6-Gingerol ameliorates alveolar hypercoagulation and fibrinolytic inhibition in LPS-provoked ARDS via RUNX1/NF-κB signaling pathway
Keywords
6-Gingerol
Alveolar hypercoagulation
Fibrinolytic inhibition
Acute respiratory distress syndrome
Runt-related transcription factor 1
NF-κB signaling pathway
AbbreviationsARDS
Acute respiratory distress syndrome
RUNX1
runt-related transcription factor 1
AECII
alveolar epithelial cells type II
PAI-1
plasminogen activator inhibitor 1
BALF
bronchial alveolar lavage fluid
(NF-κB
nuclear factor kappa-B
ECMO
extracorporeal membrane oxygenation
BALF
bronchoalveolar lavage fluid
qRT-PCR
quantitative real-time PCR
ELISA
enzyme linked immunosorbent
Phosphorylation
p65(p-p65)
p- IKKβ
phosphorylation – IKKβ
Data availability
Data will be made available on request.
© 2023 The Author(s). Published by Elsevier B.V.
Comments (0)