 

Guo Q, Zhou Y, Xie T, Yuan Y, Li H, Shi W, Zheng L, Li X, Zhang W (2024) Tumor microenvironment of cancer stem cells: perspectives on cancer stem cell targeting. Genes Dis 11(3):101043. https://doi.org/10.1016/j.gendis.2023.05.024

Article  PubMed  Google Scholar 

DeLuca JG, Musacchio A (2012) Structural organization of the kinetochore-microtubule interface. Curr Opin Cell Biol 24(1):48–56. https://doi.org/10.1016/j.ceb.2011.11.003

Article  CAS  PubMed  Google Scholar 

Zhu P, Jin J, Liao Y, Li J, Yu XZ, Liao W, He S (2015) A novel prognostic biomarker SPC24 up-regulated in hepatocellular carcinoma. Oncotarget 6(38):41383–41397. https://doi.org/10.18632/oncotarget.5510

Article  PubMed  PubMed Central  Google Scholar 

Zhang J, Chen X, Wang J, Zhang P, Han X, Zhang Y, Wang Y, Yang X (2022) Bioinformatics analysis of prognostic value of SPC24 in CcRCC and Pan-Cancer. Int J Gen Med 15:817–836. https://doi.org/10.2147/IJGM.S348859

Article  CAS  PubMed  PubMed Central  Google Scholar 

Berger K, Pauwels E, Parkinson G, Landberg G, Le T, Demillo VG, Lumangtad LA, Jones DE, Islam MA, Olsen R et al (2021) Reduction of Progranulin-Induced breast Cancer stem cell propagation by Sortilin-Targeting Cyclotriazadisulfonamide (CADA) compounds. J Med Chem 64(17):12865–12876. https://doi.org/10.1021/acs.jmedchem.1c00943

Article