Evaluation of the consumption pattern and efficacy of Linezolid in COVID-19 hospitalized patients in a hospital in Tehran-Iran

Valencia DN. Brief review on COVID-19: the 2020 pandemic caused by SARS-CoV-2. Cureus. 2020;12(3):e7386.

PubMed  PubMed Central  Google Scholar 

Malik YS, Kumar N, Sircar S, et al. Coronavirus disease pandemic (COVID-19): challenges and a global perspective. Pathogens. 2020;9(7):519.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Contini C, Di Nuzzo M, Barp N, et al. The novel zoonotic COVID-19 pandemic: An expected global health concern. J Infect Dev Countries. 2020;14(03):254–64.

Article  CAS  Google Scholar 

Ye Z-W, Jin D-Y. Diagnosis, treatment, control and prevention of SARS-CoV-2 and coronavirus disease 2019: back to the future. Sheng wu gong cheng xue bao= Chin J Biotechnol. 2020;36(4):571–92.

Google Scholar 

Cascella M, Rajnik M, Aleem A, et al. Features, evaluation, and treatment of Coronavirus (COVID-19). 2023 Aug 18. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024.

Lu H. Drug treatment options for the 2019-new coronavirus (2019-nCoV). Biosci Trends. 2020;14(1):69–71.

Article  CAS  PubMed  Google Scholar 

Reardon S. Antibiotic treatment for COVID-19 complications could fuel resistant bacteria. Available from: https://www.science.org/content/article/antibiotic-treatment-covid-19-complications-could-fuel-resistant-bacteria. Accessed 16 Apr 2020.

Zhou F, Yu T, Du R, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020;395(10229):1054–62.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Adebisi YA, Jimoh ND, Ogunkola IO, et al. The use of antibiotics in COVID-19 management: a rapid review of national treatment guidelines in 10 African countries. Trop Med Health. 2021;49(1):51.

Article  PubMed  PubMed Central  Google Scholar 

Batts DH. Linezolid–a new option for treating gram-positive infections. Oncology (Williston Park). 2000;14(8 Suppl 6):23–9.

CAS  PubMed  Google Scholar 

Zurenko GE, Gibson JK, Shinabarger DL, et al. Oxazolidinones: a new class of antibacterials. Curr Opin Pharmacol. 2001;1(5):470–6.

Article  CAS  PubMed  Google Scholar 

Brickner SJ, Hutchinson DK, Barbachyn MR, et al. Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections. J Med Chem. 1996;39(3):673–9.

Article  CAS  PubMed  Google Scholar 

Moellering RC Jr. Linezolid: the first oxazolidinone antimicrobial. Ann Intern Med. 2003;139(10):864.

Article  Google Scholar 

Eid RA, Elgendy MO, Sayed AM, et al. Efficacy of Linezolid in the management of pneumonic COVID-19 patients. Bioinformatics-based clinical study. J Infect Dev Countries. 2024;18(3):326–31.

Article  Google Scholar 

Moghadam VD, Momenimovahed Z, Ghorbani M, et al. Linezolid a potential treatment for COVID-19 coinfections. Braz J Anesthesiol. 2021;71:198–198.

PubMed  PubMed Central  Google Scholar 

Zhang J, Ma X, Yu F, et al. Teicoplanin potently blocks the cell entry of 2019-nCoV. biorxiv. 2020.

Getahun H, Smith I, Trivedi K, et al. Tackling antimicrobial resistance in the COVID-19 pandemic. Bull World Health Organ. 2020;98(7):442.

Article  PubMed  PubMed Central  Google Scholar 

Kumar A, Taneja A, Pal Singh Y, et al. Relationship between COVID-19 and Linezolid-Resistant Enterococci: a retrospective single-center study. Cureus. 2024;16(3):e57227.

PubMed  PubMed Central  Google Scholar 

Bell BG, Schellevis F, Stobberingh E, et al. A systematic review and meta-analysis of the effects of antibiotic consumption on antibiotic resistance. BMC Infect Dis. 2014;14(1):1–25.

Article  Google Scholar 

Hopkins C. Inpatient antibiotic consumption in a regional secondary hospital in N ew Z ealand. Intern Med J. 2014;44(2):185–90.

Article  CAS  PubMed  Google Scholar 

Green T. Drug and therapeutics committees: a practical guide. In: Holloway K, ‎editor. World Health Organization. ‎2003‎. Available from: https://iris.who.int/handle/10665/68553.

Najafi S, Keshavarz-Bahaghighat H, Kohneloo AJ, et al. A Survey of Linezolid Prescription before and after protocol implementation in a teaching hospital. J Pharm Care. 2018;5(1–2):16–20.

Google Scholar 

World Health Organization (WHO). Available from: https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance#:~:text=AMR%20is%20a%20natural%20process,in%20humans%2C%20animals%20and%20plants. Accessed 21 Nov 2023

Pulcini C, Botelho-Nevers E, Dyar OJ, et al. The impact of infectious disease specialists on antibiotic prescribing in hospitals. Clin Microbiol Infect. 2014;20(10):963–72.

Article  CAS  PubMed  Google Scholar 

Cavalcanti AB, Goncalves AR, Almeida CS, et al. Teicoplanin versus vancomycin for proven or suspected infection. Cochrane Database Syst Rev. 2010;6. https://doi.org/10.1002/14651858.CD007022.pub2.

Wang J, Tang Y, Ma Y, et al. Efficacy and safety of antibiotic agents in children with COVID-19: a rapid review. Ann Transl Med. 2020;8(10):619.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khan M, Ara N. Promoting rational prescribing among medical practitioners. Bangladesh Med J. 2011;40(2):6–7.

Article  Google Scholar 

Manfredi R. Update on the appropriate use of linezolid in clinical practice. Ther Clin Risk Manag. 2006;2(4):455–64.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ament PW, Jamshed N, Horne JP. Linezolid: its role in the treatment of gram-positive, drug-resistant bacterial infections. Am Fam Physician. 2002;65(4):663–71.

PubMed  Google Scholar 

Vinh DC, Rubinstein E. Linezolid: a review of safety and tolerability. J Infect. 2009;59:S59–74.

Article  PubMed  Google Scholar 

Zhang D, Xu Y, Wang X, et al. Risk factors for thrombocytopenia in patients receiving linezolid therapy: a systematic review and meta-analysis. Eur J Clin Pharmacol. 2023;79(10):1303–14.

Article  CAS  PubMed  Google Scholar 

Zong X, Gu Y, Yu H, et al. Thrombocytopenia is associated with COVID-19 severity and outcome: an updated meta-analysis of 5637 patients with multiple outcomes. Lab Med. 2021;52(1):10–5.

Article  PubMed  Google Scholar 

Comments (0)

No login
gif