Sedentary behaviour is distinct from physical inactivity and is defined as “any waking behaviour characterized by an energy expenditure ≤1.5 metabolic equivalent units (METs) while in a sitting, lying, or reclining posture” (Tremblay et al., 2017). It was determined that as the duration of the disease and the functional limitations caused by the disease increased in persons with multiple sclerosis (pwMS), the level of physical activity decreased, a sedentary lifestyle was established, and they were less active than healthy individuals in the same age group (Beckerman et al., 2010). Furthermore, it has been reported that low levels of physical activity and exercise and high levels of sedentary behaviour are common in pwMS, despite a consensus that physical activity is mandatory in pwMS (Hubbard et al., 2015).

Sedentary behaviour assessment is a relatively new and important field for preventive physiotherapy as well as physical activity assessment. As stated by the world health organization (WHO), sedentary behaviour assessments are gaining importance in order to prevent possible health consequences and to determine the measures and methods to be taken. Detailed analysis of sedentary behaviour assessments and identifying related factors will be guiding for these methods (Bull et al., 2020).

Despite the fact that pwMS have a sedentary lifestyle, relatively few studies have examined sedentary behaviour and related factors in this population. There are many possible factors that influence physical activity participation in pwMS. So far, studies have consistently reported that greater levels of sedentary behaviour are associated with more severe disability (Ezeugwu et al., 2015; Veldhuijzen Van Zanten et al., 2016). Additionally, pwMS describe a significant decrease in their physical activity levels compared to pre-disease levels, and in addition to this, they state that they develop a fear of physical activity (Ertekin et al., 2014; Kinnett-Hopkins et al., 2017). There is a need for studies examining the effects of demographic, clinical, physical, and psychosocial outcome measures that may affect sedentary behaviour in pwMS. Therefore, the aim of this study was to explore the relationship between self-reported sedentary behaviour and physical activity level, fear of falling, and fatigue. Evaluation of this relationship might be important as it will guide the rehabilitation team in overcoming the barriers to physical activity participation in pwMS.