Phase angle as an independent predictor of sarcopenia and glycemic control in older adults with type 2 diabetes: a cross-sectional observational study

Bellary S, Kyrou I, Brown JE, Bailey CJ. Type 2 diabetes mellitus in older adults: clinical considerations and management. Nat Rev Endocrinol. 2021;17:534–8. https://doi.org/10.1038/s41574-021-00512-2.

Article  PubMed  Google Scholar 

Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48:16–31. https://doi.org/10.1093/ageing/afy169.

Article  PubMed  Google Scholar 

Papadopoulou SK, Sarcopenia. A contemporary health problem among older adult populations. Nutrients. 2020;12:1293. https://doi.org/10.3390/nu12051293.

Article  PubMed  PubMed Central  Google Scholar 

Xie WQ, He M, Yu DJ, Wu YX, Wang XH, Lv S, et al. Mouse models of sarcopenia: classification and evaluation. J Cachexia Sarcopenia Muscle. 2021;12:538–54. https://doi.org/10.1002/jcsm.12709.

Article  PubMed  PubMed Central  Google Scholar 

Hatef B, Bahrpeyma F, Mohajeri Tehrani MR. The comparison of muscle strength and short-term endurance in the different periods of type 2 diabetes. J Diabetes Metab Disord. 2014;13:22. https://doi.org/10.1186/2251-6581-13-22.

Article  PubMed  PubMed Central  Google Scholar 

Akamatsu Y, Kusakabe T, Arai H, Yamamoto Y, Nakao K, Ikeue K, et al. Phase angle from bioelectrical impedance analysis is a useful indicator of muscle quality. J Cachexia Sarcopenia Muscle. 2022;13:180–9. https://doi.org/10.1002/jcsm.12860.

Article  PubMed  Google Scholar 

Bellido D, García-García C, Talluri A, Lukaski HC, García-Almeida JM. Future lines of research on phase angle: strengths and limitations. Rev Endocr Metab Disord. 2023;24:563–83. https://doi.org/10.1007/s11154-023-09803-7.

Article  PubMed  PubMed Central  Google Scholar 

Choi HN, Kim KA, Kim YS, Yim JE. Independent association of phase angle with fasting blood glucose and hemoglobin A1c in Korean type 2 diabetes patients. Clin Nutr Res. 2020;9:205–12. https://doi.org/10.7762/cnr.2020.9.3.205.

Article  PubMed  PubMed Central  Google Scholar 

Alabadi B, Civera M, De la Rosa A, Martinez-Hervas S, Gomez-Cabrera MC, Real JT. Low muscle mass is associated with poorer glycemic control and higher oxidative stress in older patients with type 2 diabetes. Nutrients. 2023;15:3167. https://doi.org/10.3390/nu15143167.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Wu CN, Tien KJ. The impact of antidiabetic agents on sarcopenia in type 2 diabetes: A literature review. J Diabetes Res. 2020;9:9368583. https://doi.org/10.1155/2020/9368583.

Article  CAS  Google Scholar 

Yamada Y, Buehring B, Krueger D, Anderson RM, Schoeller DA, Binkley N. Electrical properties assessed by bioelectrical impedance spectroscopy as biomarkers of age-related loss of skeletal muscle quantity and quality. J Gerontol Biol Sci Med Sci. 2017;72:1180–6. https://doi.org/10.1093/gerona/glw225.

Article  Google Scholar 

Kuschel LB, Sonnenburg D, Engel T. Factors of muscle quality and determinants of muscle strength: A systematic literature review. Healthcare. 2022;10:1937. https://doi.org/10.3390/healthcare10101937.

Article  PubMed  PubMed Central  Google Scholar 

Yamada M, Kimura Y, Ishiyama D, Nishio N, Otobe Y, Tanaka T, et al. Phase angle is a useful indicator for muscle function in older adults. J Nutr Health Aging. 2019;23:251–5. https://doi.org/10.1007/s12603-018-1151-0.

Article  CAS  PubMed  Google Scholar 

Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, et al. Asian working group for sarcopenia: 2019 consensus update on sarcopenia diagnosis and treatment. J Am Med Dir Assoc. 2020;21:300–e72. https://doi.org/10.1016/j.jamda.2019.12.012.

Article  PubMed  Google Scholar 

Walston JD. Sarcopenia in older adults. Curr Opin Rheumatol. 2012;24:623–7. https://doi.org/10.1097/BOR.0b013e328358d59b.

Article  PubMed  PubMed Central  Google Scholar 

Veronese N, Smith L, Barbagallo M, Yang L, Zou L, Haro JM, et al. Sarcopenia and fall-related injury among older adults in five low- and middle-income countries. Exp Gerontol. 2021;147:111262. https://doi.org/10.1016/j.exger.2021.111262.

Article  PubMed  Google Scholar 

Gandham A, Gregori G, Johansson L, Johansson H, Harvey NC, Vandenput L, et al. Sarcopenia definitions and their association with fracture risk in older Swedish women. J Bone Min Res. 2024;39:453–61. https://doi.org/10.1093/jbmr/zjae026.

Article  Google Scholar 

Zhang X, Zhang W, Wang C, Tao W, Dou Q, Yang Y. Sarcopenia as a predictor of hospitalization among older people: A systematic review and meta-analysis. BMC Geriatr. 2018;18:188. https://doi.org/10.1186/s12877-018-0878-0.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Takahashi F, Hashimoto Y, Kaji A, Sakai R, Okamura T, Kitagawa N, et al. Sarcopenia is associated with a risk of mortality in people with type 2 diabetes mellitus. Front Endocrinol (Lausanne). 2021;12:783363. https://doi.org/10.3389/fendo.2021.783363.

Article  PubMed  Google Scholar 

Dias C, Nylandsted J. Plasma membrane integrity in health and disease: significance and therapeutic potential. Cell Discov. 2021;7:4. https://doi.org/10.1038/s41421-020-00233-2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Marzetti E, Lees HA, Wohlgemuth SE, Leeuwenburgh C. Sarcopenia of aging: underlying cellular mechanisms and protection by calorie restriction. BioFactors. 2009;35:28–35. https://doi.org/10.1002/biof.5.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Zhou S, Yu Z, Shi X, Zhao H, Dai M, Chen W. The relationship between phase angle, nutrition status, and complications in patients with pancreatic head cancer. Int J Environ Res Public Health. 2022;19:6426. https://doi.org/10.3390/ijerph19116426.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ruiz-Margáin A, Macías-Rodríguez RU, Duarte-Rojo A, Ríos-Torres SL, Espinosa-Cuevas Á, Torre A. Malnutrition assessed through phase angle and its relation to prognosis in patients with compensated liver cirrhosis: A prospective cohort study. Dig Liver Dis. 2015;47:309–14. https://doi.org/10.1016/j.dld.2014.12.015.

Article  PubMed  Google Scholar 

Purnamasari D, Tetrasiwi EN, Kartiko GJ, Astrella C, Husam K, Laksmi PW. Sarcopenia and chronic complications of type 2 diabetes mellitus. Rev Diabet Stud. 2022;18:157–65. https://doi.org/10.1900/RDS.2022.18.157.

Article  PubMed  PubMed Central  Google Scholar 

Singh VP, Bali A, Singh N, Jaggi AS. Advanced glycation end products and diabetic complications. Korean J Physiol Pharmacol. 2014;18:1–14. https://doi.org/10.4196/kjpp.2014.18.1.1.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Petersen MC, Shulman GI. Mechanisms of insulin action and insulin resistance. Physiol Rev. 2018;98:2133–223. https://doi.org/10.1152/physrev.00063.2017.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Martins AD, Fernandes O, Oliveira R, Bilro V, Lopes G, Rego AM, et al. Effects of exercise programs on phase angle in older adults: A systematic review and meta-analysis. Arch Gerontol Geriatr. 2022;103:104787. https://doi.org/10.1016/j.archger.2022.104787.

Article  PubMed  Google Scholar 

Cereda E, Turri A, Klersy C, Cappello S, Ferrari A, Filippi AR, et al. Whey protein isolate supplementation improves body composition, muscle strength, and treatment tolerance in malnourished advanced cancer patients undergoing chemotherapy. Cancer Med. 2019;8:6923–32. https://doi.org/10.1002/cam4.2517.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Feng L, Li B, Yong SS, Wu X, Tian Z. Exercise and nutrition benefit skeletal muscle: from influence factor and intervention strategy to molecular mechanism. Sports Med Health Sci. 2024;6:302–14.

Comments (0)

No login
gif