Pediatric Radiology was founded in 1973, with the goal of sharing new developments and new knowledge in the field of pediatric imaging with an international community of readers. Fifty years later, we can confidently say that we are meeting this goal. With close to 10,000 manuscripts indexed in PubMed®, Pediatric Radiology is the flagship international journal of pediatric imaging.

What started as 4 issues/year in 1973 grew to 12 issues/year by 1996 and subsequently, under the leadership of Peter J. Strouse and Øystein E. Olsen, to 13 issues/year in 2015. We are grateful to all previous editors for The Americas and for Outside the Americas for their vision and leadership. We are also indebted to each of our Assistant Editors who have contributed countless hours and their expertise to the journal. Most importantly, the contributions of our authors, peer reviewers, and editorial board have helped the journal deliver its goals of sharing pediatric radiology knowledge across the globe.

To celebrate 50 years of Pediatric Radiology, and to acknowledge the input of everyone who has contributed to the journal over this time, we have curated a Topical Collection of some of the most downloaded and/or most cited articles published in our journal over the last 50 years [1]. The articles are a small sample of scientific advances and educational reviews published in the journal and are those that have received the most attention. The topics cover the gamut from normative data to artificial intelligence. We welcome commentaries on how these articles have impacted your pediatric imaging practice and ongoing research.

This Topical Collection is shared with you, our colleagues and readers, to commemorate the 50th Anniversary of Pediatric Radiology, the official journal of the European Society of Paediatric Radiology, the Society for Pediatric Radiology, the Asian and Oceanic Society for Pediatric Radiology, and the Sociedad Latinoamericana de Radiología Pediátrica.

We hope you enjoy reading these articles (again) and congratulations!