Treatment of Symptomatic Carotid Webs: Current Evidence and Future Directions

Mac Grory B, Nossek E, Reznik ME, et al. Ipsilateral internal carotid artery web and acute ischemic stroke: A cohort study, systematic review and meta-analysis. PLoS ONE. 2021;16: e0257697. https://doi.org/10.1371/journal.pone.0257697.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Haussen DC, Grossberg JA, Bouslama M, et al. Carotid web (intimal fibromuscular dysplasia) has high stroke recurrence risk and is amenable to stenting. Stroke. 2017;48:3134–7. https://doi.org/10.1161/STROKEAHA.117.019020.

Article  PubMed  Google Scholar 

Touzé E, Southerland AM, Boulanger M, et al. Fibromuscular dysplasia and its neurologic manifestations: A systematic review: a systematic review. JAMA Neurol. 2019;76:217–26. https://doi.org/10.1001/jamaneurol.2018.2848.

Article  PubMed  Google Scholar 

Wang LZ, Calvet D, Julia P, et al. Is carotid web an arterial wall dysplasia? A histological series. Cardiovasc Pathol. 2023;66:107544. https://doi.org/10.1016/j.carpath.2023.107544.

Article  PubMed  Google Scholar 

Sharashidze V, Nogueira RG, Al-Bayati AR, et al. Carotid web phenotype is uncommonly associated with classic fibromuscular dysplasia: A retrospective observational study. Stroke. 2022;53:e33–6. https://doi.org/10.1161/STROKEAHA.121.036188.

Article  PubMed  Google Scholar 

Olin JW, Gornik HL, Bacharach JM, et al. Fibromuscular dysplasia: state of the science and critical unanswered questions: a scientific statement from the american heart association: a scientific statement from the american heart association. Circulation. 2014;129:1048–78. https://doi.org/10.1161/01.cir.0000442577.96802.8c.

Article  PubMed  Google Scholar 

Chung C-T, Chen C-H, Lin Y-H, et al. Prevalence and clinical features of carotid artery web in patients undergoing endovascular thrombectomy for acute ischemic stroke. J Formos Med Assoc. Published Online First: 3 March 2024. https://doi.org/10.1016/j.jfma.2024.02.007.

Guglielmi V, Compagne KCJ, Sarrami AH, et al. Assessment of recurrent stroke risk in patients with a carotid web. JAMA Neurol. 2021;78:826–33. https://doi.org/10.1001/jamaneurol.2021.1101.

Article  PubMed  Google Scholar 

Kim SJ, Allen JW, Bouslama M, et al. Carotid webs in cryptogenic ischemic strokes: a matched case-control study. J Stroke Cerebrovasc Dis. 2019;28: 104402. https://doi.org/10.1016/j.jstrokecerebrovasdis.2019.104402.

Article  PubMed  Google Scholar 

Coutinho JM, Derkatch S, Potvin ARJ, et al. Carotid artery web and ischemic stroke: a case-control study. Neurology. 2017;88:65–9. https://doi.org/10.1212/WNL.0000000000003464.

Article  PubMed  PubMed Central  Google Scholar 

Khan F, Kala N, Chang K, et al. In-hospital recurrent stroke in ipsilateral carotid web patients undergoing thrombectomy. Ann Clin Transl Neurol. 2024.https://doi.org/10.1002/acn3.52161.

El-Masri S, Wilson MM, Kleinig T. Systematic review and meta-analysis of ipsilateral and contralateral carotid web prevalence in embolic supratentorial strokes of undetermined source. J Clin Neurosci. 2023;107:118–23. https://doi.org/10.1016/j.jocn.2022.12.010.

Article  PubMed  Google Scholar 

Goyal M, Singh N, Marko M, et al. Embolic stroke of undetermined source and symptomatic nonstenotic carotid disease. Stroke. 2020;51:1321–5. https://doi.org/10.1161/STROKEAHA.119.028853.

Article  CAS  PubMed  Google Scholar 

Sajedi P, Chelala L, Nunez-Gonalez J, et al. Carotid webs and ischemic stroke: experiences in a comprehensive stroke center. J Neuroradiol. 2019;46:136–40. https://doi.org/10.1016/j.neurad.2018.09.003.

Article  PubMed  Google Scholar 

Abdelhamid HM, Bhatt NR, Viana LS, et al. Multiplane reconstruction modifies the diagnostic performance of CT angiography in carotid webs. Clin Neurol Neurosurg. 2024;244: 108441. https://doi.org/10.1016/j.clineuro.2024.108441.

Article  PubMed  Google Scholar 

Zelada-Ríos L, Barrientos-Imán D, Simbrón-Ribbeck L, et al. Importance of multiplanar reformation angiographic images for the detection of carotid web: a case series: a case series. Brain Circ. 2023;9:44–7. https://doi.org/10.4103/bc.bc_75_22.

Article  PubMed  PubMed Central  Google Scholar 

Kuang H, Tan X, Bala F, et al. Two-stage convolutional neural network for segmentation and detection of carotid web on CT angiography. J Neurointerv Surg. 2024;jnis-2024–021782. https://doi.org/10.1136/jnis-2024-021782

Mac Grory B, Emmer BJ, Roosendaal SD, et al. Carotid web: an occult mechanism of embolic stroke. J Neurol Neurosurg Psychiatry. 2020;91:1283–9. https://doi.org/10.1136/jnnp-2020-323938.

Article  PubMed  Google Scholar 

Schievink WI. Spontaneous dissection of the carotid and vertebral arteries. N Engl J Med. 2001;344:898–906. https://doi.org/10.1056/NEJM200103223441206.

Article  CAS  PubMed  Google Scholar 

Ospel JM, Kappelhof M, Ganesh A, et al. Symptomatic non-stenotic carotid disease: current challenges and opportunities for diagnosis and treatment. J Neurointerv Surg. 2024;16:418–24. https://doi.org/10.1136/jnis-2022-020005.

Article  PubMed  Google Scholar 

Saba L, Cau R, Murgia A, et al. Carotid plaque-RADS: a novel stroke risk classification system. JACC Cardiovasc Imaging. 2024;17:62–75.

Article  PubMed  Google Scholar 

Singh R-J, Menon BK. A carotid web with atherosclerotic plaque. Ann Neurol. 2023;94:203–4.

Article  PubMed  Google Scholar 

Tamazyan R, Yannoutsos A. Symptomatic carotid web with underlying thrombus. Eur J Vasc Endovasc Surg. 2021;61:602. https://doi.org/10.1016/j.ejvs.2021.01.040.

Article  PubMed  Google Scholar 

Kodankandath TV. Delayed thrombus on carotid web: case report with escalation of treatment. Neurohospitalist. 2022;12:352–4. https://doi.org/10.1177/19418744211058940.

Article  PubMed  Google Scholar 

Wang Y, Li H-L, Xu X-H, et al. New asymptomatic thrombosis caused by carotid web during the acute period of cerebral infarction. BMC Neurol. 2023;23:264. https://doi.org/10.1186/s12883-023-03316-1.

Article  PubMed  PubMed Central  Google Scholar 

Bala F, Alhabli I, Singh N, et al. Relationship between carotid web morphology on CT angiography and stroke: a pooled multicenter analysis. Int J Stroke. 2024;17474930241264140. https://doi.org/10.1177/17474930241264141.

Pereira BJA, Batista UC, Tosello RT, et al. Web vessels: literature review and neurointerventional management. World Neurosurg. 2018;110:e907–16. https://doi.org/10.1016/j.wneu.2017.11.115.

Article  PubMed  Google Scholar 

Madaelil TP, Grossberg JA, Nogueira RG, et al. Multimodality imaging in carotid web. Front Neurol. 2019;10: 220. https://doi.org/10.3389/fneur.2019.00220.

Article  PubMed  PubMed Central  Google Scholar 

Damiani Monteiro M, Tarek MA, Martins PN, et al. Carotid web catheter angiography hemodynamic parameters. J Neurointerv Surg. 2024. https://doi.org/10.1136/jnis-2024-021948

Pasarikovski CR, Lynch J, Corrin M et al., Carotid stenting for symptomatic carotid artery web: Multicenter experience. Interv Neuroradiol. 2024;15910199231226292. https://doi.org/10.1177/15910199231226293.

Radu RA, Cagnazzo F, Derraz I, et al. Use of optical coherence tomography in selected patients with recurrent cryptogenic stroke: a case series and technical discussion. Interv Neuroradiol. 2023;15910199221150472. https://doi.org/10.1177/15910199221150472.

Oushy S, Flemming KD, Cloft H, et al. Use of intravascular optical coherence tomography to confirm the diagnosis of a carotid web in a patient with recurrent ipsilateral embolic strokes and evaluate the response to stenting. Interv Neuroradiol. 2023;29:217–21. https://doi.org/10.1177/15910199221080878.

Article  PubMed  Google Scholar 

Brinster CJ, O’Leary J, Hayson A, et al. Symptomatic carotid webs require aggressive intervention. J Vasc Surg. 2024;79:62–70. https://doi.org/10.1016/j.jvs.2023.09.002.

Article  PubMed  Google Scholar 

Zhou Q, Li R, Feng S, et al. The value of contrast-enhanced ultrasound in the evaluation of carotid web. Front Neurol. 2022;13: 860979. https://doi.org/10.3389/fneur.2022.860979.

Article  PubMed  PubMed Central  Google Scholar 

El Sayed R, Sharifi A, Park CC, et al. Optimization of 4D flow MRI spatial and temporal resolution for examining complex hemodynamics in the carotid artery bifurcation. Cardiovasc Eng Technol. 2023;14:476–88. https://doi.org/10.1007/s13239-023-00667-1.

Article  PubMed  PubMed Central  Google Scholar 

El Sayed R, Park CC, Shah Z, et al. Assessment of complex flow patterns in patients with carotid webs, patients with carotid atherosclerosis, and healthy subjects using 4D flow MRI. J Magn Reson Imaging. 2024;59:2001–10. https://doi.org/10.1002/jmri.29013.

Article  PubMed 

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