Al Habash A, Aljasim LA, Owaidhah O, Edward DP. A review of the efficacy of mitomycin C in glaucoma filtration surgery. Clin Ophthalmol. 2015;9:1945–51.

CAS  PubMed  PubMed Central  Google Scholar 

Urbaneja D, Morilla-Grasa A, Jimenez E, Montemayor J, Marcobal N, Aragay C, et al. In vitro mitomycin C absorption and delivery with different sponge materials used in filtering surgery. Clin Ophthalmol. 2016;10:665–9.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Khamar M, Bhojwani D, Patel P, Vasavada A. Leftover mitomycin-c sponge causing blebitis. Indian J Ophthalmol. 2019;67:1753–5.

Article  PubMed  PubMed Central  Google Scholar 

Bell K, de Padua Soares Bezerra B, Mofokeng M, Montesano G, Nongpiur ME, Marti MV, et al. Learning from the past: Mitomycin C use in trabeculectomy and its application in bleb-forming minimally invasive glaucoma surgery. Surv Ophthalmol. 2021;66:109–23.

Article  PubMed  Google Scholar 

Kandarakis SA, Papakonstantinou E, Petrou P, Diagourtas A, Ifantides C, Georgalas I, et al. One-year randomized comparison of safety and efficacy of trabeculectomy with mitomycin C sub-tenon injection versus mitomycin C-infused sponges. Ophthalmol Glaucoma. 2022;5:77–84.

Article  PubMed  Google Scholar 

Lee E, Doyle E, Jenkins C. Trabeculectomy surgery augmented with intra-Tenon injection of mitomycin C. Acta Ophthalmol. 2008;86:866–70.

Article  PubMed  Google Scholar 

Do JL, Xu BY, Wong B, Camp A, Ngai P, Long C, et al. A randomized controlled trial comparing subconjunctival injection to direct scleral application of mitomycin C in trabeculectomy. Am J Ophthalmol. 2020;220:45–52.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Hung PT. Mitomycin-C in glaucoma filtering surgery. Asia Pac Ophthalmol. 2000;2:21–4.

Google Scholar 

Maheshwari D, Kanduri S, Rengappa R, Kadar MA. Intraoperative injection versus sponge-applied mitomycin C during trabeculectomy: one-year study. Indian J Ophthalmol. 2020;68:615–9.

Article  PubMed  PubMed Central  Google Scholar 

Chiew W, Guo X, Ang BCH, Lim APH, Yip LWL. Comparison of surgical outcomes of sponge application versus subconjunctival injection of mitomycin-C during combined phacoemulsification and trabeculectomy surgery in asian eyes. J Curr Ophthalmol. 2021;33:253–9.

Article  PubMed  PubMed Central  Google Scholar 

Khouri AS, Huang GY, Huang L. Intraoperative Injection vs Sponge-applied Mitomycin C during Trabeculectomy: one-year study. J Curr Glaucoma Pract. 2017;11:101–6.

Article  Google Scholar 

Esfandiari H, Pakravan M, Yazdani S, Doozandeh A, Yaseri M, Conner IP. Treatment outcomes of mitomycin C-augmented trabeculectomy, sub-tenon injection versus soaked sponges, after 3 years of follow-up: a randomized clinical trial. Ophthalmol Glaucoma. 2018;1:66–74.

Article  PubMed  Google Scholar 

Ahmadzadeh A, Kessel L, Subhi Y, Bach-Holm D. Comparative efficacy of phacotrabeculectomy versus trabeculectomy with or without later phacoemulsification: a systematic review with meta-analyses. J Ophthalmol. 2021;2021:6682534.

Article  PubMed  PubMed Central  Google Scholar 

Burns PB, Rohrich RJ, Chung KC. The levels of evidence and their role in evidence-based medicine. Plast Reconstr Surg. 2011;128:305–10.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Ogata-Iwao M, Inatani M, Takihara Y, Inoue T, Iwao K, Tanihara H. A prospective comparison between trabeculectomy with mitomycin C and phacotrabeculectomy with mitomycin C. Acta Ophthalmol. 2013;91:e500–1.

Article  PubMed  Google Scholar 

Kleinmann G, Katz H, Pollack A, Schechtman E, Rachmiel R, Zalish M. Comparison of trabeculectomy with mitomycin C with or without phacoemulsification and lens implantation. Ophthalmic Surg Lasers. 2002;33:102–8.

Article  PubMed  Google Scholar 

Lochhead J, Casson RJ, Salmon JF. Long term effect on intraocular pressure of phacotrabeculectomy compared to trabeculectomy. Br J Ophthalmol. 2003;87:850–2.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Sacchi M, Monsellato G, Villani E, Lizzio RAU, Cremonesi E, Luccarelli S, et al. Intraocular pressure control after combined phacotrabeculectomy versus trabeculectomy alone. Eur J Ophthalmol. 2022;32:327–35.

Article  PubMed  Google Scholar 

Mostafaei A. Augmenting trabeculectomy in glaucoma with subconjunctival mitomycin C versus subconjunctival 5-fluorouracil: a randomized clinical trial. Clin Ophthalmol. 2011;5:491–4.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Singh J, O’Brien C, Chawla HB. Success rate and complications of intraoperative 0.2 mg/ml mitomycin C in trabeculectomy surgery. Eye. 1995;9:460–6.

Article  PubMed  Google Scholar 

Lee JWY, Lai JSM, Yick DWF, Tse RKK. Retrospective case series on the long-term visual and intraocular pressure outcomes of phacomorphic glaucoma. Eye. 2010;24:1675–80.

Article  CAS  PubMed  Google Scholar 

Kanda Y. Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics. Bone Marrow Transplant. 2013;48:452–8.

Article  CAS  PubMed  Google Scholar 

Cochran WG. Some methods for strengthening the common χ2 tests. Biometrics. 1954;10:417–51.

Article  Google Scholar 

Wong JKW, Leung TK, Lai JS, Chan JC. Evaluation of adverse effects of topical glaucoma medications on trabeculectomy outcomes using the glaucoma medications intensity index. Ophthalmol Ther. 2022;11:387–401.

Article  PubMed  Google Scholar 

Husain R, Liang S, Foster PJ, Gazzard G, Bunce C, Chew PTK, et al. Cataract surgery after trabeculectomy: the effect on trabeculectomy function. Arch Ophthalmol. 2012;130:165–70.

Article  PubMed  Google Scholar 

Siriwardena D, Kotecha A, Minassian D, Dart J, Khaw P. Anterior chamber flare after trabeculectomy and after phacoemulsification. Br J Ophthalmol. 2000;84:1056–7.

Article  CAS  PubMed  PubMed Central  Google Scholar 

Cabourne E, Clarke JCK, Schlottmann PG, Evans JR. Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. Cochrane Database Syst Rev. 2015;2015:CD006259.

PubMed  PubMed Central  Google Scholar 

Farooq S, Farooq H, Faisal M. Outcome of intraoperative Mitomycin C injection in trabeculectomy and phacotrabeculectomy in patients with glaucoma. Pak J Ophthalmol. 2021;37:213–7.

Article  Google Scholar 

Guimarães ME, de Pádua Soares Bezerra B, de Miranda Cordeiro F, Carvalho CH, Danif DN, Prata TS, et al. Glaucoma surgery with soaked sponges with Mitomycin C vs sub-tenon injection: short-term outcomes. J Curr Glaucoma Pr. 2019;13:50–4.

Article  Google Scholar 

Murthy SK, Damji KF, Pan Y, Hodge WG. Trabeculectomy and phacotrabeculectomy, with mitomycin-C, show similar two-year target IOP outcomes. Can J Ophthalmol. 2006;41:51–9.

Article  PubMed  Google Scholar 

Bindlish R, Condon GP, Schlosser JD, D’Antonio J, Lauer KB, Lehrer R. Efficacy and safety of mitomycin-C in primary trabeculectomy: five-year follow-up. Ophthalmology. 2002;109:1336–41.

Article  PubMed  Google Scholar 

Janani MK, Jaichandran V, Madhavan HNR, Vijaya L, George RJ, Ambastha PS, et al. Effect of lignocaine concentration on human fibroblasts growth in eyes undergoing trabeculectomy: an in vitro study. Biomed Hub. 2018;3:1–10.

Article  PubMed  PubMed Central  Google Scholar 

Klifto MR, Fleischman D. pH of Mitomycin-C formulations for filtration surgery. J Glaucoma. 2019;28:647–8.

Article  PubMed  Google Scholar 

Park A, Hardin JS, Bora NS, Morshedi RG. Effects of lidocaine on mitomycin C cytotoxicity. Ophthalmol Glaucoma. 2021;4:330–5.

Article  PubMed  Google Scholar 

Mietz H, Diestelhorst M, Rump AF, Theisohn M, Klaus W, Krieglstein GK. Ocular concentrations of mitomycin C using different delivery devices. Ophthalmologica. 1998;212:37–42.

Article  CAS  PubMed  Google Scholar 

Sacu S, Rainer G, Findl O, Georgopoulos M, Vass C. Correlation between the early morphological appearance of filtering blebs and outcome of trabeculectomy with mitomycin C. J Glaucoma. 2003;12:430–5.

Article  PubMed  Google Scholar 

Lim MC, Hom B, Watnik MR, Brandt JD, Altman AR, Paul T, et al. A comparison of trabeculectomy surgery outcomes with Mitomycin-C applied by intra-tenon injection versus sponge. Am J Ophthalmol. 2020;216:243–56.

Article  CAS  PubMed  Google Scholar 

Mokbel TH, Ghanem AA, Moawad AI, Nafie EM, Nematallah EH. Comparative study of phacoemulsification-subscleral trabeculectomy versus phacoemulsification-deep sclerectomy. Saudi J Ophthalmol. 2009;23:189–96.

Article  PubMed  PubMed Central  Google Scholar 

Reps JM, Rijnbeek P, Cuthbert A, Ryan PB, Pratt N, Schuemie M. An empirical analysis of dealing with patients who are lost to follow-up when developing prognostic models using a cohort design. BMC Med Inf Decis Mak. 2021;21:43.

Article  Google Scholar