Alpha-secretase dependent nuclear localization of the amyloid-β precursor protein-binding protein Fe65 promotes DNA repair

AbbreviationsADAM

A disintegrin and metalloprotease

AICD

APP intracellular domain

APP

amyloid-β precursor protein

DAPT

N-[N-(3,5-Difluorophenacetyl)- L-alanyl]-S-phenylglycine t-butyl ester

PMA

Phorbol 12-myristate 13-acetate

RA

all-trans retinoic acid

Keywords

Alzheimer's disease

Amyloid-β precursor protein

Alpha-secretase

Fe65

DNA repair

Data availability

The data sets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.

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